Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura D. V. May"'
Autor:
Greg Stratmann, Obhi D. Hazarika, Jeffrey W. Sall, Damon Yu, Ashkan Alkhamisi, Jason Leong, Laura D. V. May, Gabe R. Quitoriano, Nan Lin, Bradley H. Lee, Heather Brosnan, John Thomas Chan
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, vol 37, iss 1
BackgroundWith growing evidence that anesthesia exposure in infancy affects cognitive development, it is important to understand how distinct anesthetic agents and combinations can alter long-term memory. Investigations of neuronal death suggest that
Autor:
Alan Wilk, Rehan S. Alvi, Mortay V. Mendoza, Greg Stratmann, Allison M. Rowe, Jeremy N. Guggenheim, Marianna Yusupova, Gopal R. Lalchandani, Jeffrey W. Sall, Colleen M. Carlston, Elaine W. Lee, Maximilian S. Schaefer, Heidi E. Gonzalez, Elliott Woodward, Jennifer Shih, Heejae Kang, Philip E. Bickler, Vinuta Rau, Laura D. V. May
Publikováno v:
Anesthesiology. 116:586-602
Background Anesthesia given to immature rodents causes cognitive decline, raising the possibility that the same might be true for millions of children undergoing surgical procedures under general anesthesia each year. We tested the hypothesis that an
Autor:
Cheryl Chiu, Isobel A. Russell, Rehan S. Alvi, Ran Dai, Jeffrey W. Sall, Joseph S. Bell, Ban Ku, Margit W. Hrubos, Mitra Dowlatshahi, Greg Stratmann, Michael T. Lee, Laura D. V. May, Philip E. Bickler
Publikováno v:
Anesthesiology. 112:305-315
Background Roughly, 10% of elderly patients develop postoperative cognitive dysfunction. General anesthesia impairs spatial memory in aged rats, but the mechanism is not known. Hippocampal neurogenesis affects spatial learning and memory in rats, and
Publikováno v:
Anesthesia and analgesia. 110(2)
Anesthetic drugs cause brain cell death and long-term neurocognitive dysfunction in neonatal rats. Recently, human data also suggest that anesthesia early in life may cause cognitive impairment. The connection between cell death and neurocognitive de
Autor:
Greg Stratmann, Joseph S. Bell, Laura D. V. May, Frank J. van der Heusen, Michael J. Laster, Martin Krause, Heidi E. Gonzalez, Helge Eilers, Edmond I. Eger, Jeffrey W. Sall
Publikováno v:
Anesthesia and analgesia. 109(3)
Background While studying neurotoxicity in rats, we observed that the anesthetic minimum alveolar anesthetic concentration (MAC) of isoflurane decreases with increasing duration of anesthesia in 7-day-old but not in 60-day-old rats. After 15 min of a
Autor:
Kavel Visrodia, Vinuta Rau, Jeffrey W. Sall, Laura D. V. May, Michael T. Lee, Greg Stratmann, Ban Ku, Joseph S. Bell, Ran Dai, Rehan S. Alvi, Kathy R. Magnusson
Publikováno v:
Anesthesiology. 110(4)
Background: Anesthetic agents cause cell death in the developing rodent brain and long-term, mostly hippocampal-dependent, neurocognitive dysfunction. However, a causal link between thesefindings has not been shown. Postnatal hippocampal neurogenesis
Autor:
Michael T. Lee, Emanuel J. Zusmer, Rehan S. Alvi, Jeffrey W. Sall, Vinuta Rau, Ban Ku, Joan F. Hilton, Laura D. V. May, Kavel Visrodia, Atoosa Firouzian, Ran Dai, Brandi K. Ormerod, Joseph S. Bell, Jeremy N. Guggenheim, Greg Stratmann
Publikováno v:
Anesthesiology. 110(4)
Background: Millions of neonates undergo anesthesia each year. Certain anesthetic agents cause brain cell death and longterm neurocognitive dysfunction in postnatal day (P)7 rats. Despite its intuitive appeal, a causal link between cell death and neu