Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Laura D. Nelon"'
Autor:
Jinu Abraham, Laura D. Nelon, Courtney B. Kubicek, Aoife Kilcoyne, Sheila T. Hampton, Lee Ann Zarzabal, Francis J. Giles, Joel E. Michalek, Brian P. Rubin, Charles Keller
Publikováno v:
Sarcoma, Vol 2011 (2011)
Rhabdomyosarcoma is an aggressive childhood malignancy, accounting for more than 50% of all soft-tissue sarcomas in children. Even with extensive therapy, the survival rate among alveolar rhabdomyosarcoma patients with advanced disease is only 20%. T
Externí odkaz:
https://doaj.org/article/16e41bbcf37546db8d500089e75d780c
Autor:
Charles Keller, Suman Malempati, Brian P. Rubin, Brent M. Nowak, Robin D. LeGallo, Argiris Efstratiadis, Francis G. Giles, Laura D. Nelon, Amanda T. McCleish, Aoife Kilcoyne, Eri Taniguchi, Beverly S. Schaffer, Koichi Nishijo, Suresh I. Prajapati, Jinu Abraham
Supplementary Figures 1-4 from Evasion Mechanisms to Igf1r Inhibition in Rhabdomyosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1735e5aa40e2934ad2d28620c1abdfa
https://doi.org/10.1158/1535-7163.22502010.v1
https://doi.org/10.1158/1535-7163.22502010.v1
Autor:
Charles Keller, Anthony J. Infante, Charles B. Clifford, Joel E. Michalek, Brian P. Rubin, Martha A. Hanes, Leslea M. Sarro, Tohru Hosoyama, Inkyung Jung, Michelle M. Brady, Laura D. Nelon, Suresh I. Prajapati, Amanda T. McCleish, Courtney B. Kubicek, Joy M. Wortham, Marcia H. Grayson, Beverly S. Schaffer
Supplementary Figure 3 from Immune Competency of a Hairless Mouse Strain for Improved Preclinical Studies in Genetically Engineered Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c48e5e545a399473b6742074a30ebc1
https://doi.org/10.1158/1535-7163.22485380
https://doi.org/10.1158/1535-7163.22485380
Autor:
Charles Keller, Anthony J. Infante, Charles B. Clifford, Joel E. Michalek, Brian P. Rubin, Martha A. Hanes, Leslea M. Sarro, Tohru Hosoyama, Inkyung Jung, Michelle M. Brady, Laura D. Nelon, Suresh I. Prajapati, Amanda T. McCleish, Courtney B. Kubicek, Joy M. Wortham, Marcia H. Grayson, Beverly S. Schaffer
Supplementary Figure 1 from Immune Competency of a Hairless Mouse Strain for Improved Preclinical Studies in Genetically Engineered Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16d9dd69e68a6c9ea21cc19cc451f34
https://doi.org/10.1158/1535-7163.22485389
https://doi.org/10.1158/1535-7163.22485389
Autor:
Charles Keller, Anthony J. Infante, Charles B. Clifford, Joel E. Michalek, Brian P. Rubin, Martha A. Hanes, Leslea M. Sarro, Tohru Hosoyama, Inkyung Jung, Michelle M. Brady, Laura D. Nelon, Suresh I. Prajapati, Amanda T. McCleish, Courtney B. Kubicek, Joy M. Wortham, Marcia H. Grayson, Beverly S. Schaffer
Supplementary Figure 2 from Immune Competency of a Hairless Mouse Strain for Improved Preclinical Studies in Genetically Engineered Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5204d91919d67be7c4ffd342d855bbab
https://doi.org/10.1158/1535-7163.22485386.v1
https://doi.org/10.1158/1535-7163.22485386.v1
Autor:
Charles Keller, Brian P. Rubin, Denis C. Guttridge, Laura D. Nelon, Lee Ann Zarzabal, Joel E. Michalek, Koichi Nishijo, Suresh I. Prajapati, Jinu Abraham, Mohammed Imran Aslam, Tohru Hosoyama
Supplementary Figures S1-S3; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca8e4288b763a3cc4fd1e5aab1237a8
https://doi.org/10.1158/1078-0432.22442097.v1
https://doi.org/10.1158/1078-0432.22442097.v1
Autor:
Charles Keller, Brian P. Rubin, Denis C. Guttridge, Laura D. Nelon, Lee Ann Zarzabal, Joel E. Michalek, Koichi Nishijo, Suresh I. Prajapati, Jinu Abraham, Mohammed Imran Aslam, Tohru Hosoyama
Purpose: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. The alveolar subtype of rhabdomyosarcoma (ARMS) is a paradigm for refractory and incurable solid tumors because more than half of the children at diagnosis have eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c9ddba24c114b5403d3b075b389c3f
https://doi.org/10.1158/1078-0432.c.6518919.v1
https://doi.org/10.1158/1078-0432.c.6518919.v1
Autor:
Charles Keller, Anthony J. Infante, Charles B. Clifford, Joel E. Michalek, Brian P. Rubin, Martha A. Hanes, Leslea M. Sarro, Tohru Hosoyama, Inkyung Jung, Michelle M. Brady, Laura D. Nelon, Suresh I. Prajapati, Amanda T. McCleish, Courtney B. Kubicek, Joy M. Wortham, Marcia H. Grayson, Beverly S. Schaffer
Genetically engineered mouse models (GEMM) of cancer are of increasing value to preclinical therapeutics. Optical imaging is a cost-effective method of assessing deep-seated tumor growth in GEMMs whose tumors can be encoded to express luminescent or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73eaf09a9764b6c0c7513d595c6f6614
https://doi.org/10.1158/1535-7163.c.6531914
https://doi.org/10.1158/1535-7163.c.6531914
Autor:
Charles Keller, Jerry Y. Chang, Matthew E. Randolph, Joshua Cates, Bernard Wood, Ross T. Whitaker, Suresh I. Prajapati, Laura D. Nelon, Lisa Nevell
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
We compared the cranial base of newborn Pax7-deficient and wildtype mice using a computational shape modeling technology called particle-based modeling (PBM). We found systematic differences in the morphology of the basiooccipital bone, including a b
Autor:
Joel E. Michalek, Charles Keller, Yongjian Ouyang, Brian J. Druker, Ranadip Pal, Laura D. Nelon, Marc M. Loriaux, Francis J. Giles, Aoife Kilcoyne, Jason M. Glover, Jinu Abraham, Ying Xuan Chua, Jeffrey W. Tyner, Jennifer S. Carew, Brian P. Rubin
Publikováno v:
Biochemical and Biophysical Research Communications. 426:363-368
Alveolar rhabdomyosarcoma (aRMS) is a very aggressive sarcoma of children and young adults. Our previous studies have shown that small molecule inhibition of Pdgfra is initially very effective in an aRMS mouse model. However, slowly evolving, acquire