Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Laura D. Hover"'
Autor:
Chen He, Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin, Nathaniel Twarog, Laura D. Hover, Chang-Hyuk Kwon, Lawryn H. Kasper, Junyuan Zhang, Xiaoyu Li, James Dalton, Barbara Jonchere, Kimberly S. Mercer, Duane G. Currier, William Caufield, Yingzhe Wang, Jia Xie, Alberto Broniscer, Cynthia Wetmore, Santhosh A. Upadhyaya, Ibrahim Qaddoumi, Paul Klimo, Frederick Boop, Amar Gajjar, Jinghui Zhang, Brent A. Orr, Giles W. Robinson, Michelle Monje, Burgess B. Freeman III, Martine F. Roussel, Paul A. Northcott, Taosheng Chen, Zoran Rankovic, Gang Wu, Jason Chiang, Christopher L. Tinkle, Anang A. Shelat, Suzanne J. Baker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Patient-derived xenografts provide a resource for basic and translational cancer research. Here, the authors generate multiple pediatric high-grade glioma xenografts, use omics technologies to show that they are representative of primary tumours and
Externí odkaz:
https://doaj.org/article/879be8929790465bbe548678fef6db02
Autor:
Hong Wang, Alexander K. Diaz, Timothy I. Shaw, Yuxin Li, Mingming Niu, Ji-Hoon Cho, Barbara S. Paugh, Yang Zhang, Jeffrey Sifford, Bing Bai, Zhiping Wu, Haiyan Tan, Suiping Zhou, Laura D. Hover, Heather S. Tillman, Abbas Shirinifard, Suresh Thiagarajan, Andras Sablauer, Vishwajeeth Pagala, Anthony A. High, Xusheng Wang, Chunliang Li, Suzanne J. Baker, Junmin Peng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Multi-omic profiling is a powerful approach to dissecting molecular mechanisms in disease. Here the authors generate whole proteome, phosphoproteome and transcriptome profiles from two mouse models of high-grade glioma driven by different oncogenes,
Externí odkaz:
https://doaj.org/article/61f32b7ce86246f7a09c004f13127043
Autor:
Scott D. Cramer, Andrew Thorburn, James C. Fleet, Jason D. Hipp, Guangchao Sui, Linara S. Axanova, Laura D. Hover, Wendy W. Barclay, Sophia L. Maund
Supplementary Tables 5-7 from Interleukin-1α Mediates the Antiproliferative Effects of 1,25-Dihydroxyvitamin D3 in Prostate Progenitor/Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131f5e010e8f630d10c7fa0ba8ab8acd
https://doi.org/10.1158/0008-5472.22386450
https://doi.org/10.1158/0008-5472.22386450
Autor:
Scott D. Cramer, Andrew Thorburn, James C. Fleet, Jason D. Hipp, Guangchao Sui, Linara S. Axanova, Laura D. Hover, Wendy W. Barclay, Sophia L. Maund
Supplementary Table Legends 1-7, Figure Legends 1-9 from Interleukin-1α Mediates the Antiproliferative Effects of 1,25-Dihydroxyvitamin D3 in Prostate Progenitor/Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d021da9c8a1a04edfabf8eba0ba076
https://doi.org/10.1158/0008-5472.22386456
https://doi.org/10.1158/0008-5472.22386456
Autor:
Scott D. Cramer, Andrew Thorburn, James C. Fleet, Jason D. Hipp, Guangchao Sui, Linara S. Axanova, Laura D. Hover, Wendy W. Barclay, Sophia L. Maund
Supplementary Figures 1-9 from Interleukin-1α Mediates the Antiproliferative Effects of 1,25-Dihydroxyvitamin D3 in Prostate Progenitor/Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01699e1d4da083c00673916985f071df
https://doi.org/10.1158/0008-5472.22386459
https://doi.org/10.1158/0008-5472.22386459
Autor:
Scott D. Cramer, Andrew Thorburn, James C. Fleet, Jason D. Hipp, Guangchao Sui, Linara S. Axanova, Laura D. Hover, Wendy W. Barclay, Sophia L. Maund
Supplementary Tables 1-4 from Interleukin-1α Mediates the Antiproliferative Effects of 1,25-Dihydroxyvitamin D3 in Prostate Progenitor/Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f971dec7fec618b6ad853e4ac8e0d6
https://doi.org/10.1158/0008-5472.22386453.v1
https://doi.org/10.1158/0008-5472.22386453.v1
Autor:
Laura Waters, Ruth Aranda, Krystal Moya, Victoria Bowcut, David Trinh, Allan Hebbert, Leo He, Laura D. Hover, Julio Fernandez-Banet, Jill Hallin, David M. Briere, James G. Christensen, Peter A. Olson, Lars D. Engstrom
Publikováno v:
Cancer Research. 83:2779-2779
Previous studies identified PRMT5 as a synthetic lethal target for cancers harboring homozygous deletion of the MTAP gene (MTAP del) whereby accumulation of MTA, the MTAP substrate, partially inhibits PRMT5 activity leading to an increased dependency
Autor:
Mario Suva, Lillian Bussema, Julie Laffy, Michal Slyper, Simon Gritsch, Masashi Nomura, Aviv Regev, Laura D. Hover, Suzanne J. Baker, Itay Tirosh, Chen He
Publikováno v:
Neuro Oncol
High-grade gliomas (HGG) with histone H3.3 G34R mutation are rare intractable tumours in the cerebral hemispheres that preferentially affect adolescents and young adults, but have unknown mechanisms of neuroanatomical specificity and tumourigenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3333938f9ef57291ee4a8c5959aec3
https://europepmc.org/articles/PMC8598547/
https://europepmc.org/articles/PMC8598547/
Autor:
Amar Gajjar, Jinghui Zhang, Yingzhe Wang, Xiaoyan Zhu, William Caufield, Chen He, Xiaoyu Li, Burgess B. Freeman, Zoran Rankovic, Gang Wu, Michelle Monje, Nathaniel R. Twarog, Duane G. Currier, Taosheng Chen, Kimberly S Mercer, Barbara Jonchere, Jason Chiang, Ke Xu, Lawryn H. Kasper, Jia Xie, Laura D. Hover, Ibrahim Qaddoumi, Christopher L. Tinkle, Cynthia Wetmore, Wenwei Lin, Anang A. Shelat, Paul Klimo, Giles W. Robinson, Santhosh A. Upadhyaya, Suzanne J. Baker, Brent A. Orr, Alberto Broniscer, Frederick A. Boop, Paige S. Dunphy, Martine F. Roussel, Paul A. Northcott, Brian Gudenas, Chang-Hyuk Kwon, James T. Dalton, Junyuan Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Pediatric high-grade glioma (pHGG) is a major contributor to cancer-related death in children. In vitro and in vivo disease models reflecting the intimate connection between developmental context and pathogenesis of pHGG are essential to advance unde
Autor:
Chen He, Brian Gudenas, James Dalton, Jason Chiang, Zoran Rankovic, Chang-Hyuk Kwon, Nathaniel R. Twarog, Wenwei Lin, Amar Gajjar, Michelle Monje, Ke Xu, Lawryn H. Kasper, Laura D. Hover, Brent A. Orr, Taosheng Chen, Burgess B. Freeman, Gang Wu, Kimberly S Mercer, Santhosh A. Upadhyaya, Paul Klimo, Yingzhe Wang, Giles W. Robinson, William Caufield, Paige S. Dunphy, Martine F. Roussel, Suzanne J. Baker, Ibrahim Qaddoumi, Cynthia Wetmore, Xiaoyu Li, Jinghui Zhang, Anang A. Shelat, Duane G. Currier, Barbara Jonchere, Christopher L. Tinkle, Paul A. Northcott, Alberto Broniscer, Frederick A. Boop, Junyuan Zhang, Xiaoyan Zhu
Pediatric high-grade glioma (pHGG) is a major contributor to cancer-related death in children.In vitroandin vivodisease models reflecting the intimate connection between developmental context and pathogenesis of pHGG are essential to advance understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50126b367618675b8183d0d1f1bd54c
https://doi.org/10.1101/2020.12.06.407973
https://doi.org/10.1101/2020.12.06.407973