Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Cudd"'
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Providing informed consent for trials requires providing trial participants with comprehensive information about the trial, including information about potential risks and benefits. It is required by the ethical principle of respe
Externí odkaz:
https://doaj.org/article/a8eca9bc899942edb733fc1283c39d66
Publikováno v:
Journal of Zoo and Wildlife Medicine. 32:74-77
Penicillin G and antipyrine, which served as model drugs to assess the relative capacities of renal and hepatic elimination pathways, respectively, were each administered intravenously to six ostriches (Struthio camelus) and to six emus (Dromaius nov
Publikováno v:
American Journal of Veterinary Research. 62:136-141
Objective—To investigate the concentration-dependent effects of Mannheimia haemolytica (formerly Pasteurella haemolytica) leukotoxin (LKT) on apoptosis and oncosis in bovine neutrophils and to examine the role of calcium ions (Ca2+) in LKT-induced
Autor:
Cyril R. Clarke, Laura Cudd, Yude Sun, Sarah K. Highlander, Charlotte L. Ownby, Kenneth D. Clinkenbeard
Publikováno v:
American Journal of Veterinary Research. 61:51-56
Objective—To characterize ultrastructural changes of bovine lymphocytes exposed to Pasteurella haemolytica leukotoxin (LKT). Sample Population—Partially purified LKT from a wild type P haemolytica A1 strain and inactive pro-LKT from an isogeneic
Autor:
Michael Shelton, George L. Murphy, Kenneth D. Clinkenbeard, Cyril R. Clarke, Laura Cudd, Patricia A. Clinkenbeard
Publikováno v:
FEMS Microbiology Letters. 172:123-129
Isolated neutrophils were used to study the intracellular calcium ([Ca2+]i) dependency of Pasteurella haemolytica leukotoxin-induced production of leukotriene B4 and plasma membrane damage. Exposure of neutrophils to leukotoxin caused a rapid and con
Autor:
Yude Sun, Laura Cudd, Sarah K. Highlander, Kenneth D. Clinkenbeard, S. M. Dabo, Cyril R. Clarke
Publikováno v:
Veterinary Microbiology. 65:153-166
It has been reported that Pasteurella haemolytica leukotoxin (LKT) induces morphologic changes in bovine leukocytes consistent with apoptosis in vitro, but DNA fragmentation was not observed. We investigated whether bovine lymphocytes undergo DNA fra
Autor:
Ana Ivanovska, Mengyu Wang, Tarlan Eslami Arshaghi, Georgina Shaw, Joel Alves, Andrew Byrne, Steven Butterworth, Russell Chandler, Laura Cuddy, James Dunne, Shane Guerin, Rob Harry, Aidan McAlindan, Ronan A. Mullins, Frank Barry
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
The recent interest in advanced biologic therapies in veterinary medicine has opened up opportunities for new treatment modalities with considerable clinical potential. Studies with mesenchymal stromal cells (MSCs) from animal species have focused on
Externí odkaz:
https://doaj.org/article/395cd5c9beec4098ab5cd5798dee3429
Publikováno v:
FEMS microbiology letters. 225(1)
The contribution of intracellular calcium stores to Mannheimia haemolytica leukotoxin (LKT)-induced increase in cytosolic calcium concentration was studied by pharmacologically inhibiting transport of calcium across the plasma and endoplasmic reticul
Publikováno v:
FEMS microbiology letters. 224(1)
Isolated bovine neutrophils were used to study the relationship between the duration and magnitude of the Mannheimia haemolytica leukotoxin-induced increase in intracellular calcium concentration and leukotriene B4 synthesis. In contrast to recombina
Publikováno v:
Infection and immunity. 67(12)
Pasteurella haemolytica , the causative agent of shipping fever pneumonia in cattle, produces a leukotoxin (LKT) which lyses ruminant leukocytes with high efficiency but is reputed to not affect leukocytes from nonruminant species. In this study, we