Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Laura Coch"'
Autor:
Santiago Ramon y Cajal, Inés de Torres, Javier Hernández-Losa, Matilde Lleonart, Elisabet Argelaguet, Laura Coch, Berta Pons, Gemma Armengol, Laura López-Vicente
Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8726971fef44bdce535efa03e6ac9a03
https://doi.org/10.1158/1078-0432.22439952
https://doi.org/10.1158/1078-0432.22439952
Autor:
Santiago Ramon y Cajal, Inés de Torres, Javier Hernández-Losa, Matilde Lleonart, Elisabet Argelaguet, Laura Coch, Berta Pons, Gemma Armengol, Laura López-Vicente
Purpose: The control of senescence and its biochemical pathways is a crucial factor for understanding cell transformation. In a large RNA interference screen, the RSK4 gene was found to be related to p53-dependent arrest. The purpose of the present s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2ecd49b49f2a9bf1b97191d0ba71d3
https://doi.org/10.1158/1078-0432.c.6517335.v1
https://doi.org/10.1158/1078-0432.c.6517335.v1
Autor:
Marc Mejias, Ester Garcia-Pras, Laura Coch, Jaime Bosch, Javier Gallego, Mercedes Fernandez, Raúl Méndez, Annalisa Berzigotti
Publikováno v:
Hepatology. 60:633-647
Pathological angiogenesis represents a critical hallmark for chronic liver diseases. Understanding the mechanisms regulating angiogenesis is essential to develop new therapeutic strategies that specifically target pathological angiogenesis without af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223ab65dabc0e11104121d0f84030384
https://doi.org/10.1002/hep.26995
https://doi.org/10.1002/hep.26995
Autor:
Jaime Bosch, Javier Gallego, Ester Garcia-Pras, Marc Mejias, Laura Coch, Mercedes Fernandez, Annalisa Berzigotti
Publikováno v:
Gut. 64:657-666
Objective Antiangiogenic strategies have been proposed as a promising new approach for the therapy of portal hypertension and chronic liver disease. Pigment epithelium-derived factor (PEDF) is a powerful endogenous angiogenesis inhibitor whose role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ead4ce1c0e50787ccc24688ee912800
https://doi.org/10.1136/gutjnl-2014-307138
https://doi.org/10.1136/gutjnl-2014-307138
Autor:
Gonzalo Fernández-Miranda, Jaime Bosch, Mercedes Fernandez, Ester Garcia-Pras, Raúl Méndez, Javier Gallego, Ricardo Pardal, Marc Mejias, Laura Coch
Publikováno v:
Gut. 66(7)
Objective Pathological neovascularisation is intimately involved in portal hypertension (PH). Here, we determined the contribution of vascular stem/progenitor cells (VSPCs) to neovessel growth in PH and whether the RNA-binding protein cytoplasmic pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1f9cf794002d3c4b077e5f51199810
https://pubmed.ncbi.nlm.nih.gov/26984852
https://pubmed.ncbi.nlm.nih.gov/26984852
Autor:
Camille Stephan-Otto Attolini, Ivan Garcia-Bassets, Oscar Reina, Roman Kessler, Laura Coch, Fernando Azorín, Joan Font-Burgada, Johan Tisserand
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
© 2015 Macmillan Publishers Limited. All rights reserved. dDsk2 is a conserved extraproteasomal ubiquitin receptor that targets ubiquitylated proteins for degradation. Here we report that dDsk2 plays a nonproteolytic function in transcription regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f205b56f5e720b4d11844692e5678b
https://pubmed.ncbi.nlm.nih.gov/25916810
https://pubmed.ncbi.nlm.nih.gov/25916810
Autor:
María Ángeles Vázquez-Sánchez, Elisabet Argelaguet, Laura Coch, Berta Pons, Laura López-Vicente, A. Martínez, Gemma Armengol, Vicente Peg, Santiago Ramón y Cajal, Javier Hernández-Losa
Publikováno v:
International Journal of Oncology.
Cell signaling pathways and protein translation are crucial for understanding malignant transformation. 4E-BP1 and the eIF4F complex regulate cap-dependent translation. We investigated how 4E-BP1 and eIF4E phosphorylation status affects in vitro and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac5ea112a021b01c83b3a4827ea1d61
https://doi.org/10.3892/ijo.2011.1118
https://doi.org/10.3892/ijo.2011.1118
Autor:
Santiago Ramón y Cajal, Laura Coch, Laura Cecilia López, Gemma Armengol, Mark Livingstone, Berta Pons, Nahum Sonenberg
Publikováno v:
Oncology reports. 27(1)
Translational control is a crucial component of cancer development and progression. Eukaryotic initiation factor (eIF) 4E mediates eIF4F association with the mRNA 5' cap structure to stimulate cap-dependent translation initiation. The eIF4E-binding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168984c7355391b47de98b52461727eb
https://pubmed.ncbi.nlm.nih.gov/21922152
https://pubmed.ncbi.nlm.nih.gov/21922152
Autor:
Laura Coch, Santiago Ramón y Cajal, Laura López-Vicente, Cristina Teixidó, Gemma Armengol, Berta Pons, Javier Hernández-Losa
Publikováno v:
Carcinogenesis. 32(4)
p90 Ribosomal S6 kinase (RSK) 4 is a serine―threonine kinase that belongs to the p90RSK family. RSK4 has been proposed as a tumor suppressor gene, related with anti-invasive activity, inhibition of the RAS―mitogen-activated protein kinase (MAPK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310326f4b1dfde0466bbddc2362ffb86
https://pubmed.ncbi.nlm.nih.gov/21239520
https://pubmed.ncbi.nlm.nih.gov/21239520
Autor:
Mejias, Marc, Coch, Laura, Berzigotti, Annalisa, Garcia-Pras, Ester, Gallego, Javier, Bosch, Jaime, Fernandez, Mercedes
Publikováno v:
Gut; Apr2015, Vol. 64 Issue 4, p657-666, 10p, 1 Chart, 4 Graphs