Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Laura Clifton‐Hadley"'
Results from UKALL60+, a phase 2 study in older patients with untreated acute lymphoblastic leukemia
Autor:
Bela Patel, Amy A. Kirkwood, Clare J. Rowntree, Krisztina Z. Alapi, Emilio Barretta, Laura Clifton‐Hadley, Tom Creasey, SooWah Lee, David I. Marks, Anthony V. Moorman, Nicholas Morley, Pip Patrick, Zaynab Rana, Anita Rijneveld, John A. Snowden, Adele K. Fielding
Publikováno v:
HemaSphere, Vol 8, Iss 6, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/f8ed0d4f316040aaadab89e48c475ad0
Autor:
John Radford, Toyin Adedayo, Arzhang Ardavan, Sally F. Barrington, Leanne Berkahn, Stephane Chauvie, Laura Clifton-Hadley, Graham P. Collins, Michael Crump, David Cutter, Darren Edwards, Martin Hutchings, Tim Illidge, Amy A. Kirkwood, Kim Linton, Craig H. Moskowitz, Pip Patrick, Beth Phillips, Lois Shepherd, Sanne Tonino, Judith Trotman, Joanna Williams, Nicole Wong Doo
Publikováno v:
HemaSphere, Vol 6, Pp 12-13 (2022)
Externí odkaz:
https://doaj.org/article/d506da6863614fcc9905cf968405f6fe
Autor:
Elizabeth H. Phillips, Catherine Burton, Amy A. Kirkwood, Sharon Barrans, Anthony Lawrie, Simon Rule, Russell Patmore, Ruth Pettengell, Kirit M. Ardeshna, Silvia Montoto, Shankara Paneesha, Laura Clifton‐Hadley, David C. Linch, Andrew K. McMillan
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 133-141 (2020)
Abstract Introduction Outcomes after frontline treatment of Burkitt lymphoma (BL) have improved with the introduction of dose‐intense chemotherapy regimens, such as CODOX‐M/IVAC. While rituximab has increased survival rates for most forms of high
Externí odkaz:
https://doaj.org/article/672485bdf8ef4a628ec33ee2f4ce939a
Autor:
Tim M. Illidge, Elizabeth H. Phillips, Nicholas Counsell, Ruth Pettengell, Peter W.M. Johnson, Dominic J. Culligan, Bilyana Popova, Laura Clifton-Hadley, Andrew McMillan, Peter Hoskin, Sally F. Barrington, John Radford
Publikováno v:
Blood Advances, Vol 4, Iss 1, Pp 203-206 (2020)
Externí odkaz:
https://doaj.org/article/22a017ba18324963a873caf2b7ad3390
Autor:
Emma Das-Gupta, Kirsty J. Thomson, Adrian J.C. Bloor, Andrew D. Clark, Stephen Mackinnon, Irfan Kayani, Laura Clifton-Hadley, Pip Patrick, Nadjet El-Mehidi, Anthony Lawrie, Amy A. Kirkwood, Nigel H. Russell, David C. Linch, Karl S. Peggs
Publikováno v:
Blood Advances, Vol 3, Iss 24, Pp 4264-4270 (2019)
Abstract: We evaluated the role of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in transplant-naïve patients with relapsed/refractory Hodgkin lymphoma (HL) who failed to attain metabolic complete response (mCR) to 1 to 2 lines of s
Externí odkaz:
https://doaj.org/article/fcbef3681889418ebbc0e8a61fd4114f
Autor:
Thomas Creasey, Emilio Barretta, Sarra L. Ryan, Ellie Butler, Amy A. Kirkwood, Daniel Leongamornlert, Elli Papaemmanuil, Pip Patrick, Laura Clifton-Hadley, Bela Patel, Tobias Menne, Andrew K. McMillan, Christine J. Harrison, Clare J. Rowntree, Nick Morley, David I. Marks, Adele K. Fielding, Anthony V. Moorman
Publikováno v:
Haematologica, Vol 107, Iss 9 (2021)
Despite being predominantly a childhood disease, the incidence of acute lymphoblastic leukemia (ALL) has a second peak in adults aged 60 years and over. These older adults fare extremely poorly with existing treatment strategies and very few studies
Externí odkaz:
https://doaj.org/article/8a04be27587840df8c9f2b5d4ebd7f27
Autor:
Colin Watts, Keyoumars Ashkan, Michael D. Jenkinson, Stephen J. Price, Thomas Santarius, Tomasz Matys, Ting Ting Zhang, Alina Finch, Peter Collins, Kieren Allinson, Sarah J. Jefferies, Daniel J. Scoffings, Athanasios Zisakis, Mark Phillips, Katharina Wanek, Paul Smith, Laura Clifton-Hadley, Nicholas Counsell
Publikováno v:
Cancers, Vol 13, Iss 13, p 3241 (2021)
Background Glioblastoma (GBM) is the commonest primary malignant brain tumour in adults and effective treatment options are limited. Combining local chemotherapy with enhanced surgical resection using 5-aminolevulinic acid (5-ALA) could improve outco
Externí odkaz:
https://doaj.org/article/106f56619c9e40e080fcc96e8ef1b5e5
Autor:
Nicholas Brown, Catherine McBain, Stephen Nash, Kirsten Hopkins, Paul Sanghera, Frank Saran, Mark Phillips, Fiona Dungey, Laura Clifton-Hadley, Katharina Wanek, Daniel Krell, Sarah Jeffries, Iftekhar Khan, Paul Smith, Paul Mulholland
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156369 (2016)
Cediranib, an oral pan-vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor, failed to show benefit over lomustine in relapsed glioblastoma. One resistance mechanism for cediranib is up-regulation of epidermal growth factor re
Externí odkaz:
https://doaj.org/article/869ae0c70c984db6a700441a9ac2da50
Autor:
Kwee Yong, William Wilson, Ruth M de Tute, Marquita Camilleri, Karthik Ramasamy, Matthew Streetly, Jonathan Sive, Ceri A Bygrave, Reuben Benjamin, Michael Chapman, Selina J Chavda, Elizabeth H Phillips, Maria del Mar Cuadrado, Gavin Pang, Richard Jenner, Tushhar Dadaga, Sumaiya Kamora, James Cavenagh, Laura Clifton-Hadley, Roger G Owen, Rakesh Popat
Publikováno v:
The Lancet Haematology. 10:e93-e106
Standard-of-care treatment for patients with newly diagnosed multiple myeloma is bortezomib-based induction followed by high-dose melphalan and autologous haematopoietic stem-cell transplantation (HSCT) and lenalidomide maintenance. We aimed to evalu
Autor:
Karl S. Peggs, Sarah J. Albon, Macarena Oporto Espuelas, Catherine Irving, Rachel Richardson, Joan Casanovas-Company, Rebecca Wallace, Aleks Guvenel, Sara Ghorashian, Angela Collura, Meera Subramaniyam, Barry Flutter, Bilyana Popova, Fernanda Castro, Andre Lopes, Kim Champion, Oliver Schofield, Laura Clifton-Hadley, Thomas Taylor, Maria Farrell, Stuart Adams, Kimberly C. Gilmour, Stephen Mackinnon, Eleni Tholouli, Persis J. Amrolia
Publikováno v:
Cytotherapy. 25:82-93
Delayed immune reconstitution is a major challenge after matched unrelated donor (MUD) stem cell transplant (SCT). In this randomized phase 2 multi-center trial, Adoptive Immunotherapy with CD25/71 allodepleted donor T cells to improve immunity after