Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Ciucchi"'
Autor:
Riccardo Barrile, Marina de Bernard, Beatrice Aricò, Alessandro Casellato, Laura Ciucchi, Mariagrazia Pizza, Fleur Bossi, Gaia Codolo, Silvia Rossi Paccani
Publikováno v:
Cellular Microbiology. 16:925-937
Neisseria meningitidis is a human pathogen that can cause fatal sepsis and meningitis once it reaches the blood stream and the nervous system. Here we demonstrate that a fragment, released upon proteolysis of the surface-exposed protein Neisserial He
Autor:
Alessandro Casellato, Silvia Rossi Paccani, Riccardo Barrile, Laura Ciucchi, Gaia Codolo, Mariagrazia Pizza, Beatrice Aricò, Marina de Bernard, BOSSI, FLEUR
Neisseria meningitidis is a human pathogen that can cause fatal sepsis and meningitis once it reaches the blood stream and the nervous system. Here we demonstrate that a fragment, released upon proteolysis of the surface-exposed protein Neisserial He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c755284f219191a2c2b2b220eff13119
http://hdl.handle.net/11577/2741878
http://hdl.handle.net/11577/2741878
Autor:
Scilla Buccato, Marco Becherelli, Elisa Viciani, Laura Ciucchi, Guido Grandi, Andrea G. O. Manetti, Giulia Mollica, Imma Margarit
Publikováno v:
Molecular Microbiology
Summary Gram-positive pili are known to play a role in bacterial adhesion to epithelial cells and in the formation of biofilm microbial communities. In the present study we undertook the functional characterization of the pilus ancillary protein 1 (A
Autor:
Mariagrazia Pizza, Riccardo Barrile, Rino Rappuoli, Michele Sallese, Giuseppe Bozza, Paolo Montanari, Mirco Capitani, Laura Ciucchi, Zhenai Gao, Barbara Capecchi, Elena Caproni, Nathalie Norais, Marcello Merola, Paola Cecchini, Beatrice Aricò
Publikováno v:
Cellular Microbiology. 14:368-385
NadA (N eisseria meningitidisadhesin A), a meningococcal surface protein, mediates adhesion to and invasion of human cells, an activity in which host membrane proteins have been implicated. While investigating these host factors in human epithelial c
Autor:
Davide Serruto, Brunella Brunelli, Rino Rappuoli, Laura Santini, Elena Cartocci, Dan M. Granoff, Federica Di Marcello, Mario Contorni, Alessia Biolchi, Beatrice Aricò, Jeannette Adu-Bobie, Jo Anne Welsch, Donatella Mannucci, Daniele Veggi, Francesca Titta, Alessandro Bartalesi, Vanda Cinotti, Mariagrazia Pizza, Stefania Bambini, Barbara Capecchi, Maurizio Morandi, Vega Masignani, Elisa Ovidi, Laura Ciucchi, Francesca Ferlicca, Barbara Galli, Marzia Monica Giuliani, Enrico Luzzi, Silvana Savino, Maurizio Comanducci
Publikováno v:
Proceedings of the National Academy of Sciences. 103:10834-10839
Meningitis and sepsis caused by serogroup B meningococcus are two severe diseases that still cause significant mortality. To date there is no universal vaccine that prevents these diseases. In this work, five antigens discovered by reverse vaccinolog
Autor:
Rino Rappuoli, Beatrice Aricò, Mariagrazia Pizza, Barbara Capecchi, Annarita Taddei, Laura Ciucchi, Vega Masignani, Jeannette Adu-Bobie, Federica Di Marcello
Publikováno v:
Molecular Microbiology. 55:687-698
Neisseria meningitidis is a human pathogen, which is a major cause of sepsis and meningitis. The bacterium colonizes the upper respiratory tract of approximately 10% of humans where it lives as a commensal. On rare occasions, it crosses the epitheliu
Autor:
Paolo, Montanari, Giuseppe, Bozza, Barbara, Capecchi, Elena, Caproni, Riccardo, Barrile, Nathalie, Norais, Mirco, Capitani, Michele, Sallese, Paola, Cecchini, Laura, Ciucchi, Zhenai, Gao, Rino, Rappuoli, Mariagrazia, Pizza, Beatrice, Aricò, Marcello, Merola
Publikováno v:
Cellular microbiology. 14(3)
NadA (N eisseria meningitidisadhesin A), a meningococcal surface protein, mediates adhesion to and invasion of human cells, an activity in which host membrane proteins have been implicated. While investigating these host factors in human epithelial c
Autor:
Barbara Brogioni, Marzia Monica Giuliani, Daniele Veggi, Maurizio Comanducci, Beatrice Aricò, Michele Pallaoro, Enrico Malito, Paola Lo Surdo, Silvana Savino, Annalisa Colaprico, Maria Scarselli, Patrizia Giannetti, Lucia Banci, Francesco Doro, Francesca Cantini, Marta Tontini, Brunella Brunelli, Mariagrazia Pizza, Elena Cartocci, Markus Hilleringmann, Rino Rappuoli, Sara Dragonetti, Matthew J. Bottomley, Federica Di Marcello, Laura Ciucchi, Vincenzo Nardi-Dei, Emmanuelle Palumbo
Publikováno v:
Science translational medicine. 3(91)
The sequence variability of protective antigens is a major challenge to the development of vaccines. For Neisseria meningitidis, the bacterial pathogen that causes meningitis, the amino acid sequence of the protective antigen factor H binding protein
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans
Autor:
Lisa A. Lewis, Andrew G. Plaut, J. Simon Kroll, Maria Scarselli, Clíona A. O'Dwyer, Tiziana Spadafina, John J. Donnelly, Mariagrazia Pizza, Alessia Biolchi, Paolo Costantino, Rino Rappuoli, Laura Santini, Laura Ciucchi, Beatrice Aricò, Marta Tontini, Francesco Berti, Silvana Savino, Jiazhou Qiu, Sanjay Ram, Davide Serruto, Marzia Monica Giuliani, Kate L. Seib, Richard Moxon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(8)
GNA2132 is a Neisseria meningitidis antigen of unknown function, discovered by reverse vaccinology, which has been shown to induce bactericidal antibodies in animal models. Here we show that this antigen induces protective immunity in humans and it i
Autor:
Laura Ciucchi, Stefania Bambini, Mariagrazia Pizza, Rino Rappuoli, Marirosa Mora, Brunella Brunelli, Dominique A. Caugant, Maurizio Comanducci, Barbara Capecchi
Publikováno v:
Infection and immunity. 72(7)
NadA is a novel vaccine candidate recently identified in Neisseria meningitidis and involved in adhesion to host tissues. The nadA gene has been found in approximately 50% of the strains isolated from patients and in three of the four hypervirulent l