Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Laura Ciapponi"'
Autor:
Marta Marzullo, Giulia Romano, Claudia Pellacani, Federico Riccardi, Laura Ciapponi, Fabian Feiguin
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Aging progressively modifies the physiological balance of the organism increasing susceptibility to both genetic and sporadic neurodegenerative diseases. These changes include epigenetic chromatin remodeling events that may modify the transc
Externí odkaz:
https://doaj.org/article/2c9671d0f1a648cab0695a9eae1dee4e
Autor:
Nina Strah, Giulia Romano, Clelia Introna, Raffaella Klima, Marta Marzullo, Laura Ciapponi, Aram Megighian, Monica Nizzardo, Fabian Feiguin
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background The ribonuclear protein TDP-43 has been implicated in the pathophysiology of amyotrophic lateral sclerosis (ALS), with genetic mutations being linked to the neurological symptoms of the disease. Though alterations in the intracell
Externí odkaz:
https://doaj.org/article/8342709f5ed845b59ab7ba86eb69f58b
Autor:
Sonia Coni, Federica A Falconio, Marta Marzullo, Marzia Munafò, Benedetta Zuliani, Federica Mosti, Alessandro Fatica, Zaira Ianniello, Rosa Bordone, Alberto Macone, Enzo Agostinelli, Alessia Perna, Tanja Matkovic, Stephan Sigrist, Gabriella Silvestri, Gianluca Canettieri, Laura Ciapponi
Publikováno v:
eLife, Vol 10 (2021)
Microsatellite expansions of CCTG repeats in the cellular nucleic acid-binding protein (CNBP) gene leads to accumulation of toxic RNA and have been associated with myotonic dystrophy type 2 (DM2). However, it is still unclear whether the dystrophic p
Externí odkaz:
https://doaj.org/article/e2297eac8cb54bc882d8e8ccac2b6c5b
Autor:
Paolo Maccallini, Francesca Bavasso, Livia Scatolini, Elisabetta Bucciarelli, Gemma Noviello, Veronica Lisi, Valeria Palumbo, Simone D'Angeli, Stefano Cacchione, Giovanni Cenci, Laura Ciapponi, James G Wakefield, Maurizio Gatti, Grazia Daniela Raffa
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008815 (2020)
Trimethylguanosine synthase 1 (TGS1) is a conserved enzyme that mediates formation of the trimethylguanosine cap on several RNAs, including snRNAs and telomerase RNA. Previous studies have shown that TGS1 binds the Survival Motor Neuron (SMN) protein
Externí odkaz:
https://doaj.org/article/6068dac10ba64033b50cebbe66a307f8
Autor:
Romina Burla, Mariateresa Carcuro, Grazia D Raffa, Alessandra Galati, Domenico Raimondo, Angela Rizzo, Mattia La Torre, Emanuela Micheli, Laura Ciapponi, Giovanni Cenci, Enrico Cundari, Antonio Musio, Annamaria Biroccio, Stefano Cacchione, Maurizio Gatti, Isabella Saggio
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005167 (2015)
Telomeres are nucleoprotein complexes that protect the ends of linear chromosomes from incomplete replication, degradation and detection as DNA breaks. Mammalian telomeres are protected by shelterin, a multiprotein complex that binds the TTAGGG telom
Externí odkaz:
https://doaj.org/article/ec2e1ff22daf46b2bdc27d8bf028cd96
Autor:
Giovanni Cenci, Laura Ciapponi, Marta Marzullo, Grazia D Raffa, Patrizia Morciano, Domenico Raimondo, Romina Burla, Isabella Saggio, Maurizio Gatti
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005260 (2015)
Drosophila telomeres are sequence-independent structures that are maintained by transposition to chromosome ends of three specialized retroelements (HeT-A, TART and TAHRE; collectively designated as HTT) rather than telomerase activity. Fly telomeres
Externí odkaz:
https://doaj.org/article/400af8edae434acd8a06858ff309bbeb
Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference.
Autor:
Maria Patrizia Somma, Francesca Ceprani, Elisabetta Bucciarelli, Valeria Naim, Valeria De Arcangelis, Roberto Piergentili, Antonella Palena, Laura Ciapponi, Maria Grazia Giansanti, Claudia Pellacani, Romano Petrucci, Giovanni Cenci, Fiammetta Vernì, Barbara Fasulo, Michael L Goldberg, Ferdinando Di Cunto, Maurizio Gatti
Publikováno v:
PLoS Genetics, Vol 4, Iss 7, p e1000126 (2008)
RNAi screens have, to date, identified many genes required for mitotic divisions of Drosophila tissue culture cells. However, the inventory of such genes remains incomplete. We have combined the powers of bioinformatics and RNAi technology to detect
Externí odkaz:
https://doaj.org/article/105f6f6d5f2040ef90cdcfcf5805612c
Autor:
Rosy Sakr, Pierre B. Cattenoz, Alexia Pavlidaki, Laura Ciapponi, Marta Marzullo, Nivedita Hariharan, Tina Mukherjee, Angela Giangrande
Cell types can be now defined at unprecedented resolution using high throughput assays. We analyzed the transcriptional signatures of Drosophila neurons, glia and hemocytes, as examples of cell types that are related by position (glia/neurons) or fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40731ddd7ccc5a44308368cb10c7afcf
https://hal.science/hal-03797237/file/2022.06.30.498263v1.full.pdf
https://hal.science/hal-03797237/file/2022.06.30.498263v1.full.pdf
Autor:
Chiara D’Ercole, Paolo D’Angelo, Veronica Ruggieri, Daisy Proietti, Laura Virtanen, Cristina Parisi, Carles Sanchez Riera, Alessandra Renzini, Alberto Macone, Marta Marzullo, Laura Ciapponi, Davide Bonvissuto, Claudio Sette, Lorenzo Giordani, Luca Madaro
Striated muscle is a highly organized structure composed of well-defined anatomical domains with integrated but distinct assignments. So far, the lack of a direct correlation between tissue architecture and gene expression has limited our understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01c899847cabbf32e88487fcc0ececa
https://hdl.handle.net/11573/1662908
https://hdl.handle.net/11573/1662908
Autor:
Benedetta Zuliani, Zaira Ianniello, Alessandro Fatica, Marta Marzullo, Alberto Macone, Alessia Perna, Rosa Bordone, Gabriella Silvestri, Marzia Munafò, Tanja Matkovic, Enzo Agostinelli, Stephan J. Sigrist, Federica A Falconio, Sonia Coni, Federica Mosti, Laura Ciapponi, Gianluca Canettieri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dbec7de4bc0ebf02cd83801c532f525
https://doi.org/10.7554/elife.69269.sa2
https://doi.org/10.7554/elife.69269.sa2