Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura Ciaccia West"'
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e51343 (2013)
Gamma-interferon-inducible lysosomal thiol reductase (GILT) is known to reduce disulfide bonds present in proteins internalized by antigen presenting cells, facilitating optimal processing and presentation of peptides on Major Histocompatibility Comp
Externí odkaz:
https://doaj.org/article/3cfdb91a197a4ca4b7c53a12e7d967c2
Autor:
Bing Shuai, Ashok K. Shetty, Maheedhar Kodali, Laura Ciaccia West, Robert Dantzer, Thien Trong Phan, Joshua D. Bryant, Paige J. Graves, Saeed S. Menissy, A. Phillip West
Publikováno v:
Brain Behav Immun
Gulf War Illness (GWI) is a chronic, multi-symptom disorder affecting approximately 30 percent of the nearly 700,000 Veterans of the 1991 Persian Gulf War. GWI-related chemical (GWIC) exposure promotes immune activation that correlates with cognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ebad551c6134e90e70000dd066ce53
https://doi.org/10.1016/j.bbi.2021.07.015
https://doi.org/10.1016/j.bbi.2021.07.015
Autor:
Yuanjiu Lei, Jordyn J. VanPortfliet, Yi-Fan Chen, Joshua D. Bryant, Ying Li, Danielle Fails, Sylvia Torres-Odio, Katherine B. Ragan, Jingti Deng, Armaan Mohan, Bing Wang, Olivia N. Brahms, Shawn D. Yates, Michael Spencer, Carl W. Tong, Marcus W. Bosenberg, Laura Ciaccia West, Gerald S. Shadel, Timothy E. Shutt, Jason W. Upton, Pingwei Li, A. Phillip West
SUMMARYMitochondrial DNA (mtDNA) is a potent agonist of the innate immune system; however, the exact immunostimulatory features of mtDNA and the kinetics of mtDNA detection by cytosolic nucleic acid sensors remain poorly defined. Here, we show that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40762d17c3bc167f537854a7fe731c1b
https://doi.org/10.1101/2022.05.30.493783
https://doi.org/10.1101/2022.05.30.493783
Autor:
A. Phillip West, Robert O. Watson, Camila Guerra Martinez, Joshua D. Bryant, Sylvia Torres-Odio, Samantha L. Bell, Yuanjiu Lei, Carl W. Tong, Christine E. Birdwell, Laura Ciaccia West
Publikováno v:
Science Advances. 7
Mitochondrial dysfunction is a key driver of inflammatory responses in human disease. However, it remains unclear whether alterations in mitochondria-innate immune cross-talk contribute to the pathobiology of mitochondrial disorders and aging. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7108e75f2d535be54d4f32994e544b20
https://doi.org/10.1126/sciadv.abe7548
https://doi.org/10.1126/sciadv.abe7548
Autor:
Saeed S. Menissy, A. Phillip West, Laura Ciaccia West, Ashok K. Shetty, Maheedhar Kodali, Bing Shuai, Paige J. Graves, Joshua D. Bryant
Gulf War Illness (GWI) is a chronic, multi-symptom disorder affecting approximately 30 percent of the nearly 700,000 veterans of the 1991 Persian Gulf War. Recent studies have revealed that GWI-related chemical (GWIC) exposure promotes immune activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df994e042107600fe8b9ea6dcc51d542
https://doi.org/10.1101/2020.08.28.271833
https://doi.org/10.1101/2020.08.28.271833
Autor:
Laura Ciaccia West, Peter Cresswell
Publikováno v:
Current Opinion in Immunology. 25:103-108
Gamma-interferon-inducible lysosomal thiol reductase (GILT), a thioredoxin-related oxidoreductase, functions in MHC class II-restricted antigen processing and MHC class I-restricted cross-presentation by reducing disulfide bonds of endocytosed protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af5e0588385a77e7811109c3c558dc3
https://doi.org/10.1016/j.coi.2012.11.006
https://doi.org/10.1016/j.coi.2012.11.006
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e51343 (2013)
PLoS ONE
PLoS ONE
Gamma-interferon-inducible lysosomal thiol reductase (GILT) is known to reduce disulfide bonds present in proteins internalized by antigen presenting cells, facilitating optimal processing and presentation of peptides on Major Histocompatibility Comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252493c2fa3609590d7e4ff631c3e3d1
https://doi.org/10.1371/journal.pone.0051343
https://doi.org/10.1371/journal.pone.0051343