Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Laura Ciacchi"'
Autor:
Jan Petersen, Hugh H. Reid, Laura Ciacchi, Melinda Y Hardy, Frits Koning, Robert P. Anderson, Khai Lee Loh, Yvonne Kooy-Winkelaar, Jason A. Tye-Din, Anthony W. Purcell, Zhenjun Chen, Jamie Rossjohn, James McCluskey, Mai T. Tran, Nathan P. Croft
Publikováno v:
Nature Structural and Molecular Biology. NATURE PUBLISHING GROUP
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology
Structural, biochemical and cellular analyses show that bacterial antigens can mimic gliadin epitopes involved in celiac disease being presented by HLA-DQ2.5 and recognized by T cells derived from patients.The human leukocyte antigen (HLA) locus is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abfd599d8b19bafaf0dfa39cb73754c
https://doi.org/10.1038/s41594-019-0353-4
https://doi.org/10.1038/s41594-019-0353-4
Autor:
Laura Ciacchi, Carine Farenc, Shiva Dahal-Koirala, Jan Petersen, Ludvig M. Sollid, Hugh H. Reid, Jamie Rossjohn
Publikováno v:
The Journal of biological chemistry. 298(3)
Celiac disease is a T cell-mediated chronic inflammatory condition often characterized by human leukocyte antigen (HLA)-DQ2.5 molecules presenting gluten epitopes derived from wheat, barley, and rye. Although some T cells exhibit cross-reactivity tow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c333062e87c5ea0d31dd068f855a1b5
https://pubmed.ncbi.nlm.nih.gov/35065967
https://pubmed.ncbi.nlm.nih.gov/35065967
Publikováno v:
Current Opinion in Structural Biology. 74:102349
Celiac disease (CeD) is a human leukocyte antigen (HLA)-linked autoimmune-like disorder that is triggered by the ingestion of gluten or related storage proteins. The majority of CeD patients are HLA-DQ2.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3f4efa7a56ba45e11397691a5edb8e
https://doi.org/10.1016/j.sbi.2022.102349
https://doi.org/10.1016/j.sbi.2022.102349
Autor:
Jan, Petersen, Laura, Ciacchi, Mai T, Tran, Khai Lee, Loh, Yvonne, Kooy-Winkelaar, Nathan P, Croft, Melinda Y, Hardy, Zhenjun, Chen, James, McCluskey, Robert P, Anderson, Anthony W, Purcell, Jason A, Tye-Din, Frits, Koning, Hugh H, Reid, Jamie, Rossjohn
Publikováno v:
Nature structuralmolecular biology. 27(1)
The human leukocyte antigen (HLA) locus is strongly associated with T cell-mediated autoimmune disorders. HLA-DQ2.5-mediated celiac disease (CeD) is triggered by the ingestion of gluten, although the relative roles of genetic and environmental risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77b583f34c66ed71f8c19f044df94131
https://pubmed.ncbi.nlm.nih.gov/31873302
https://pubmed.ncbi.nlm.nih.gov/31873302