Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Laura Chopp"'
Publikováno v:
Bio-Protocol, Vol 8, Iss 23 (2018)
To track recent thymic emigrants (RTEs) or study T cell development in the thymus, intra-thymic injection of a cellular tag or precursor cells for various T cell lineages is often desired. However, the traditional surgical approach to expose the thym
Externí odkaz:
https://doaj.org/article/a0ec4a70971945d293f7bda9c782d8ad
Autor:
Tasha A. Morrison, Rachael Philips, Jaelyn Vigee, Laura Chopp, Hiroyuki Nagashima, Giuseppe Sciumè, Yuka Kanno, John J. O’Shea
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2253449eb9ef794636000e1018bd18f8
https://doi.org/10.1016/b978-0-12-821618-7.00253-4
https://doi.org/10.1016/b978-0-12-821618-7.00253-4
Publikováno v:
The Journal of allergy and clinical immunology. 151(1)
T cells are critical orchestrators of the adaptive immune response that optimally eliminate a specific pathogen. Aberrant T-cell development and function are implicated in a broad range of human disease including immunodeficiencies, autoimmune diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a89385952d98c0e6e35904f36dced9
https://pubmed.ncbi.nlm.nih.gov/36272581
https://pubmed.ncbi.nlm.nih.gov/36272581
Autor:
Yayi Gao, Monica Zamisch, Melanie Vacchio, Laura Chopp, Thomas Ciucci, Elliott L. Paine, Gaelyn C. Lyons, Jia Nie, Qi Xiao, Ekaterina Zvezdova, Paul E. Love, Charles R. Vinson, Lisa M. Jenkins, Rémy Bosselut
Publikováno v:
Sci Immunol
Although BTB–zinc finger (BTB-ZF) transcription factors control the differentiation of multiple hematopoietic and immune lineages, how they function is poorly understood. The BTB-ZF factor Thpok controls intrathymic CD4 + T cell development and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26e1b8aac03609cfc9dbed3bd3435b4
https://europepmc.org/articles/PMC9484726/
https://europepmc.org/articles/PMC9484726/
Autor:
Yongbing Zhao, Supriya V. Vartak, Andrea Conte, Xiang Wang, David A. Garcia, Evan Stevens, Seol Kyoung Jung, Kyong-Rim Kieffer-Kwon, Laura Vian, Timothy Stodola, Francisco Moris, Laura Chopp, Silvia Preite, Pamela L. Schwartzberg, Joseph M. Kulinski, Ana Olivera, Christelle Harly, Avinash Bhandoola, Elisabeth F. Heuston, David M. Bodine, Raul Urrutia, Arpita Upadhyaya, Matthew T. Weirauch, Gordon Hager, Rafael Casellas
Publikováno v:
Molecular cell. 82(18)
Regulatory elements activate promoters by recruiting transcription factors (TFs) to specific motifs. Notably, TF-DNA interactions often depend on cooperativity with colocalized partners, suggesting an underlying cis-regulatory syntax. To explore TF c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3aa7283a073e3f8e1086eef862cab3f
https://pubmed.ncbi.nlm.nih.gov/35863348
https://pubmed.ncbi.nlm.nih.gov/35863348
Autor:
Yayi Gao, Monica Zamisch, Melanie S Vacchio, Elliott Paine, Gaelyn Lyons, Thomas Ciucci, Laura Chopp, Qi Xiao, Charles Vinson, Lisa Jenkins, Rémy Bosselut
Publikováno v:
The Journal of Immunology. 206:108.10-108.10
T cell precursors develop into helper CD4 or cytotoxic CD8 T cells in thymus. Thpok, a BTB/POZ family transcription factor, enforces MHC II restricted thymocytes commitment to the CD4 lineage, while Runx3 protein drives MHC I restricted thymocytes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::915cb054ac1c833704bddbad3a912dc3
https://doi.org/10.4049/jimmunol.206.supp.108.10
https://doi.org/10.4049/jimmunol.206.supp.108.10
Autor:
Brendan Reed, Laura Chopp, Megan Girtman, Virginia Van Keulen, Aaron Johnson, Adam Schrum, Larry Pease
Publikováno v:
The Journal of Immunology. 192:69.27-69.27
MHC multimers including tetramers and pentamers provide a powerful way to visualize antigen specific T cell responses in both experimental and clinical immune assays. The multimers can be acquired commercially, from the NIH, or assembled in the labor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b65f631aeed5b85263a3cee8d6a1e513
https://doi.org/10.4049/jimmunol.192.supp.69.27
https://doi.org/10.4049/jimmunol.192.supp.69.27
Autor:
Gao, Yayi, Zamisch, Monica, Vacchio, Melanie, Chopp, Laura, Ciucci, Thomas, Paine, Elliott L., Lyons, Gaelyn C., Nie, Jia, Xiao, Qi, Zvezdova, Ekaterina, Love, Paul E., Vinson, Charles R., Jenkins, Lisa M., Bosselut, Rémy
Publikováno v:
Science Immunology; 2022, Vol. 7 Issue 72, p1-18, 18p
Publikováno v:
Drug Week; 2/28/2023, p2572-2572, 1p