Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura Charlton"'
Autor:
Sara Medina-Lombardero, Connor Bain, Laura Charlton, Antonella Pellicoro, Holly Rocliffe, Jenna Cash, Robert Reuben, Michael L. Crichton
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100963- (2024)
Wounds are responsible for the decrease in quality of life of billions of people around the world. Their assessment relies on subjective parameters which often delays optimal treatments and results in increased healthcare costs. In this work, we soug
Externí odkaz:
https://doaj.org/article/f0a47e2f51c146e59b69dbf3d0fd8447
Autor:
David Novo, Nikki Heath, Louise Mitchell, Giuseppina Caligiuri, Amanda MacFarlane, Dide Reijmer, Laura Charlton, John Knight, Monika Calka, Ewan McGhee, Emmanuel Dornier, David Sumpton, Susan Mason, Arnaud Echard, Kerstin Klinkert, Judith Secklehner, Flore Kruiswijk, Karen Vousden, Iain R. Macpherson, Karen Blyth, Peter Bailey, Huabing Yin, Leo M. Carlin, Jennifer Morton, Sara Zanivan, Jim C. Norman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Some p53 mutants promote invasive migration of cancer cells and metastasis of tumours in vivo. However the key mechanistic details behind these phenomena remain unclear. Here the authors propose a non-cell autonomous mechanism involving fibroblasts,
Externí odkaz:
https://doaj.org/article/5887f05591104f9e9068f2413b7885fd
Autor:
James D. Glover, Zoe R. Sudderick, Barbara Bo-Ju Shih, Cameron Batho-Samblas, Laura Charlton, Andrew L. Krause, Calum Anderson, Jon Riddell, Adam Balic, Jinxi Li, Václav Klika, Thomas E. Woolley, Eamonn A. Gaffney, Andrea Corsinotti, Richard A. Anderson, Luke J. Johnston, Sara J. Brown, Sijia Wang, Yuhang Chen, Michael L. Crichton, Denis J. Headon
Publikováno v:
Cell, 2023, Vol.186(5), pp.940-956 [Peer Reviewed Journal]
Glover, J, Sudderick, Z, Shih, B, Batho-Samblas, C, Charlton, L, Krause, A L, Anderson, C, Riddell, J, Balic, A, Li, J, Klika, V, Woolley, T E, Gaffney, E A, Corsinotti, A, Anderson, R A, Johnston, L, Brown, S, Wang, S, Chen, Y, Crichton, M L & Headon, D 2023, ' The Developmental Basis of Fingerprint Pattern Formation and Variation ', Cell, vol. 186, pp. 1-17 . https://doi.org/10.1016/j.cell.2023.01.015
Glover, J, Sudderick, Z, Shih, B, Batho-Samblas, C, Charlton, L, Krause, A L, Anderson, C, Riddell, J, Balic, A, Li, J, Klika, V, Woolley, T E, Gaffney, E A, Corsinotti, A, Anderson, R A, Johnston, L, Brown, S, Wang, S, Chen, Y, Crichton, M L & Headon, D 2023, ' The Developmental Basis of Fingerprint Pattern Formation and Variation ', Cell, vol. 186, pp. 1-17 . https://doi.org/10.1016/j.cell.2023.01.015
Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint ridge formation and their intricate arrangements are unknown. Here we show that fingerprint ri
Membrane distillation is a thermally driven separation process using hydrophobic, porous membranes. Among various problems faced by membrane distillation, scaling remains an unresolved challenge in treating streams of high salinity. Development of su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028441792c4ffc8c63036f1bb838e54c
https://eprints.gla.ac.uk/263407/1/263407.pdf
https://eprints.gla.ac.uk/263407/1/263407.pdf
Autor:
Andrew Glidle, Matthew J. Dalby, Nan Qi, Phillip S. Dobson, Dan Wei, Hongsong Fan, Huabing Yin, Laura Charlton
Publikováno v:
ACS Applied Materials & Interfaces
It is well known that extracellular matrix stiffness can affect cell fate and change dynamically during many biological processes. Existing experimental means for in situ matrix stiffness modulation often alters its structure, which could induce addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a8d845b4be889ef9f14326cfa57e24
https://eprints.gla.ac.uk/247287/3/247287.pdf
https://eprints.gla.ac.uk/247287/3/247287.pdf
Autor:
Susan M. Mason, John R. P. Knight, Arnaud Echard, Giuseppina Caligiuri, Dide Reijmer, Monika Calka, Flore Kruiswijk, David Sumpton, David Novo, Karen Blyth, Iain R. Macpherson, Karen H. Vousden, Peter Bailey, Sara Zanivan, Kerstin Klinkert, Jim C. Norman, Judith Secklehner, Amanda MacFarlane, Nikki Heath, Huabing Yin, Jennifer P. Morton, Leo M. Carlin, Louise Mitchell, Ewan J. McGhee, Laura Charlton, Emmanuel Dornier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Nature Communications, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Novo, D, Heath, N, Mitchell, L, Caligiuri, G, MacFarlane, A, Reijmer, D, Charlton, L, Knight, J, Calka, M, McGhee, E, Dornier, E, Sumpton, D, Mason, S, Echard, A, Klinkert, K, Secklehner, J, Kruiswijk, F, Vousden, K, Macpherson, I R, Blyth, K, Bailey, P, Yin, H, Carlin, L M, Morton, J, Zanivan, S & Norman, J C 2018, ' Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels ', Nature Communications, vol. 9, no. 1, 5069 . https://doi.org/10.1038/s41467-018-07339-y
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Nature Communications, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Novo, D, Heath, N, Mitchell, L, Caligiuri, G, MacFarlane, A, Reijmer, D, Charlton, L, Knight, J, Calka, M, McGhee, E, Dornier, E, Sumpton, D, Mason, S, Echard, A, Klinkert, K, Secklehner, J, Kruiswijk, F, Vousden, K, Macpherson, I R, Blyth, K, Bailey, P, Yin, H, Carlin, L M, Morton, J, Zanivan, S & Norman, J C 2018, ' Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels ', Nature Communications, vol. 9, no. 1, 5069 . https://doi.org/10.1038/s41467-018-07339-y
Mutant p53s (mutp53) increase cancer invasiveness by upregulating Rab-coupling protein (RCP) and diacylglycerol kinase-α (DGKα)-dependent endosomal recycling. Here we report that mutp53-expressing tumour cells produce exosomes that mediate intercel
Autor:
Anne McAreavey, Laura Charlton
Publikováno v:
FPID Bulletin: The Bulletin of the Faculty for People with Intellectual Disabilities. 5:13-14