Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Laura Carroccia"'
Autor:
Lucio Pellacani, Stefania Fioravanti, Simona Gasbarri, Laura Carroccia, Fabio Sciubba, Emanuele Aresu
Publikováno v:
Tetrahedron. 69:9507-9511
Chiral racemic α-diimines, tested in aziridination reactions with NsONHCO2Et, for the first time led to the synthesis of (±)-bidiaziridines, stereoselectively derived from the corresponding meso (E-s-trans-E)-α-diimines. Moreover, a minor bidiazir
Publikováno v:
Journal of Flow Chemistry. 3:29-33
Microreactor-mediated organocatalysed Michael reactions have been developed. By using a soluble proline-derived catalyst, Michael-type reactions, leading to γ-nitroketones, have been optimized in homogeneous and continuous-flow conditions. As proof
Autor:
Giovanna Parisi, Marina Zenzola, Laura Carroccia, Luisa Pisano, Leonardo Degennaro, Flavio Fanelli, Giuseppe Romanazzi, Renzo Luisi
Publikováno v:
ChemInform. 47
Starting from readily available C2-substituted thietane 1-oxides, a straightforward synthesis of new C2,C4-disubstituted thietane 1-oxides has been developed by using a lithiation/electrophilic trapping sequence. The chemical and configurational stab
Publikováno v:
Tetrahedron. 67:5375-5381
(E)-Trifluoromethyl imines were considered as ideal substrates to be transformed into the corresponding diaziridines by a direct amination reaction with nosyloxycarbamates. The diastereoselective induction was strongly controlled by the N-substituent
Autor:
Giovanna Parisi, Laura Carroccia, Renzo Luisi, Leonardo Degennaro, Giuseppe Romanazzi, Flavio Fanelli, Marina Zenzola, Luisa Pisano
Publikováno v:
The Journal of organic chemistry. 80(24)
Starting from readily available C2-substituted thietane 1-oxides, a straightforward synthesis of new C2,C4-disubstituted thietane 1-oxides has been developed by using a lithiation/electrophilic trapping sequence. The chemical and configurational stab
Autor:
Giuseppe Romanazzi, Piero Mastrorilli, Piera Trinchera, Leonardo Degennaro, Luisa Pisano, Marina Zenzola, Rosanna Rizzi, Renzo Luisi, Arianna Giovine, Laura Carroccia
Publikováno v:
ChemInform. 46
This work demonstrates how the directing ability of the azetidine ring could be useful for regioselective ortho-CH functionalization of aryl compounds. Robust polar organometallic (lithiated) intermediates are involved in this synthetic strategy. The
Publikováno v:
Tetrahedron Letters. 54:4574-4576
New heterocyclic compounds characterized by the presence of a diaziridine and an oxaziridine ring directly bound were reported. A first desymmetrization reaction of α-diimines using nosyloxycarbamate as aminating agent in a H 2 O/CH 2 Cl 2 system gi
Autor:
Maria Laura Pati, Francesco Berardi, Carmen Abate, Laura Carroccia, Savina Ferorelli, Mauro Niso, Renzo Luisi, Marialessandra Contino
Publikováno v:
European journal of medicinal chemistry. 89
6,7-Dimethoxytetrahydroisoquinoline is widely used as basic moiety in σ2 receptor ligands, in order to provide σ2versus σ1 selectivity. This same moiety is also widely exploited in modulators of P-glycoprotein (P-gp) efflux pump, so that mixed σ2
Autor:
Arianna Giovine, Marina Zenzola, Aurelia Falcicchio, Renzo Luisi, Laura Carroccia, Piera Trinchera, Leonardo Degennaro, Giuseppe Romanazzi
Publikováno v:
ChemInform. 45
The regioselective lithiation–functionalization of 2-arylazetidines has been explored. The nature of the N-substituent is mainly responsible for a regioselectivity switch. ortho-Lithiation occurred, using hexyllithium as a greener base, in N-alkyla
Autor:
Simona Gasbarri, Fabio Sciubb, Stefania Fioravanti, Emanuele Aresu, Lucio Pellacani, Laura Carroccia
Publikováno v:
ChemInform. 45
The stereochemical outcome of the aziridination reaction of meso-α-diimines is investigated.