Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Laura C. Schulz"'
Autor:
Alexander P. Earhart, Natalia G. Karasseva, Kathryn M. Storey, Benjamin Olthoff, Md Bodruzzaman Sarker, Kimberly G. Laffey, Margaret J. Lange, R. Scott Rector, Laura C. Schulz, Diana Gil, Claudia M. Neuhauser, Adam G. Schrum
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113007- (2023)
Summary: Immune responses differ between females and males, although such sex-based variance is incompletely understood. Observing that bacteremia of the opportunistic pathogen Burkholderia gladioli caused many more deaths of female than male mice be
Externí odkaz:
https://doaj.org/article/1e4d898742b04a9995b7b49b3e3deaf5
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Concentrations of the hormone leptin, which is produced by adipose tissue, increase with increasing BMI, whereas leptin sensitivity often declines with higher BMI. Thus, altered leptin signaling may play a role in reproductive health risks o
Externí odkaz:
https://doaj.org/article/4d4af468a1e9440f838b9f11ddce7938
Autor:
Jie Zhou, Yuchen Tian, Ying Qu, Madyson Williams, Ye Yuan, Rowan M. Karvas, Megan A. Sheridan, Laura C. Schulz, Toshihiko Ezashi, Michael R. Roberts, Danny J. Schust
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The placenta acts as a protective barrier to pathogens and other harmful substances present in the maternal circulation throughout pregnancy. Disruption of placental development can lead to complications of pregnancy such as preeclampsia, intrauterin
Externí odkaz:
https://doaj.org/article/ef4317e854f24c9fbdf2b85ad558ca16
Publikováno v:
Metabolites, Vol 13, Iss 6, p 719 (2023)
Myostatin (gene symbol: Mstn) is an autocrine and paracrine inhibitor of muscle growth. Pregnant mice with genetically reduced levels of myostatin give birth to offspring with greater adult muscle mass and bone biomechanical strength. However, matern
Externí odkaz:
https://doaj.org/article/709a4f21c5ec41c19b456bd2781a8714
Autor:
Rebekah R. Starks, Rabab Abu Alhasan, Haninder Kaur, Kathleen A. Pennington, Laura C. Schulz, Geetu Tuteja
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8317 (2020)
During pregnancy, the placenta is important for transporting nutrients and waste between the maternal and fetal blood supply, secreting hormones, and serving as a protective barrier. To better understand placental development, we must understand how
Externí odkaz:
https://doaj.org/article/4a158dfc26fa4013b21540b4a2a17c59
Autor:
Kathleen A. Pennington, Jessica M. Schlitt, Daniel L. Jackson, Laura C. Schulz, Danny J. Schust
Publikováno v:
Disease Models & Mechanisms, Vol 5, Iss 1, Pp 9-18 (2012)
Preeclampsia is a pregnancy-specific disorder characterized by hypertension and excess protein excretion in the urine. It is an important cause of maternal and fetal morbidity and mortality worldwide. The disease is almost exclusive to humans and del
Externí odkaz:
https://doaj.org/article/ca09239970fe4f2ba145895fdd678559
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244971 (2021)
Maternal undernutrition has detrimental effects on fetal development and adult health. Total caloric restriction during early pregnancy followed by adequate nutrition for the remainder of gestation, is particularly linked to cardiovascular and metabo
Externí odkaz:
https://doaj.org/article/35035b12bd8a44cdae7b4031c6bf1631
Autor:
Toshihiko Ezashi, Laura C. Schulz, Jie Zhou, Teka Khan, Danny J. Schust, R. Michael Roberts, Jun Sugimoto
Publikováno v:
Placenta. 113:8-14
Three versions of syncytiotrophoblast exist in the human placenta: an invasive type associated with the implanting conceptus, non-invasive villous type of definitive placenta, and placental bed giant cells. Syncytins are encoded by modified env genes
Autor:
Adrienne Ohler, Tara K. Crawford, Victoria L Gremminger, Laura C. Schulz, R. Scott Rector, Emily N. Harrelson, Charlotte L. Phillips
Publikováno v:
Mol Genet Metab
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder with patients exhibiting bone fragility and muscle weakness. The synergistic biochemical and biomechanical relationship between bone and muscle is a critical potential therapeutic
Autor:
Jie Zhou, Megan A. Sheridan, Yuchen Tian, Kylie J. Dahlgren, Mark Messler, Ting Peng, Toshihiko Ezashi, Laura C. Schulz, Bret D. Ulery, R. Michael Roberts, Danny J. Schust
Publikováno v:
SSRN Electronic Journal.