High-Accuracy Relative Biological Effectiveness Values Following Low-Dose Thermal Neutron Exposures Support Bimodal Quality Factor Response with Neutron Energy

Autor: Laura C. Paterson, Amy Festarini, Marilyne Stuart, Fawaz Ali, Christie Costello, Chad Boyer, Ronald Rogge, Norma Ybarra, John Kildea, Richard B. Richardson

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 878
International Journal of Molecular Sciences, Vol 23, Iss 878, p 878 (2022)

Theoretical evaluations indicate the radiation weighting factor for thermal neutrons differs from the current International Commission on Radiological Protection (ICRP) recommended value of 2.5, which has radiation protection implications for high-en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e2cd7ba544cec8dc7dca97f4156a2a
http://europepmc.org/articles/PMC8779315

Total synthesis 2-epi-α-cedren-3-one via a cobalt-catalysed Pauson-Khand reaction

Autor: Mark McLaughlin, Laura C. Paterson, William J. Kerr, Colin M. Pearson

Publikováno v: Tetrahedron. 74:5062-5068

Herein we target the total synthesis of 2-epi-α-cedren-3-one, a natural compound isolated from the essential oil of Juniperus thurifera. Overall, our synthetic sequence presents an optimised and robust series of chemical transformations, with promin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc59252f95fb4f9f197ba4a88c65ea8
https://doi.org/10.1016/j.tet.2018.06.032

Low-dose radiobiology program at Canadian nuclear laboratories: past, present, and future

Autor: Farrah Flegal, Youssef Ismail, Richard B. Richardson, Heather Wyatt, Yi Wang, Dmitry Klokov, Soji Sebastian, Candice Didychuk, Laura A Bannister, Yevgeniya Le, Ali Fawaz, Laura C Paterson, Patrick Causey, Nicholas Priest

Publikováno v: International journal of radiation biology. 95(10)

Health risks associated with the exposure of humans to low-dose ionizing radiation are currently estimated using the Linear-No-Threshold model. Over the last few decades, however, this model has been widely criticized for inconsistency with a large b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e6d746c01892c4a5bed9b23e814c1a
https://pubmed.ncbi.nlm.nih.gov/30582711

Synthesis of the A–D Ring System of the Gambieric Acids

Autor: Alister Stewart, Laura C. Paterson, Lynne H. Thomas, Filippo Romiti, J. Stephen Clark, Subhabrata Chaudhury, Bora Sieng

Publikováno v: Organic Letters. 17:4694-4697

The A-D fragment of gambieric acids A and C has been synthesized using an asymmetric Tsuji-Trost allylation reaction to couple the two key segments. The A ring fragment has been prepared by a short and highly efficient route involving diastereoselect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba416d08a50e94d2e74ca73b5cfd5622
https://doi.org/10.1021/acs.orglett.5b02093

Z-Selective Dimerization of Aromatic Terminal Alkynes Catalyzed by an Iridium(I)-N-Heterocyclic Carbene-Phosphine System

Autor: Calum Forsyth, William J. Kerr, Laura C. Paterson

Publikováno v: Synlett. 24:587-590

The development of an iridium-catalyzed regio- and stereoselective dimerization process has enabled the formation of (Z)-enyne products. More specifically, low catalyst loadings of an iridium(I) complex, featuring a bulky N-heterocyclic carbene-phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a1b8ecac1a67b4e5125637d6d8d409
https://doi.org/10.1055/s-0032-1318271