Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura C. Mecker"'
Raman imaging of pharmaceutical materials: Refractive index effects on contrast at buried interfaces
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 105:17-23
Resolution targets composed of bilayer polydimethylsiloxane (PDMS) devices with buried polyethylene glycol (PEG) channels have been fabricated using traditional photolithographic and micromolding techniques to develop resolution targets that mimic ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab41815efb5e5bfcf1a732a18a4847a7
https://doi.org/10.1016/j.jpba.2014.11.033
https://doi.org/10.1016/j.jpba.2014.11.033
Publikováno v:
Analytical Chemistry. 83:3422-3430
In this work we describe a 96-well microplate assay for oversulfated chondroitin sulfate A (OSCS) in heparin, based on a water-soluble cationic polythiophene polymer (3-(2-(N-(N'-methylimidazole))ethoxy)-4-methylthiophene (LPTP)) and heparinase diges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31861ac27b18723e7bdb46724aa6d772
https://doi.org/10.1021/ac200011s
https://doi.org/10.1021/ac200011s
Autor:
R. Scott Martin, Laura C. Mecker
Publikováno v:
Analytical Chemistry. 80:9257-9264
Here we describe the fabrication, optimization, and application of a microfluidic device that integrates microdialysis (MD) sampling, microchip electrophoresis (ME), and electrochemical detection (EC). The manner in which the chip is produced is repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c851c907ac85061f1c52ab173e8b1c
https://doi.org/10.1021/ac801614r
https://doi.org/10.1021/ac801614r
Autor:
Laura C. Mecker, R. Scott Martin
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 12:296-302
In this article, we describe the fabrication and characterization of a reversibly sealed microchip device that is used to couple microdialysis sampling to microchip electrophoresis. The ability to interface microdialysis sampling and microchip electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e271368a01ac0156aa2e0e30ff1e110a
https://doi.org/10.1016/j.jala.2007.04.008
https://doi.org/10.1016/j.jala.2007.04.008
Autor:
Laura C. Mecker-Pogue, Jamie D. Dunn, Xia Ge, Daniel J. Mans, Ashley C. Gucinski, Jeff L.-F. Kao, Connie M. Gryniewicz-Ruzicka
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 83
A novel analogue of sibutramine, 11-desisobutyl-11-benzylsibutramine, has been discovered. During routine ion mobility spectrometry (IMS) screening of a weight loss supplement collected at an US FDA import operation facility an unknown peak was obser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59455f9ff8efb98eb102108f4df9b4dc
https://pubmed.ncbi.nlm.nih.gov/23739298
https://pubmed.ncbi.nlm.nih.gov/23739298
Autor:
Jamie D. Dunn, Daniel J. Mans, Lucinda F. Buhse, Laura C. Mecker-Pogue, Benjamin J. Westenberger, Connie M. Gryniewicz-Ruzicka, John F. Kauffman
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 71
Ion mobility spectrometry (IMS) served as a rapid, qualitative screening tool for the analysis of adulterated weight-loss products. We have previously shown that sibutramine extracted into methanol from dietary supplements can be detected at low leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a315ed87150003e7e2970ca97407023d
https://pubmed.ncbi.nlm.nih.gov/22902504
https://pubmed.ncbi.nlm.nih.gov/22902504
Autor:
Connie M. Gryniewicz-Ruzicka, Katherine M. Tyner, John F. Kauffman, Daniel J. Mans, Laura C. Mecker, Sergey Arzhantsev
Publikováno v:
Analytica chimica acta. 733
Melamine adulteration of food and pharmaceutical products is a major concern and there is a growing need to protect the public from exposure to contaminated or adulterated products. One approach to reduce this threat is to develop a portable method f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1dc504bf1637672f9551a2ed667de1
https://pubmed.ncbi.nlm.nih.gov/22704375
https://pubmed.ncbi.nlm.nih.gov/22704375
In this communication, we demonstrate that a carbon ink microelectrode array, where the electrodes are held at the same potential, affords significant signal enhancement in microchip electrophoresis with amperometric detection. The ability to fabrica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984fd114a7c997f1832125aa59001cda
https://europepmc.org/articles/PMC3092702/
https://europepmc.org/articles/PMC3092702/
Autor:
Laura C. Mecker, R. Scott Martin
Publikováno v:
Electrophoresis. 27(24)
The fabrication and evaluation of micromolded dual carbon ink electrodes and their integration with a fabricated palladium decoupler for use in microchip electrophoresis is described. As opposed to previous work involving carbon-based dual electrodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69710058002e70bc82b1979d4c0a790
https://pubmed.ncbi.nlm.nih.gov/17096314
https://pubmed.ncbi.nlm.nih.gov/17096314
Autor:
Laura C. Mecker, R. Scott Martin
Publikováno v:
ECS Meeting Abstracts. :1454-1454
not Available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83ff2b35106f0aabfcc859624dca6284
https://doi.org/10.1149/ma2007-02/31/1454
https://doi.org/10.1149/ma2007-02/31/1454