Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laura C. Jacques"'
Autor:
Laura C. Jacques, Angharad E. Green, Thomas E. Barton, Murielle Baltazar, Julia Aleksandrowicz, Rong Xu, Erwan Trochu, Aras Kadioglu, Daniel R. Neill
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The short generation time of many bacterial pathogens allows the accumulation of de novo mutations during routine culture procedures used for the preparation and propagation of bacterial stocks. Taking the major human pathogen Streptococcus
Externí odkaz:
https://doaj.org/article/de92f347b347461c935269ceef1608a9
Autor:
Rong Xu, Laura C. Jacques, Shadia Khandaker, Daan Beentjes, Miguel Leon-Rios, Xiaoqing Wei, Neil French, Daniel R. Neill, Aras Kadioglu
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112054- (2023)
Summary: Streptococcus pneumoniae is a pathogen of global morbidity and mortality. Pneumococcal pneumonia can lead to systemic infections associated with high rates of mortality. We find that, upon pneumococcal infection, pulmonary Treg cells are act
Externí odkaz:
https://doaj.org/article/5bd0903ad9fd4e9e86620d19bbfddae3
Autor:
Laura C. Jacques, Stavros Panagiotou, Murielle Baltazar, Madikay Senghore, Shadia Khandaker, Rong Xu, Laura Bricio-Moreno, Marie Yang, Christopher G. Dowson, Dean B. Everett, Daniel R. Neill, Aras Kadioglu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The mechanisms behind the high invasiveness of Streptococcus pneumoniae serotype 1 are unclear. Here, Jacques et al. show that this feature is due to overproduction and rapid release of pneumolysin, which induces cytotoxicity and breakdown of tight j
Externí odkaz:
https://doaj.org/article/4e3fa97f73434e33a5cdb4df33c7b5d6
Autor:
Gabrielle Stack, Emma Jones, Morgan Marsden, Maria A Stacey, Robert J Snelgrove, Paul Lacaze, Laura C Jacques, Simone M Cuff, Richard J Stanton, Awen M Gallimore, Tracy Hussell, Gavin W G Wilkinson, Peter Ghazal, Philip R Taylor, Ian R Humphreys
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004641 (2015)
CD200 receptor (CD200R) negatively regulates peripheral and mucosal innate immune responses. Viruses, including herpesviruses, have acquired functional CD200 orthologs, implying that viral exploitation of this pathway is evolutionary advantageous. Ho
Externí odkaz:
https://doaj.org/article/e69f5ed2db144e32af2dee37e2b1a0ca
Publikováno v:
Trends in microbiology. 30(6)
Streptococcus pneumoniae (the 'pneumococcus') is a significant cause of morbidity and mortality worldwide, causing life-threatening diseases such as pneumonia, bacteraemia, and meningitis, with an annual death burden of over one million. Discovered o
Autor:
Waleed H. Mahallawi, Laura C. Jacques, Paul S. McNamara, Katja Hoschler, Helen Beer, Nav Upile, Francesca Ferrara, Nigel J. Temperton, Ravi Sharma, Qibo Zhang, Muhammad S Ahmed, Casey Vaughan
Publikováno v:
ANTIVIRAL RESEARCH
2009 H1N1 pandemic influenza (A(H1N1)pdm09) virus infected large numbers of people worldwide. Recent studies suggest infection with A(H1N1)pdm09 virus elicited cross-reactive anti-hemagglutinin (HA) memory B cell response to conserved regions of HA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10965bd6f775d50cd1f40f6bb26b7ca7