Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura C. D. Pomatto"'
Autor:
Alberto Diaz-Ruiz, Tyler Rhinesmith, Laura C. D. Pomatto-Watson, Nathan L. Price, Farzin Eshaghi, Margaux R. Ehrlich, Jacqueline M. Moats, Melissa Carpenter, Annamaria Rudderow, Sebastian Brandhorst, Julie A. Mattison, Miguel A. Aon, Michel Bernier, Valter D. Longo, Rafael de Cabo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Understanding the contribution of diet composition, calories and length of fasting in health maintenance is still challenging. Here the authors compare the effects of cycles of intermittent very low calorie intake achieved with a plant-based fasting
Externí odkaz:
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
Autor:
Laura C. D. Pomatto-Watson, Monica Bodogai, Oye Bosompra, Jonathan Kato, Sarah Wong, Melissa Carpenter, Eleonora Duregon, Dolly Chowdhury, Priya Krishna, Sandy Ng, Emeline Ragonnaud, Roberto Salgado, Paula Gonzalez Ericsson, Alberto Diaz-Ruiz, Michel Bernier, Nathan L. Price, Arya Biragyn, Valter D. Longo, Rafael de Cabo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Caloric restriction (CR) has been shown as an effective intervention to reduce tumorigenesis, but alternative less stringent dietary interventions have also been considered. Here, the authors show that in a murine model of breast cancer CR has a larg
Externí odkaz:
https://doaj.org/article/23bdba50f5d9416ba338e8343d216d8e
Autor:
Laura C. D. Pomatto-Watson, Monica Bodogai, Melissa Carpenter, Dolly Chowdhury, Priya Krishna, Sandy Ng, Oye Bosompra, Jonathan Kato, Sarah Wong, Carlos Reyes-Sepulveda, Michel Bernier, Nathan L. Price, Arya Biragyn, Rafael de Cabo
Publikováno v:
GeroScience
Caloric restriction (CR) is the leading non-pharmacological intervention to delay induced and spontaneous tumors in pre-clinical models. These effects of CR are largely attributed to canonical inhibition of pro-growth pathways. However, our recent da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3835d66f280c13f919567fb1fcd3f976
https://doi.org/10.1007/s11357-022-00635-y
https://doi.org/10.1007/s11357-022-00635-y
Autor:
Farzin Eshaghi, Sebastian Brandhorst, Tyler Rhinesmith, Jacqueline M. Moats, Laura C. D. Pomatto-Watson, Alberto Diaz-Ruiz, Julie A. Mattison, Miguel A. Aon, Nathan L. Price, Annamaria L Rudderow, Melissa Carpenter, Valter D. Longo, Margaux R. Ehrlich, Rafael de Cabo, Michel Bernier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Diet composition, calories, and fasting times contribute to the maintenance of health. However, the impact of very low-calorie intake (VLCI) achieved with either standard laboratory chow (SD) or a plant-based fasting mimicking diet (FMD) is not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb9b9f429efca44c8c5b24289160c0e
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
Autor:
Sheldon Rowan, Shuhong Jiang, Sarah G. Francisco, Laura C. D. Pomatto, Zhiwei Ma, Xiaodong Jiao, Maria M. Campos, Sandeep Aryal, Shaili D. Patel, Binapani Mahaling, S. Amer Riazuddin, Elia J. Duh, Salil A. Lachke, J. Fielding Hejtmancik, Rafael de Cabo, Paul G. FitzGerald, Allen Taylor
Publikováno v:
Investigative ophthalmology & visual science, vol 62, iss 15
Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science
Purpose Age-related cataracts affect the majority of older adults and are a leading cause of blindness worldwide. Treatments that delay cataract onset or severity have the potential to delay cataract surgery, but require relevant animal models that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfc6180f7e42f5e7785cd513a215d47
https://escholarship.org/uc/item/3d327405
https://escholarship.org/uc/item/3d327405
Autor:
Rafael de Cabo, Nathan L. Price, Michel Bernier, Eleonora Duregon, Laura C. D. Pomatto-Watson
Publikováno v:
GeroScience. 43(3)
The global human population has recently experienced an increase in life expectancy with a mounting concern about the steady rise in the incidence of age-associated chronic diseases and socio-economic burden. Calorie restriction (CR), the reduction o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b5c6e81e1897ef4774a874b36b1624
https://pubmed.ncbi.nlm.nih.gov/33686571
https://pubmed.ncbi.nlm.nih.gov/33686571
Autor:
Alberto Diaz-Ruiz, Dolly Chowdhury, Eleonora Duregon, Oye Bosompra, Nathan L. Price, Paula Gonzalez Ericsson, Rafael de Cabo, Jonathan Kato, Arya Biragyn, Sandy Ng, Melissa Carpenter, Roberto Salgado, Michel Bernier, Monica Bodogai, Emeline Ragonnaud, Valter D. Longo, Sarah Wong, Laura C. D. Pomatto-Watson, Priya Krishna
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Cancer incidence increases with age and is a leading cause of death. Caloric restriction (CR) confers benefits on health and survival and delays cancer. However, due to CR’s stringency, dietary alternatives offering the same cancer protection have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0d39683d0eee7a603b4b8a10e6bc80
https://pubmed.ncbi.nlm.nih.gov/34707136
https://pubmed.ncbi.nlm.nih.gov/34707136
Publikováno v:
Data in Brief
Adaptive homeostasis enables rapid cellular signaling, leading to transcriptional and translational modifications (Davies, 2016) [1]. The Proteasome is one of the main cellular proteolytic enzymes that plays an essential role in the rapid clearance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2856ffd772efe8823b00d19c89a2e420
https://pubmed.ncbi.nlm.nih.gov/29552615
https://pubmed.ncbi.nlm.nih.gov/29552615
Publikováno v:
Biological reviews of the Cambridge Philosophical Society. 92(2)
Peroxisomes are ubiquitous eukaryotic organelles with the primary role of breaking down very long- and branched-chain fatty acids for subsequent β-oxidation in the mitochondrion. Like mitochondria, peroxisomes are major sites for oxygen utilization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::175834980c580fdeaf1bd5ecdb032870
https://pubmed.ncbi.nlm.nih.gov/26852705
https://pubmed.ncbi.nlm.nih.gov/26852705