Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Laura C Torchen"'
Autor:
Elizabeth Roof, Cheri L Deal, Shawn E McCandless, Ronald L Cowan, Jennifer L Miller, Jill K Hamilton, Elizabeth R Roeder, Shana E McCormack, Tamanna R Roshan Lal, Hussein D Abdul-Latif, Andrea M Haqq, Kathryn S Obrynba, Laura C Torchen, Alaina P Vidmar, David H Viskochil, Jean-Pierre Chanoine, Carol K L Lam, Melinda J Pierce, Laurel L Williams, Lynne M Bird, Merlin G Butler, Diane E Jensen, Susan E Myers, Oliver J Oatman, Charumathi Baskaran, Laura J Chalmers, Cary Fu, Nathalie Alos, Scott D McLean, Ajay Shah, Barbara Y Whitman, Brent A Blumenstein, Sarah F Leonard, Jessica P Ernest, Joseph W Cormier, Sara P Cotter, Davis C Ryman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by endocrine and neuropsychiatric problems including hyperphagia, anxiousness, and distress. Intranasal carbetocin, an oxytocin analog, was investigated as a selective oxyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40931114e5833e6e552c8b0c9d0399d7
https://doi.org/10.1210/clinem/dgad015
https://doi.org/10.1210/clinem/dgad015
Autor:
Laura C Torchen, Apoorva Aekka, Sarayu Ratnam, Kelly Brewer, Sabah Islam, Chun Li, Andrea Dunaif
Publikováno v:
Journal of the Endocrine Society. 6:A650-A651
Physiologic and genetic analyses implicate hyperandrogenemia (HA) as a core causal pathway in PCOS. Both daughters of women with PCOS (PCOS-d) and overweight/obese girls (OW-g) have HA beginning in childhood suggesting that they are at increased risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eeaf67117046e167bf00c3d33d2e8e9
https://doi.org/10.1210/jendso/bvac150.1345
https://doi.org/10.1210/jendso/bvac150.1345
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 104:3355-3361
CONTEXT: Increased testosterone (T) levels are a cardinal feature of polycystic ovary syndrome (PCOS). Female relatives of affected women, including premenarchal daughters, have elevated T levels supporting a genetic susceptibility to this phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f0d66347ff733d950945e9e8414d16
https://doi.org/10.1210/jc.2018-02313
https://doi.org/10.1210/jc.2018-02313
Autor:
Laura C. Torchen, Richard J. Auchus, Adina F. Turcu, Andrea Dunaif, Ryan Sisk, Richard S. Legro
Publikováno v:
J Clin Endocrinol Metab
Context Hyperandrogenemia (HA) is a consistent reproductive phenotype in women with polycystic ovary syndrome (PCOS) and their relatives. Increased testosterone levels are present in premenarchal daughters of affected women (PCOS-d). Obese girls (OB-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac237e712376e2d6c7afa9e030a5ee5
https://europepmc.org/articles/PMC7500474/
https://europepmc.org/articles/PMC7500474/
Publikováno v:
Journal of the Endocrine Society
Background: Congenital leptin deficiency (CLD) is a rare autosomal recessive form of monogenic obesity caused by loss-of-function mutations in the leptin gene. Targeted therapy is available in the form of recombinant human leptin (metreleptin). Previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b555e4fcacbbd47e179d8241a1102c
http://europepmc.org/articles/PMC7207930
http://europepmc.org/articles/PMC7207930
Autor:
Geralyn Lambert-Messerlian, Bhanu Kalra, Gopal Savjani, Laura C. Torchen, Anthony Morrison, Tanya Kumar, Amita Patel, Ajay Kumar, Glenn E. Palomaki, Andrea Dunaif
Publikováno v:
Fertil Steril
Objective To examine whether accounting for a woman’s age and body mass index (BMI) would improve the ability of antimullerian hormone (AMH) to distinguish between women with (cases) and without (controls) polycystic ovarian syndrome (PCOS). Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b15f10cb4b6245f0f3d141b8f307f4f
https://europepmc.org/articles/PMC7583345/
https://europepmc.org/articles/PMC7583345/
Autor:
Marcelle I. Cedars, James G. Terry, Veeral Ajmera, Lisa B. VanWagner, Monika Sarkar, Norah A. Terrault, David S. Siscovick, J. Jeffrey Carr, Erica P. Gunderson, Laura C. Torchen, Cora E. Lewis, Mary E. Rinella, Melissa Wellons
Publikováno v:
American Journal of Gastroenterology. 112:755-762
Young women with hyperandrogenism have high risk of metabolic co-morbidities, including increased risk of nonalcoholic fatty liver disease (NAFLD). Whether testosterone (the predominant androgen) is associated with NAFLD independent of metabolic co-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb86b9b1b80a55e9b7bab7ff959364e
https://doi.org/10.1038/ajg.2017.44
https://doi.org/10.1038/ajg.2017.44
Publikováno v:
Journal of the Endocrine Society
Both daughters of women with PCOS (PCOS-d) and overweight girls (OW-g) are proposed to be at increased risk of PCOS because they have peripubertal increases in testosterone (T) levels, a cardinal feature of PCOS. We are testing this hypothesis by per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd8908fa8c27937230b1f8a7da8c995
https://doi.org/10.1210/jendso/bvab048.1503
https://doi.org/10.1210/jendso/bvab048.1503
Autor:
Bhanu Kalra, Ryan Sisk, Gopal Savjani, Laura C. Torchen, Ashok Kumar, Andrea Dunaif, Richard S. Legro
Publikováno v:
Fertility and Sterility. 106:50-55
Objective To investigate for differences in reproductive hormone levels in male relatives of women with polycystic ovary syndrome (PCOS). Design Cross-sectional study. Setting Academic medical center. Patient(s) Sixty-three fathers and 66 brothers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01ff3fa4a80d29bf05b663e5233e453
https://doi.org/10.1016/j.fertnstert.2016.03.029
https://doi.org/10.1016/j.fertnstert.2016.03.029
Autor:
Laura C. Torchen, Prathima Jasti, Matthew Dapas, Margrit Urbanek, Rodrigo Macaya, Andrea Dunaif, M. Geoffrey Hayes, Joy N. Tsai, Ryan Sisk
Publikováno v:
Obesity (Silver Spring)
OBJECTIVE Women with metabolic syndrome (MetS) have higher endogenous testosterone (T) levels than unaffected women. This study investigated whether hyperandrogenemia (HA) was a marker for increased cardiometabolic risk in reproductively normal preme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7199bb214e637733c519a36e13f7cf
https://pubmed.ncbi.nlm.nih.gov/31729166
https://pubmed.ncbi.nlm.nih.gov/31729166