Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Laura C Pollitt"'
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005003 (2015)
Very little is known about how vector-borne pathogens interact within their vector and how this impacts transmission. Here we show that mosquitoes can accumulate mixed strain malaria infections after feeding on multiple hosts. We found that parasites
Externí odkaz:
https://doaj.org/article/1f5a90ef3b0542368b6ba2ae9d4f6dd0
Autor:
Laura C Pollitt, Silvie Huijben, Derek G Sim, Rahel M Salathé, Matthew J Jones, Andrew F Read
Publikováno v:
PLoS Pathogens, Vol 10, Iss 4, p e1004019 (2014)
The evolution of drug resistance, a key challenge for our ability to treat and control infections, depends on two processes: de-novo resistance mutations, and the selection for and spread of resistant mutants within a population. Understanding the fa
Externí odkaz:
https://doaj.org/article/67bf92882bc64db4bb489730da5801c1
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002590 (2012)
Explaining the contribution of host and pathogen factors in driving infection dynamics is a major ambition in parasitology. There is increasing recognition that analyses based on single summary measures of an infection (e.g., peak parasitaemia) do no
Externí odkaz:
https://doaj.org/article/26cc2fa6e99e48d78a8d5dfc336379b7
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002320 (2011)
The discovery that an apoptosis-like, programmed cell death (PCD) occurs in a broad range of protozoan parasites offers novel therapeutic tools to treat some of the most serious infectious diseases of humans, companion animals, wildlife, and livestoc
Externí odkaz:
https://doaj.org/article/baa0f3c1d5554485843842682f713918
Publikováno v:
Evolutionary Applications
Artemisinin-based drugs are the front-line weapon in the treatment of human malaria cases, but there is concern that recent reports of slow clearing infections may signal developing resistance to treatment. In the absence of molecular markers for res
Autor:
Nicole Mideo, Lucy M. Carter, Manuel Llinás, Sarah E. Reece, Laura C. Pollitt, Björn F.C. Kafsack
Publikováno v:
Evolution, Medicine, and Public Health
For vector-borne parasites such as malaria, how within- and between-host processes interact to shape transmission is poorly understood. In the host, malaria parasites replicate asexually but for transmission to occur, specialized sexual stages (gamet
Publikováno v:
Malaria Journal
BACKGROUND: A series of elegant experiments was recently published which demonstrated that transmission of malaria parasites through mosquitoes elicited an attenuated growth phenotype, whereby infections grew more slowly and reached peak parasitaemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89af4271b68e8485f20ac7943b0150c
https://ora.ox.ac.uk/objects/uuid:a2510190-9b86-4b60-8d86-d6bf8fde6397
https://ora.ox.ac.uk/objects/uuid:a2510190-9b86-4b60-8d86-d6bf8fde6397
Publikováno v:
Reece, S E, Pollitt, L C, Colegrave, N & Gardner, A 2011, ' The Meaning of Death: Evolution and Ecology of Apoptosis in Protozoan Parasites ', PLoS Pathogens, vol. 7, no. 12, e1002320, pp.-. https://doi.org/10.1371/journal.ppat.1002320
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 12, p e1002320 (2011)
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 12, p e1002320 (2011)
The discovery that an apoptosis-like, programmed cell death (PCD) occurs in a broad range of protozoan parasites offers novel therapeutic tools to treat some of the most serious infectious diseases of humans, companion animals, wildlife, and livestoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1838d1ebcb2e76d3b3dc8fcf9de3fafd
https://ora.ox.ac.uk/objects/uuid:c3c4d901-f4b4-4014-89f6-beb652968fbd
https://ora.ox.ac.uk/objects/uuid:c3c4d901-f4b4-4014-89f6-beb652968fbd
Publikováno v:
Trends in Parasitology
Pollitt, L C, MacGregor, P, Matthews, K & Reece, S E 2011, ' Malaria and trypanosome transmission: different parasites, same rules? ', Trends in Parasitology, vol. 27, no. 5, pp. 197-203 . https://doi.org/10.1016/j.pt.2011.01.004
Pollitt, L C, MacGregor, P, Matthews, K & Reece, S E 2011, ' Malaria and trypanosome transmission: different parasites, same rules? ', Trends in Parasitology, vol. 27, no. 5, pp. 197-203 . https://doi.org/10.1016/j.pt.2011.01.004
African trypanosomes produce different specialized stages for within-host replication and between-host transmission and therefore face a resource allocation trade-off between maintaining the current infection (survival) and investment into transmissi
Autor:
Laura C. Pollitt, David M. Shuker, Tom J. Little, Stuart K. J. R. Auld, Alastair J. Wilson, Andrea L. Graham
Publikováno v:
Functional Ecology. 25:5-17
Summary 1. Ecoimmunologists aim to understand the costs, benefits, and net fitness consequences of different strategies for immune defense. 2. Measuring the fitness consequences of immune responses is difficult, partly because of complex relationship