Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Laura C Alonso"'
Autor:
Joshua JN Burton, Laura C Alonso
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 3, Pp 263-274 (2024)
Abstract Overconsumption of energy‐rich foods that disrupt caloric balance is a fundamental cause of overweight, obesity and diabetes. Dysglycemia and the resulting cardiovascular disease cause substantial morbidity and mortality worldwide, as well
Externí odkaz:
https://doaj.org/article/f900eb573b1c4fb2b86cb30f52fadc61
Autor:
Benjamin Udoka Nwosu, Bo Zhang, Sanaa S Ayyoub, Stephanie Choi, Tony R Villalobos-Ortiz, Laura C Alonso, Bruce A Barton
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196912 (2018)
Landmark studies showed that partial clinical remission in new-onset type 1 diabetes is associated with reduced prevalence of long-term complications, but early clinical indicators of this favorable outcome are poorly characterized.To determine if th
Externí odkaz:
https://doaj.org/article/c4c0cd680f154e03b3b11973950f711f
Autor:
Katherine R Marino, Rachel L Lundberg, Aastha Jasrotia, Louise S Maranda, Michael J Thompson, Bruce A Barton, Laura C Alonso, Benjamin Udoka Nwosu
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176860 (2017)
>50% of patients with new-onset type 1 diabetes (T1D) do not enter partial clinical remission (PCR); early identification of these patients may improve initial glycemic control and reduce long-term complications.To determine whether routinely obtaina
Externí odkaz:
https://doaj.org/article/d102900782544669bc8b14f041388ab5
Autor:
Gamze Kilic, Ana I Alvarez-Mercado, Bader Zarrouki, Darren Opland, Chong Wee Liew, Laura C Alonso, Martin G Myers, Jean-Christophe Jonas, Vincent Poitout, Rohit N Kulkarni, Franck Mauvais-Jarvis
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87941 (2014)
The female steroid, 17β-estradiol (E2), is important for pancreatic β-cell function and acts via at least three estrogen receptors (ER), ERα, ERβ, and the G-protein coupled ER (GPER). Using a pancreas-specific ERα knockout mouse generated using
Externí odkaz:
https://doaj.org/article/ed2b0ea788fa41138aad1bca00fcc666
Autor:
Yoshio Watanabe, Srikanth Singamsetty, Baobo Zou, Lanping Guo, Darko Stefanovski, Laura C Alonso, Adolfo Garcia-Ocana, Christopher P O'Donnell, Bryan J McVerry
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67716 (2013)
OBJECTIVES:The development of hyperglycemia and the use of early parenteral feeding are associated with poor outcomes in critically ill patients. We therefore examined the impact of exogenous glucose administration on the integrated metabolic functio
Externí odkaz:
https://doaj.org/article/6921dadee4f546eb8cb48fa84fa4d68c
Autor:
Søs Skovsø, Evgeniy Panzhinskiy, Jelena Kolic, Haoning Howard Cen, Derek A. Dionne, Xiao-Qing Dai, Rohit B. Sharma, Lynda Elghazi, Cara E. Ellis, Katharine Faulkner, Stephanie A. M. Marcil, Peter Overby, Nilou Noursadeghi, Daria Hutchinson, Xiaoke Hu, Hong Li, Honey Modi, Jennifer S. Wildi, J. Diego Botezelli, Hye Lim Noh, Sujin Suk, Brian Gablaski, Austin Bautista, Ryekjang Kim, Corentin Cras-Méneur, Stephane Flibotte, Sunita Sinha, Dan S. Luciani, Corey Nislow, Elizabeth J. Rideout, Eric N. Cytrynbaum, Jason K. Kim, Ernesto Bernal-Mizrachi, Laura C. Alonso, Patrick E. MacDonald, James D. Johnson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Insulin receptor protein is present in pancreatic β-cells, but the consequences of β-cell insulin resistance are incompletely understood. Here the authors use a combination of mouse studies and mathematical modelling to show that loss of beta-cell
Externí odkaz:
https://doaj.org/article/34fcff15f65143fa8ca0bab84b4cd93e
Autor:
Beverly G. Tchang, Chenel Morrison, Joon Tae Kim, Farheen Ahmed, Karina M. Chan, Laura C. Alonso, Louis J. Aronne, Alpana P. Shukla
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundAmidst the COVID-19 pandemic, telemedicine was rapidly implemented to maintain patient care during quarantine. However, there is little data on how this transition may have impacted weight loss outcomes and interventions among patients with
Externí odkaz:
https://doaj.org/article/396b9117708b47e89378327327a31356
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Aging is associated with loss of proliferation of the insulin-secreting β-cell, a possible contributing factor to the increased prevalence of type 2 diabetes in the elderly. Our group previously discovered that moderate endoplasmic reticulum (ER) st
Externí odkaz:
https://doaj.org/article/728bcb8b23a14288b1c2f25dfae7ce74
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
The CDKN2A/B genomic locus is associated with risk of human cancers and metabolic disease. Although the locus contains several important protein-coding genes, studies suggest disease roles for a lesser-known antisense lncRNA encoded at this locus, ca
Externí odkaz:
https://doaj.org/article/ec4f9964861343a5a1fe68db7950e262
Publikováno v:
Diabetes
Type 2 diabetes (T2D) is a growing cause of poor health, psychosocial burden, and economic costs worldwide. The pancreatic β-cell is a cornerstone of metabolic physiology. Insulin deficiency leads to hyperglycemia, which was fatal before the availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d107430e83123182f15d547a09b19d17
https://doi.org/10.2337/dbi20-0033
https://doi.org/10.2337/dbi20-0033