Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Laura C, Tumiati"'
Autor:
Andrzej Chruscinski, Flora Y Y Huang, Albert Nguyen, Jocelyn Lioe, Laura C Tumiati, Stella Kozuszko, Kathryn J Tinckam, Vivek Rao, Shannon E Dunn, Michael A Persinger, Gary A Levy, Heather J Ross
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151224 (2016)
Autoantibodies directed against endogenous proteins including contractile proteins and endothelial antigens are frequently detected in patients with heart failure and after heart transplantation. There is evidence that these autoantibodies contribute
Externí odkaz:
https://doaj.org/article/f18ac9741fee4286b055c3a42b9a15a3
Autor:
Laura C. Tumiati, Andrzej Chruscinski, Vivek Rao, Prabjit Ajrawat, Filio Billia, Liza Grosman-Rimon, Jocelyn Lioe
Publikováno v:
Journal of Cardiac Failure. 25:301-306
Left ventricular assist devices (LVADs) can serve as a bridge to transplant or destination therapy for patients with advanced heart failure. Implantation of LVADs is known to be associated with increases in anti-HLA antibodies, but less is known abou
Autor:
Ren-Ke Li, Jagdish Butany, Maral Ouzounian, Terrence M. Yau, Songbin Fu, Jian Guo, Tirone E. David, Hui-Fang Song, Laura C. Tumiati, Jie Wu, Katherine Tsang, Shu-Hong Li, Richard D. Weisel
Publikováno v:
Journal of the American College of Cardiology. 67:2965-2977
Background Patients with a bicuspid aortic valve (BAV) are at increased risk for progressive aortic dilation associated with extracellular matrix (ECM) degradation by matrix metalloproteinases (MMP). However, the mechanisms responsible for initiating
Autor:
Azadeh Yeganeh, Tirone E. David, Myunghyun M. Lee, Katherine Tsang, Maral Ouzounian, Shu-Hong Li, Laura C. Tumiati, Terrence M. Yau, Faisal J. Alibhai, Jagdish Butany, Jian Guo, Richard D. Weisel, Stephanie W. Tobin, Jie Wu, Rodolfo V. Rocha, Ren-Ke Li
Publikováno v:
Journal of molecular and cellular cardiology. 132
Bicuspid aortic valve (BAV) disease is a congenital abnormality that is associated with ascending aortic aneurysm yet many of the molecular mechanisms remain unknown. To identify novel molecular mechanisms of aneurysm formation we completed microarra
Autor:
Laura C. Tumiati, Heather J. Ross, Mitchell B. Adamson, A.G. Mociornita, Vivek Rao, Diego H. Delgado
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18(12)
Human leukocyte antigen-G (HLA-G) expression is modulated by immunosuppressant use and is associated with lower incidence of graft rejection and cardiac allograft vasculopathy (CAV). We examined whether everolimus induces HLA-G expression and inhibit
Autor:
Julieta Lazarte, Arash Ghashghai, Laura C. Tumiati, Stacey Pollock Bar-Ziv, Michael McDonald, Hiroyuki Kawajiri, Vivek Rao, Liza Grosman-Rimon, Ira Jacobs, Avi Fuks, Daniel J. Shogilev, David Z.I. Cherney
Publikováno v:
Canadian Journal of Cardiology. 31:348-356
Background The long-term effects of continuous-flow left ventricular assist device (CF-LVAD) support on trends of inflammatory markers over time are unknown. We examined the hypothesis that the levels of inflammatory markers in CF-LVAD recipients are
Publikováno v:
Human immunology. 79(8)
The Human Leukocyte Antigen-G (HLA-G) is a MHC-class Ib molecule with robust immunomodulatory properties; in transplant, it inhibits cytotoxic activity of immune cells and thus has a pivotal role in protecting the allograft from immune attack. The pr
Autor:
A.G. Mociornita, Arash Ghashghai, Vivek Rao, Daniel J. Shogilev, Ira Jacobs, Andrzej Chruscinski, Liza Grosman-Rimon, David Z.I. Cherney, Laura C. Tumiati, Michael McDonald, Stacey Pollock Bar-Ziv
Publikováno v:
ASAIO Journal. 60:657-663
Although the newer continuous-flow left ventricular assist devices (CF-LVADs) provide clinical advantages over the pulsatile pumps, the effects of low pulsatility on inflammation are incompletely understood. The objective of our study was to examine
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 157:615-625.e1
Hypertonic saline (HTS) has potent immune and vascular effects. We assessed recipient pretreatment with HTS on allograft function in a porcine model of heart transplantation and hypothesized that HTS infusion would limit endothelial and left ventricu
Autor:
Laura C. Tumiati, Heather J. Ross, Diego H. Delgado, Chethan J. Sathya, Jessica L. Prodger, Vivek Rao, Rohit Sheshgiri
Publikováno v:
Transplant International. 23:641-648
Endothelial progenitor cells (EPCs) may contribute to rejection and cardiac allograft vasculopathy (CAV) by being intrinsically involved in the rejection process and causing neointimal hyperplasia. The mammalian target of rapamycin inhibitors (mTORi)