Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Laura Buggiotti"'
Autor:
Joseph F. Standing, Laura Buggiotti, Jose Afonso Guerra-Assuncao, Maximillian Woodall, Samuel Ellis, Akosua A. Agyeman, Charles Miller, Mercy Okechukwu, Emily Kirkpatrick, Amy I. Jacobs, Charlotte A. Williams, Sunando Roy, Luz M. Martin-Bernal, Rachel Williams, Claire M. Smith, Theo Sanderson, Fiona B. Ashford, Beena Emmanuel, Zaheer M. Afzal, Adrian Shields, Alex G. Richter, Jienchi Dorward, Oghenekome Gbinigie, Oliver Van Hecke, Mark Lown, Nick Francis, Bhautesh Jani, Duncan B. Richards, Najib M. Rahman, Ly-Mee Yu, Nicholas P. B. Thomas, Nigel D. Hart, Philip Evans, Monique Andersson, Gail Hayward, Kerenza Hood, Jonathan S. Nguyen-Van-Tam, Paul Little, F. D. Richard Hobbs, Saye Khoo, Christopher Butler, David M. Lowe, Judith Breuer, PANORAMIC Virology Group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 symptoms randomised to receive molnupiravir (n = 253) or Us
Externí odkaz:
https://doaj.org/article/01afce3eddb24d8aa3b7e67fa19987db
Autor:
Laura Buggiotti, Zhangrui Cheng, Mazdak Salavati, Claire D. Wathes, the Genotype plus Environment Consortium
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background Previous studies have identified many immune pathways which are consistently altered in humans and model organisms as they age. Dairy cows are often culled at quite young ages due to an inability to cope adequately with metabolic
Externí odkaz:
https://doaj.org/article/a69645746c7d452c8c4395b6fe39de4c
Publikováno v:
Genes, Vol 13, Iss 9, p 1595 (2022)
Copy number variations (CNVs) are genomic structural variants with potential functional and evolutionary effects on phenotypes. In this study, we report the identification and characterization of CNVs from the whole-genome resequencing data of two no
Externí odkaz:
https://doaj.org/article/dbe2d7acf85a44149af96220e84b4438
Autor:
Zhangrui Cheng, Sergio Palma-Vera, Laura Buggiotti, Mazdak Salavati, Frank Becker, Dirk Werling, D. Claire Wathes, GplusE Consortium
Publikováno v:
Animals, Vol 12, Iss 16, p 2146 (2022)
The risk and severity of clinical infection with Escherichia coli as a causative pathogen for bovine mastitis is influenced by the hosts’ phenotypic and genotypic variables. We used RNA-Seq analysis of circulating leukocytes to investigate global t
Externí odkaz:
https://doaj.org/article/db23cd95ad56429aae8733bb17aac5be
Publikováno v:
Viruses, Vol 12, Iss 12, p 1451 (2020)
Microbial RNA is detectable in host samples by aligning unmapped reads from RNA sequencing against taxon reference sequences, generating a score proportional to the microbial load. An RNA-Seq data analysis showed that 83.5% of leukocyte samples from
Externí odkaz:
https://doaj.org/article/3a56683cf5224552bbf430bd6bc8e46e
Autor:
Giulietta Minozzi, Laura Buggiotti, Alessandra Stella, Francesco Strozzi, Mario Luini, John L Williams
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11117 (2010)
BackgroundMycobacterium avium subsp. paratuberculosis (MAP) causes chronic enteritis in a wide range of animal species. In cattle, MAP causes a chronic disease called Johne's disease, or paratuberculosis, that is not treatable and the efficacy of vac
Externí odkaz:
https://doaj.org/article/ac9b29b7a5b443b486ae4b6a880622e1
Autor:
Haruko Takeda, Cinzia Marchitelli, Laura Buggiotti, Sergio Eliseo Palma Vera, Roisin O'Flaherty, Zhangrui Cheng, D Claire Wathes, Alessandra Crisà, Dirk Werling, HEDI HAMMAMI, Tine Rousing, Mazdak Salavati, Federica Signorelli, Mark Crowe, Leslie Foldager, Lijing Tang
Publikováno v:
2021, ' Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis ', Molecular biology reports . https://doi.org/10.1007/s11033-021-06494-8
Cheng, Z, Buggiotti, L, Salavati, M, Marchitelli, C, Palma-Vera, S, Wylie, A, Takeda, H, Tang, L, Crowe, M A, Wathes, D C & GplusE Consortium 2021, ' Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis ', Molecular Biology Reports, vol. 48, pp. 4611-4623 . https://doi.org/10.1007/s11033-021-06494-8
Cheng, Z, Buggiotti, L, Salavati, M, Marchitelli, C, Palma-Vera, S, Wylie, A, Takeda, H, Tang, L, Crowe, M A, Wathes, D C & GplusE Consortium 2021, ' Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis ', Molecular Biology Reports, vol. 48, pp. 4611-4623 . https://doi.org/10.1007/s11033-021-06494-8
BackgroundBovine mastitis, an inflammatory disease of the mammary gland, is classified as subclinical or clinical. Circulating neutrophils are recruited to the udder to combat infection. We compared the transcriptomic profiles in circulating leukocyt
Publikováno v:
The Veterinary record. 190(9)
This research seeks to understand how the transition to a new generation of younger, more diverse farmers affects disease prevention efforts on UK farms.We apply multivariate regression analysis to analyse survey responses from 112 Welsh cattle farm
Autor:
Lijing Tang, Cinzia Marchitelli, Federica Signorelli, Zhangrui Cheng, Klaus Lønne Ingvartsen, Miel Hostens, Haruko Takeda, Leslie Foldager, Frank Becker, Conrad Ferris, D. Claire Wathes, Mazdak Salavati, Clément Grelet, Mark A. Crowe, Laura Buggiotti
Publikováno v:
Wathes, D C, Becker, F, Buggiotti, L, Crowe, M A, Ferris, C P, Foldager, L, Grelet, C, Hostens, M, Ingvartsen, K L, Marchitelli, C, Salavati, M, Signorelli, F, Takeda, H, Tang, L, Cheng, Z & GplusE Consortium 2021, ' Associations between circulating IGF-1 concentrations, disease status and the leukocyte transcriptome in early lactation dairy cows ', Ruminants, vol. 1, no. 2, pp. 147-177 . https://doi.org/10.3390/ruminants1020012
Ruminants; Volume 1; Issue 2; Pages: 147-177
Ruminants; Volume 1; Issue 2; Pages: 147-177
Peripartum dairy cows commonly experience negative energy balance (EB) and immunosuppression together with high incidences of infectious and metabolic disease. This study investigated mechanisms linking EB status with immune defense in early lactatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3728a0fd72830b0d07d64fd9d71f68cd
https://pure.au.dk/portal/da/publications/associations-between-circulating-igf1-concentrations-disease-status-and-the-leukocyte-transcriptome-in-early-lactation-dairy-cows(df4ae2e8-3b6d-47a8-9c9b-5fb5957b0c9b).html
https://pure.au.dk/portal/da/publications/associations-between-circulating-igf1-concentrations-disease-status-and-the-leukocyte-transcriptome-in-early-lactation-dairy-cows(df4ae2e8-3b6d-47a8-9c9b-5fb5957b0c9b).html
Autor:
Cinzia Marchitelli, Laura Buggiotti, Frank Becker, Zhangrui Cheng, D Claire Wathes, Dirk Werling, Tine Rousing, Mazdak Salavati, Leslie Foldager
Publikováno v:
Cheng, Z, Palma-Vera, S, Buggiotti, L, Salavati, M, Becker, F, Werling, D, Wathes, D C & The GplusE consortium 2022, ' Transcriptomic analysis of circulating leukocytes obtained during the recovery from clinical mastitis caused by Escherichia coli in Holstein dairy cows ', Animals, vol. 12, no. 16, 2146 . https://doi.org/10.3390/ani12162146
Cheng, Z, Palma-Vera, S, Buggiotti, L, Salavati, M, Becker, F, Werling, D, Wathes, D C & GplusE Consortium 2022, ' Transcriptomic analysis of circulating leukocytes obtained during the recovery from clinical mastitis caused by escherichia coli in Holstein dairy cows ', Animals, vol. 12, no. 16, 2146, pp. 1-22 . https://doi.org/10.3390/ani12162146
Animals; Volume 12; Issue 16; Pages: 2146
Cheng, Z, Palma-Vera, S, Buggiotti, L, Salavati, M, Becker, F, Werling, D, Wathes, D C & GplusE Consortium 2022, ' Transcriptomic analysis of circulating leukocytes obtained during the recovery from clinical mastitis caused by escherichia coli in Holstein dairy cows ', Animals, vol. 12, no. 16, 2146, pp. 1-22 . https://doi.org/10.3390/ani12162146
Animals; Volume 12; Issue 16; Pages: 2146
The risk and severity of clinical infection with Escherichia coli as a causative pathogen for bovine mastitis is influenced by the hosts’ phenotypic and genotypic variables. We used RNA-Seq analysis of circulating leukocytes to investigate global t