Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Laura Brulle-Soumare"'
Autor:
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Olivier Déas, Judith Michels, Laura Brulle-Soumare, Stefano Cairo, Jean-Yves Scoazec, Virginie Marty, Agathe Aberlenc, David Planchard, Jordi Remon, Santiago Ponce, Benjamin Besse, Patricia L. Kannouche, Jean-Gabriel Judde, Patrycja Pawlikowska, Françoise Farace
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
DNA damage and genomic instability contribute to non–small cell lung cancer (NSCLC) etiology and progression. However, their therapeutic exploitation is disappointing. CTC-derived explants (CDX) offer systems for mechanistic investigation of CTC me
Externí odkaz:
https://doaj.org/article/e641159387994f2a91ffabd1b17d0b73
Autor:
Vincent Faugeroux, Emma Pailler, Marianne Oulhen, Olivier Deas, Laura Brulle-Soumare, Céline Hervieu, Virginie Marty, Kamelia Alexandrova, Kiki C. Andree, Nikolas H. Stoecklein, Dominique Tramalloni, Stefano Cairo, Maud NgoCamus, Claudio Nicotra, Leon W. M. M. Terstappen, Nicolo Manaresi, Valérie Lapierre, Karim Fizazi, Jean-Yves Scoazec, Yohann Loriot, Jean-Gabriel Judde, Françoise Farace
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Better tumor models are needed for the neuroendocrine subtype of castration resistant prostate cancer (CRPC-NE). Here, the authors develop patient-derived model from circulating tumor cells of a CRPC-NE patient, and provide insights on the sequential
Externí odkaz:
https://doaj.org/article/3ccca0e5b5dc46c78df201565348528a
Autor:
Chiara Agnoletto, Linda Minotti, Laura Brulle-Soumare, Lorenzo Pasquali, Marco Galasso, Fabio Corrà, Federica Baldassari, Jean-Gabriel Judde, Stefano Cairo, Stefano Volinia
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract Background We aim to characterize the heterogeneous circulating tumour cells (CTCs) in peripheral blood, independently of physical or immunological purification, by using patient-derived xenografts (PDXs) models. CTC studies from blood gener
Externí odkaz:
https://doaj.org/article/4577d878adb24b779c1893d4915031f6
Autor:
William G. Kaelin, Simon T. Barry, Christopher J. Lord, Susan Ashton, David Pellman, Sabina Signoretti, David E. Root, Jon Travers, Kim Maratea, Elizabeth J. Pease, Colm J. Ryan, Stefano Cairo, Paula Taylor, Laura Brulle-Soumare, Quang-De Nguyen, Dennis M. Bonal, Glenn S. Cowley, Samuel K. McBrayer, Scott T. Younger, Elizabeth Buss, Aditi Gulati, Jesse S. Novak, Abdallah Flaifel, Rebecca B. Jennings, Alexander Spektor, Rachel Brough, Abhishek A. Chakraborty, Raquel Fonseca, Matthew G. Oser
Supplementary Table S5 shows RNA sequencing data and gene set enrichment analysis of NCI-H82 cells Dox-On pRB cells grown in the presence or absence of DOX and then treated with DMSO or AZD2811.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86489d55cf16ceed89defe77d5f66d58
https://doi.org/10.1158/2159-8290.22533007.v1
https://doi.org/10.1158/2159-8290.22533007.v1
Autor:
William G. Kaelin, Simon T. Barry, Christopher J. Lord, Susan Ashton, David Pellman, Sabina Signoretti, David E. Root, Jon Travers, Kim Maratea, Elizabeth J. Pease, Colm J. Ryan, Stefano Cairo, Paula Taylor, Laura Brulle-Soumare, Quang-De Nguyen, Dennis M. Bonal, Glenn S. Cowley, Samuel K. McBrayer, Scott T. Younger, Elizabeth Buss, Aditi Gulati, Jesse S. Novak, Abdallah Flaifel, Rebecca B. Jennings, Alexander Spektor, Rachel Brough, Abhishek A. Chakraborty, Raquel Fonseca, Matthew G. Oser
This document contains the text for the supplementary data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5732b09751dfedc3f31258a710153e32
https://doi.org/10.1158/2159-8290.22533001
https://doi.org/10.1158/2159-8290.22533001
Autor:
William G. Kaelin, Simon T. Barry, Christopher J. Lord, Susan Ashton, David Pellman, Sabina Signoretti, David E. Root, Jon Travers, Kim Maratea, Elizabeth J. Pease, Colm J. Ryan, Stefano Cairo, Paula Taylor, Laura Brulle-Soumare, Quang-De Nguyen, Dennis M. Bonal, Glenn S. Cowley, Samuel K. McBrayer, Scott T. Younger, Elizabeth Buss, Aditi Gulati, Jesse S. Novak, Abdallah Flaifel, Rebecca B. Jennings, Alexander Spektor, Rachel Brough, Abhishek A. Chakraborty, Raquel Fonseca, Matthew G. Oser
Supplementary Figure S1 shows RB1 is synthetic lethal with multiple genes that regulate chromosomal segregation. Supplementary Figure S2 shows genetic inactivation of AURKB is synthetic lethal with RB1 loss in NCI-H82 cells. Supplementary Figure S3 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9edcc3ee48d8078c48fd9b3d57494e
https://doi.org/10.1158/2159-8290.22533022
https://doi.org/10.1158/2159-8290.22533022
Autor:
Delphine Nicolle, Laura Brulle-Soumare, Katell Mevel, Ludovic Bigot, Tala Tayoun, Benjamin Besse, Françoise Farace, Luc Friboulet, Didier Decaudin, Erwan Corcuff, Anaïs Joachim, Bernard Malissen, Ana Zarubica, Hervé Luche, Jean-Gabriel Judde, Olivier Deas
Publikováno v:
Cancer Research. 83:4678-4678
Lung cancer remains the first cause of cancer-related deaths worldwide, of which Non-Small Cell Lung Cancer (NSCLC) represents more than 80% of patients with advanced disease at the time of diagnosis. NSCLC is a highly heterogenous disease, and the i
Autor:
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Olivier Déas, Judith Michels, Laura Brulle-Soumare, Stefano Cairo, Jean-Yves Scoazec, Virginie Marty, Agathe Aberlenc, David Planchard, Jordi Remon, Santiago Ponce, Benjamin Besse, Patricia L. Kannouche, Jean-Gabriel Judde, Patrycja Pawlikowska, Françoise Farace
Publikováno v:
JCI insight. 7(11)
DNA damage and genomic instability contribute to non-small cell lung cancer (NSCLC) etiology and progression. However, their therapeutic exploitation is disappointing. CTC-derived explants (CDX) offer systems for mechanistic investigation of CTC meta
Autor:
Hui Sun Leong, Lei Shi, Stefano Cairo, Francesca Galuppini, Sudhakar Sahoo, Gianpiero Di Leva, D. Smith, Raymond T. O'Keefe, Laura Brulle-Soumare, Matteo Fassan, Robert Sellers, Kang Zeng, Michela Garofalo, Stefano Volinia, Dave Lee, Athanasios R. Paliouras, Tiziana Monteverde, Peter Magee
Publikováno v:
Shi, L, Magee, P, Fassan, M, Sahoo, S, Leong, H S, Lee, D, Sellers, R, Brullé-Soumaré, L, Cairo, S, Monteverde, T, Volinia, S, Smith, D D, Di Leva, G, Galuppini, F, Paliouras, A R, Zeng, K, O'Keefe, R & Garofalo, M 2021, ' A KRAS-responsive long non-coding RNA controls microRNA processing ', Nature Communications, vol. 12, no. 1, 2038 . https://doi.org/10.1038/s41467-021-22337-3
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Wild-type KRAS (KRASWT) amplification has been shown to be a secondary means of KRAS activation in cancer and associated with poor survival. Nevertheless, the precise role of KRASWT overexpression in lung cancer progression is largely unexplored. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d51af05ca11b5e8f61a88aae8dfc0a6
https://research.manchester.ac.uk/en/publications/fcd71e42-cd3e-484c-ace9-15a3be402407
https://research.manchester.ac.uk/en/publications/fcd71e42-cd3e-484c-ace9-15a3be402407
Autor:
Quang-Dé Nguyen, Colm J. Ryan, Matthew G. Oser, Elizabeth Janet Pease, Dennis M. Bonal, William G. Kaelin, David E. Root, Susan Ashton, Simon T. Barry, Aditi Gulati, Paula Taylor, David Pellman, Kim Maratea, Rebecca B. Jennings, Laura Brulle-Soumare, Christopher J. Lord, Jon Travers, Rachel Brough, Scott T. Younger, Raquel Fonseca, Glenn S. Cowley, Stefano Cairo, Jesse Novak, Abdallah Flaifel, Elizabeth J. Buss, Samuel K. McBrayer, Alexander Spektor, Abhishek A. Chakraborty, Sabina Signoretti
Publikováno v:
Cancer Discovery. 9:230-247
Small cell lung cancer (SCLC) accounts for 15% of lung cancers and is almost always linked to inactivating RB1 and TP53 mutations. SCLC frequently responds, albeit briefly, to chemotherapy. The canonical function of the RB1 gene product RB1 is to rep