Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Laura Brulle"'
Autor:
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Olivier Déas, Judith Michels, Laura Brulle-Soumare, Stefano Cairo, Jean-Yves Scoazec, Virginie Marty, Agathe Aberlenc, David Planchard, Jordi Remon, Santiago Ponce, Benjamin Besse, Patricia L. Kannouche, Jean-Gabriel Judde, Patrycja Pawlikowska, Françoise Farace
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
DNA damage and genomic instability contribute to non–small cell lung cancer (NSCLC) etiology and progression. However, their therapeutic exploitation is disappointing. CTC-derived explants (CDX) offer systems for mechanistic investigation of CTC me
Externí odkaz:
https://doaj.org/article/e641159387994f2a91ffabd1b17d0b73
Autor:
Vincent Faugeroux, Emma Pailler, Marianne Oulhen, Olivier Deas, Laura Brulle-Soumare, Céline Hervieu, Virginie Marty, Kamelia Alexandrova, Kiki C. Andree, Nikolas H. Stoecklein, Dominique Tramalloni, Stefano Cairo, Maud NgoCamus, Claudio Nicotra, Leon W. M. M. Terstappen, Nicolo Manaresi, Valérie Lapierre, Karim Fizazi, Jean-Yves Scoazec, Yohann Loriot, Jean-Gabriel Judde, Françoise Farace
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Better tumor models are needed for the neuroendocrine subtype of castration resistant prostate cancer (CRPC-NE). Here, the authors develop patient-derived model from circulating tumor cells of a CRPC-NE patient, and provide insights on the sequential
Externí odkaz:
https://doaj.org/article/3ccca0e5b5dc46c78df201565348528a
Autor:
Chiara Agnoletto, Linda Minotti, Laura Brulle-Soumare, Lorenzo Pasquali, Marco Galasso, Fabio Corrà, Federica Baldassari, Jean-Gabriel Judde, Stefano Cairo, Stefano Volinia
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract Background We aim to characterize the heterogeneous circulating tumour cells (CTCs) in peripheral blood, independently of physical or immunological purification, by using patient-derived xenografts (PDXs) models. CTC studies from blood gener
Externí odkaz:
https://doaj.org/article/4577d878adb24b779c1893d4915031f6
Autor:
William G. Kaelin, Simon T. Barry, Christopher J. Lord, Susan Ashton, David Pellman, Sabina Signoretti, David E. Root, Jon Travers, Kim Maratea, Elizabeth J. Pease, Colm J. Ryan, Stefano Cairo, Paula Taylor, Laura Brulle-Soumare, Quang-De Nguyen, Dennis M. Bonal, Glenn S. Cowley, Samuel K. McBrayer, Scott T. Younger, Elizabeth Buss, Aditi Gulati, Jesse S. Novak, Abdallah Flaifel, Rebecca B. Jennings, Alexander Spektor, Rachel Brough, Abhishek A. Chakraborty, Raquel Fonseca, Matthew G. Oser
Supplementary Table S2 shows Raw NGS reads and Log2 Norm Scores from Illumina sequencing of the pRB synthetic lethal screen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a458a7799f1c29f96364db5b253ee2d
https://doi.org/10.1158/2159-8290.22533016
https://doi.org/10.1158/2159-8290.22533016
Autor:
William G. Kaelin, Simon T. Barry, Christopher J. Lord, Susan Ashton, David Pellman, Sabina Signoretti, David E. Root, Jon Travers, Kim Maratea, Elizabeth J. Pease, Colm J. Ryan, Stefano Cairo, Paula Taylor, Laura Brulle-Soumare, Quang-De Nguyen, Dennis M. Bonal, Glenn S. Cowley, Samuel K. McBrayer, Scott T. Younger, Elizabeth Buss, Aditi Gulati, Jesse S. Novak, Abdallah Flaifel, Rebecca B. Jennings, Alexander Spektor, Rachel Brough, Abhishek A. Chakraborty, Raquel Fonseca, Matthew G. Oser
This document contains the text for the supplementary data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5732b09751dfedc3f31258a710153e32
https://doi.org/10.1158/2159-8290.22533001
https://doi.org/10.1158/2159-8290.22533001
Autor:
William G. Kaelin, Simon T. Barry, Christopher J. Lord, Susan Ashton, David Pellman, Sabina Signoretti, David E. Root, Jon Travers, Kim Maratea, Elizabeth J. Pease, Colm J. Ryan, Stefano Cairo, Paula Taylor, Laura Brulle-Soumare, Quang-De Nguyen, Dennis M. Bonal, Glenn S. Cowley, Samuel K. McBrayer, Scott T. Younger, Elizabeth Buss, Aditi Gulati, Jesse S. Novak, Abdallah Flaifel, Rebecca B. Jennings, Alexander Spektor, Rachel Brough, Abhishek A. Chakraborty, Raquel Fonseca, Matthew G. Oser
Supplementary Figure S1 shows RB1 is synthetic lethal with multiple genes that regulate chromosomal segregation. Supplementary Figure S2 shows genetic inactivation of AURKB is synthetic lethal with RB1 loss in NCI-H82 cells. Supplementary Figure S3 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9edcc3ee48d8078c48fd9b3d57494e
https://doi.org/10.1158/2159-8290.22533022
https://doi.org/10.1158/2159-8290.22533022
Autor:
Delphine Nicolle, Laura Brulle-Soumare, Katell Mevel, Ludovic Bigot, Tala Tayoun, Benjamin Besse, Françoise Farace, Luc Friboulet, Didier Decaudin, Erwan Corcuff, Anaïs Joachim, Bernard Malissen, Ana Zarubica, Hervé Luche, Jean-Gabriel Judde, Olivier Deas
Publikováno v:
Cancer Research. 83:4678-4678
Lung cancer remains the first cause of cancer-related deaths worldwide, of which Non-Small Cell Lung Cancer (NSCLC) represents more than 80% of patients with advanced disease at the time of diagnosis. NSCLC is a highly heterogenous disease, and the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d98b8a9c28a3ffbc8131ecb9bc9d02
https://doi.org/10.1158/1538-7445.am2023-4678
https://doi.org/10.1158/1538-7445.am2023-4678
Autor:
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Olivier Déas, Judith Michels, Laura Brulle-Soumare, Stefano Cairo, Jean-Yves Scoazec, Virginie Marty, Agathe Aberlenc, David Planchard, Jordi Remon, Santiago Ponce, Benjamin Besse, Patricia L. Kannouche, Jean-Gabriel Judde, Patrycja Pawlikowska, Françoise Farace
Publikováno v:
JCI insight. 7(11)
DNA damage and genomic instability contribute to non-small cell lung cancer (NSCLC) etiology and progression. However, their therapeutic exploitation is disappointing. CTC-derived explants (CDX) offer systems for mechanistic investigation of CTC meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bc965137ecf5dac982fde738aad867
https://pubmed.ncbi.nlm.nih.gov/35511434
https://pubmed.ncbi.nlm.nih.gov/35511434
Autor:
Quang-Dé Nguyen, Colm J. Ryan, Matthew G. Oser, Elizabeth Janet Pease, Dennis M. Bonal, William G. Kaelin, David E. Root, Susan Ashton, Simon T. Barry, Aditi Gulati, Paula Taylor, David Pellman, Kim Maratea, Rebecca B. Jennings, Laura Brulle-Soumare, Christopher J. Lord, Jon Travers, Rachel Brough, Scott T. Younger, Raquel Fonseca, Glenn S. Cowley, Stefano Cairo, Jesse Novak, Abdallah Flaifel, Elizabeth J. Buss, Samuel K. McBrayer, Alexander Spektor, Abhishek A. Chakraborty, Sabina Signoretti
Publikováno v:
Cancer Discovery. 9:230-247
Small cell lung cancer (SCLC) accounts for 15% of lung cancers and is almost always linked to inactivating RB1 and TP53 mutations. SCLC frequently responds, albeit briefly, to chemotherapy. The canonical function of the RB1 gene product RB1 is to rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af292a270daec29d1e42e6631694227
https://doi.org/10.1158/2159-8290.cd-18-0389
https://doi.org/10.1158/2159-8290.cd-18-0389
Autor:
Laura Brulle-Soumare, Ludovic Bigot, Katell Mevel, Enora Le Ven, Luc Friboulet, Benjamin Besse, Françoise Farace, Jean Gabriel Judde, Stefano Cairo, Yohann Loriot, Olivier Déas
Publikováno v:
Cancer Research. 82:3113-3113
Prostate Cancer (PCa) is the most frequently diagnosed cancer in men and remains one of the leading causes of cancer death worldwide. It is a highly heterogenous and complex disease, presenting serious challenges to preclinical drug development and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6936417aa3a2db5a6cf70ffb581dbc6
https://doi.org/10.1158/1538-7445.am2022-3113
https://doi.org/10.1158/1538-7445.am2022-3113