Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Brudecki"'
Autor:
Charles E. McCall, Mohamed El Gazzar, Melissa M. Berrien-Elliott, Cheng-Chin Kuo, Miriam H. P. van Lieshout, Diane Ly, Joseph C. Sun, Krishna Rajarathnam, Roberto P. Garofalo, Peter Chen, Zhi Q. Yao, Meng Li, Jude M. Taylor, Laura Brudecki, Renling Xu, Elena Sbrana, Eva Medina, Robert H. Cox, Tom van der Poll, Jian-Jie Li, Julia A. Wagner, Shuai Wang, Clara McClure, Hao Yan, Todd A. Fehniger, Sandrine Florquin, Hal K. Hawkins, Martina L. Sanderson-Smith, Alex F. de Vos, Druckerei Stückle, Manfred Rohde, Sebastian Voigt, James A. Tsatsaronis, Mark J. Walker, Oscar A. Aguilar, James R. Carlyle, Aleta Pupovac, Timothy E. O’Sullivan, Chong He, Hai-Qiong Yu, Ping-Chang Yang, Jaehun Ma, Aruz Mesci, Deepthi Kolli, Zhan-Ju Liu, David S.J. Allan, Joachim Hundrieser, Lei-Lei Fang, Cornelis vanʼt Veer, Rui-Jin Wu, Jing-Yiing Wu, Christina L. Kirkham, Satz Mengensatzproduktion, Oliver Goldmann, Kirti V. Sawant, Zhi-Gang Liu
Publikováno v:
Journal of Innate Immunity. 7:I-IV
Autor:
Donald A. Ferguson, Laura Brudecki, Jonathan P. Moorman, Zhi Q. Yao, Mohamed El Gazzar, Clara McClure, Charles E. McCall
Publikováno v:
Infection and Immunity. 82:3816-3825
The sepsis initial hyperinflammatory reaction, if not treated early, shifts to a protracted state of immunosuppression that alters both innate and adaptive immunity and is associated with elevated mortality. Myeloid-derived suppressor cells (MDSCs) a
Publikováno v:
Immunology and cell biology
Within hours after its initiation, the severe systemic inflammatory response of sepsis shifts to an adaptive anti-inflammatory state with coincident immunosuppression. This anti-inflammatory phenotype is characterized by diminished proinflammatory cy
Publikováno v:
Infection and Immunity. 80:2026-2034
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous Gr1 + CD11b + population of immature cells containing granulocytic and monocytic progenitors, which expand under nearly all inflammatory conditions and are potent repressors of T-cell respo
Publikováno v:
Archives of Biochemistry and Biophysics. 471:168-175
The role of alphaPhe-291 residue in phosphate binding by Escherichia coli F1F0-ATP synthase was examined. X-ray structures of bovine mitochondrial enzyme suggest that this residue resides in close proximity to the conserved betaR246 residue. Herein,
Publikováno v:
Journal of innate immunity. 7(6)
An anti-inflammatory phenotype with pronounced immunosuppression develops during sepsis, during which time neutrophils and monocytes/macrophages limit their Toll-like receptor 4 responses to bacterial lipopolysaccharide (LPS/endotoxin). We previously
Autotoxic production of proinflammatory mediators during early sepsis induces excessive inflammation, and their later suppression may limit the immune response. We previously reported that sepsis differentially represses transcription and translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378ec3360db3b0bb07af3bf4688a2506
https://europepmc.org/articles/PMC3889586/
https://europepmc.org/articles/PMC3889586/
Publikováno v:
Immunology and cell biology. 90(10)
Effective treatment of the acute systemic inflammatory response associated with sepsis is lacking, but likely will require new ways to rebalance dysregulated immune responses. One challenge is that human sepsis often is diagnosed too late to reduce t
Autor:
Mohamed El Gazzar, Donald A. Ferguson, Deling Yin, Gene LeSage, Laura Brudecki, Charles E. McCall
Publikováno v:
Infection and immunity. 80(2)
Sepsis progresses from an early/acute hyperinflammatory to a late/chronic hypoinflammatory phase with immunosuppression. As a result of this phenotypic switch, mortality in late sepsis from persistent primary infection or opportunistic new infection
Autor:
Zulfiqar Ahmad, Laura Brudecki
Publikováno v:
The FASEB Journal. 24