Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Brabenec"'
Autor:
Finnja Marie Zurek-Leffers, Florian Lehmann, Laura Brabenec, Sebastian Kintrup, Katharina E. M. Hellenthal, Kira Mersjann, Felicia Kneifel, Michael Hessler, Philip-Helge Arnemann, Tim-Gerald Kampmeier, Christian Ertmer, Patrick Kellner, Nana-Maria Wagner
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality of patients with sepsis is high and largely unchanged throughout the past decades. Animal models have been widely used f
Externí odkaz:
https://doaj.org/article/9cdf58be157e47a280820934947edbd1
A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents
Autor:
Shufang He, Vanessa O. Zambelli, Pritam Sinharoy, Laura Brabenec, Yang Bian, Freeborn Rwere, Rafaela C.R. Hell, Beatriz Stein Neto, Barbara Hung, Xuan Yu, Meng Zhao, Zhaofei Luo, Chao Wu, Lijun Xu, Katrin J. Svensson, Stacy L. McAllister, Creed M. Stary, Nana-Maria Wagner, Ye Zhang, Eric R. Gross
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
Pain signals are relayed to the brain via a nociceptive system, and in rare cases, this nociceptive system contains genetic variants that can limit the pain response. Here, we questioned whether a human transient receptor potential vanilloid 1 (TRPV1
Externí odkaz:
https://doaj.org/article/37d0f51fb16d49a8b7cc88f9c3a78b93
Publikováno v:
Cells, Vol 11, Iss 12, p 1935 (2022)
Systemic inflammation can be triggered by infection, surgery, trauma or burns. During systemic inflammation, an overshooting immune response induces tissue damage resulting in organ dysfunction and mortality. Endothelial cells make up the inner linin
Externí odkaz:
https://doaj.org/article/961fa83986d54406bd0cb4860a9ee3cd
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1401 (2021)
The transient receptor potential (TRP) cation channel superfamily comprises more than 50 channels that play crucial roles in physiological processes. TRP channels are responsive to several exogenous and endogenous biomolecules, with aldehydes emergin
Externí odkaz:
https://doaj.org/article/e75c72fb664149f8a40467debda9f321
A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents
Autor:
Shufang He, Vanessa O. Zambelli, Pritam Sinharoy, Laura Brabenec, Yang Bian, Freeborn Rwere, Rafaela C.R. Hell, Beatriz Stein Neto, Barbara Hung, Xuan Yu, Meng Zhao, Zhaofei Luo, Chao Wu, Lijun Xu, Katrin J. Svensson, Stacy L. McAllister, Creed M. Stary, Nana-Maria Wagner, Ye Zhang, Eric R. Gross
Publikováno v:
The Journal of clinical investigation.
Pain signals are relayed to the brain via a nociceptive system, and in rare situations, this nociceptive system contains genetic variants that can limit pain response. Here we questioned whether a human transient receptor potential vanilloid 1 (TRPV1
Autor:
Laura Brabenec, Katharina E.M. Hellenthal, Melanie Müller, Sebastian Kintrup, Finnja Zurek-Leffers, Marina Kardell, Mandy Otto, Nana-Maria Wagner
Publikováno v:
Life sciences. 307
Obesity is accompanied by a chronic low-grade inflammation associated with endothelial dysfunction and vascular complications. Procalcitonin is a marker of inflammation, secreted by adipose tissue and elevated in obese subjects. We here investigated
Autor:
Laura Brabenec, Melanie Müller, Katharina E. M. Hellenthal, Ole S. Karsten, Heorhii Pryvalov, Mandy Otto, Anna Holthenrich, Anna L. Linard Matos, Raphael Weiss, Sebastian Kintrup, Michael Hessler, Angelo Dell’Aquila, Katharina Thomas, Johannes Naß, Andreas Margraf, Astrid F. Nottebaum, Jan Rossaint, Alexander Zarbock, Dietmar Vestweber, Volker Gerke, Nana-Maria Wagner
Publikováno v:
American journal of respiratory and critical care medicine. 206(4)
Publikováno v:
Biomolecules, Vol 11, Iss 1401, p 1401 (2021)
Biomolecules
Biomolecules
The transient receptor potential (TRP) cation channel superfamily comprises more than 50 channels that play crucial roles in physiological processes. TRP channels are responsive to several exogenous and endogenous biomolecules, with aldehydes emergin
Autor:
Jan Rossaint, Katharina E. M. Hellenthal, Sophie Charlotte Steinbuch, Ole Sönken Karsten, Nana-Maria Wagner, Melanie J. I. Müller, Heorhii Pryvalov, Mandy Otto, Eric R. Gross, Sebastian Kintrup, Laura Brabenec, Richard Holtmeier
Publikováno v:
Life Sci
Aims H eart f ailure with p reserved e jection f raction (HFpEF) is associated with endothelial dysfunction and is frequent in people with type 2 diabetes mellitus. In diabetic patients, increased levels of the eicosanoid 12-hydroxyeicosatetraenoic a
Publikováno v:
Planta Med
BNO 1095, a standardized dry extract from the fruits of Vitex agnus-castus, represents an approved herbal medicinal product for the treatment of premenstrual syndrome. Angiogenesis, the formation of new blood vessels from pre-existing capillaries, pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1092ff87cb2e579f6a2012b54b2a58e1
https://europepmc.org/articles/PMC8277439/
https://europepmc.org/articles/PMC8277439/