LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton

Autor: Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Natalia Martín-Martín, Amaia Ercilla, Jose A. Rodríguez, Arkaitz Carracedo, James D. Sutherland, Rosa Barrio

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

LUZP1 is a centrosomal and actin cytoskeleton-localizing protein that regulates both ciliogenesis and actin filament bundling. As the cytoskeleton and cilia are implicated in metastasis and tumor suppression, we examined roles for LUZP1 in the contex

Externí odkaz: https://doaj.org/article/f2e2f686b33d4a4c8682e5ca39f15153

Virtual meeting, real and sound science: report of the 17 th Meeting of the Spanish Society for Developmental Biology (SEBD-2020)

Autor: Sofia J. Araújo, Sergio Casas-Tintó, James Sharpe, Alvaro Rada-Iglesias, Rosa Barrio, Fernando García-Moreno, Cristina Villa del Campo, Oscar H. Ocaña, Teresa Rayon, Luciano Marcon, Fernando Casares, James D. Sutherland, Ignacio Maeso, Olatz Pampliega, Maria Losada-Perez, Augusto Escalante, Laura Bozal-Basterra, Isabel Almudi

The Spanish Society for Developmental Biology (SEBD) organized its 17th meeting in November 2020 (herein referred to as SEBD2020). This meeting, originally programmed to take place in the city of Bilbao, was forced onto an online format due to the SA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf63bb3601e13f2b2ad49cb3417e18d8
http://hdl.handle.net/10230/52697

LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome

Autor: Jose Antonio Rodriguez, Carolina Da Fonseca, Orhi Barroso-Gomila, Laura Bozal-Basterra, Tess C. Branon, Olatz Pampliega, María Gonzalez-Santamarta, Aitor Bermejo-Arteagabeitia, Veronica Muratore, Natalia Martín-Martín, Felix Elortza, James D. Sutherland, Alice Y. Ting, Ibon Iloro, Rosa Barrio, Ricardo Andrade, Mikel Azkargorta, Arkaitz Carracedo

Publikováno v: eLife, Vol 9 (2020)
eLife

Primary cilia are sensory organelles crucial for cell signaling during development and organ homeostasis. Cilia arise from centrosomes and their formation and function is governed by numerous factors. Through our studies on Townes-Brocks Syndrome (TB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08dc88358d48b89b00ee4bce39ddbbe3
https://elifesciences.org/articles/55957

Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood

Autor: Laura Bozal Basterra, Peter Meerlo, Nieske Brouwer, Anne Schaafsma, Wandert Schaafsma, Bart J. L. Eggen, Sabrina Jacobs, Erik Boddeke

Publikováno v: Neurobiology of Disease, Vol 106, Iss, Pp 291-300 (2017)
Neurobiology of Disease, 106, 291-300. ACADEMIC PRESS INC ELSEVIER SCIENCE

Maternal inflammation during pregnancy can have detrimental effects on embryonic development that persist during adulthood. However, the underlying mechanisms and insights in the responsible cell types are still largely unknown. Here we report the ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a30175745bae8d073810a7cde347ff1
https://doi.org/10.1016/j.nbd.2017.07.017

The metabolic co-regulator PGC1α suppresses prostate cancer metastasis

Autor: Patricia Zúñiga-García, Jason W. Locasale, Marc Guiu, M. Unda-Urzaiz, Mireia Castillo-Martin, Rosa Barrio, Amaia Zabala-Letona, Antonio Berenguer, Verónica Torrano, Alfredo Caro-Maldonado, Mar Lorente, Carlos Cordon-Cardo, Roger R. Gomis, Nieves Embade, Ana Loizaga-Iriarte, Victoria Sanz-Moreno, Ana R. Cortazar, Guillermo Velasco, Giampaolo Morciano, James D. Sutherland, Anna Bellmunt, Natalia Martín-Martín, Arkaitz Carracedo, Laura Bozal-Basterra, Aitziber Ugalde-Olano, Xiaojing Liu, Sonia Fernández-Ruiz, Amaia Arruabarrena-Aristorena, Lorea Valcarcel-Jimenez, Pilar Sanchez-Mosquera, Jelena Urosevic, Isabel Lacasa-Viscasillas, Paolo Pinton, Nikolaus Schultz, Mariona Graupera, Pahini Pandya, Ana M. Aransay

Publikováno v: Nature cell biology
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Cell Biology
Dipòsit Digital de la UB
Universidad de Barcelona
Torrano, V, Valcarcel-Jimenez, L, Cortazar, A R, Liu, X, Urosevic, J, Castillo-Martin, M, Fernández-Ruiz, S, Morciano, G, Caro-Maldonado, A, Guiu, M, Zúñiga-García, P, Graupera, M, Bellmunt, A, Pandya, P, Lorente, M, Martín-Martín, N, David Sutherland, J, Sanchez-Mosquera, P, Bozal-Basterra, L, Zabala-Letona, A, Arruabarrena-Aristorena, A, Berenguer, A, Embade, N, Ugalde-Olano, A, Lacasa-Viscasillas, I, Loizaga-Iriarte, A, Unda-Urzaiz, M, Schultz, N, Aransay, A M, Sanz-Moreno, V, Barrio, R, Velasco, G, Pinton, P, Cordon-Cardo, C, Locasale, J W, Gomis, R R & Carracedo, A 2016, ' The metabolic co-regulator PGC1α suppresses prostate cancer metastasis ', Nature Cell Biology, vol. 18, no. 6, pp. 645-656 . https://doi.org/10.1038/ncb3357
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Cellular transformation and cancer progression is accompanied by changes in the metabolic landscape. Master co-regulators of metabolism orchestrate the modulation of multiple metabolic pathways through transcriptional programs, and hence constitute a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34f0e9d7610f954a76c2ba87f82ad29
http://europepmc.org/articles/PMC4884178