Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laura Bounti"'
Autor:
Ramanath Narayana Hegde, Seetharaman Parashuraman, Francesco Iorio, Fabiana Ciciriello, Fabrizio Capuani, Annamaria Carissimo, Diego Carrella, Vincenzo Belcastro, Advait Subramanian, Laura Bounti, Maria Persico, Graeme Carlile, Luis Galietta, David Y Thomas, Diego Di Bernardo, Alberto Luini
Publikováno v:
eLife, Vol 4 (2015)
Cystic fibrosis (CF) is caused by mutations in CF transmembrane conductance regulator (CFTR). The most frequent mutation (F508del-CFTR) results in altered proteostasis, that is, in the misfolding and intracellular degradation of the protein. The F508
Externí odkaz:
https://doaj.org/article/539e56c235594b23a5b171eb590f887b
Autor:
Wim Mandemakers, Sabine Kuenen, Vincenzo Bonifati, Sandra-Fausia Soukup, Sven Vilain, Femke M.S. de Vrij, Marina Picillo, Julia Manetsberger, Serguei Gontcharenko, Frederic A. Meunier, Patrik Verstreken, Adekunle T. Bademosi, Nils Schoovaerts, Jef Swerts, Natalia V. Gounko, Roy Masius, Shashini T. Munshi, Steven A. Kushner, Paolo Barone, Roeland Vanhauwaert, Laura Bounti
Publikováno v:
The EMBO Journal
EMBO J
EMBO Journal, 36(10), 1392-1411. Wiley-Blackwell
EMBO J
EMBO Journal, 36(10), 1392-1411. Wiley-Blackwell
Presynaptic terminals are metabolically active and accrue damage through continuous vesicle cycling. How synapses locally regulate protein homeostasis is poorly understood. We show that the presynaptic lipid phosphatase synaptojanin is required for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b70a57c840da8e80bf466cbcbf7cef6
https://doi.org/10.15252/embj.201695773
https://doi.org/10.15252/embj.201695773
Autor:
Tara L. Spires-Jones, Joseph McInnes, Keimpe D. Wierda, Ilie-Cosmin Stancu, Yu-Chun Wang, Nuno Apóstolo, Patrik Verstreken, Joris de Wit, Kris Gevaert, Lujia Zhou, Laura Bounti, Bart De Strooper, Ilse Dewachter, An Snellinx
Publikováno v:
Neuron
Neuron, Vol. 97, no. 4, p. 823-835.e8 (2018)
McInnes, J, Wierda, K, Snellinx, A, Wang, Y-C, Stancu, I-C, Apostolo, N, Gevaert, K, Dewachter, I, Spires-Jones, T, De Strooper, B, De Wit, J, Zhou, L & Verstreken, P 2018, ' Synaptogyrin-3 mediates presynaptic dysfunction induced by Tau ', Neuron . https://doi.org/10.1016/j.neuron.2018.01.022
Neuron, Vol. 97, no. 4, p. 823-835.e8 (2018)
McInnes, J, Wierda, K, Snellinx, A, Wang, Y-C, Stancu, I-C, Apostolo, N, Gevaert, K, Dewachter, I, Spires-Jones, T, De Strooper, B, De Wit, J, Zhou, L & Verstreken, P 2018, ' Synaptogyrin-3 mediates presynaptic dysfunction induced by Tau ', Neuron . https://doi.org/10.1016/j.neuron.2018.01.022
Synaptic dysfunction is an early pathological feature of neurodegenerative diseases associated with Tau, including Alzheimer's disease. Interfering with early synaptic dysfunction may be therapeutically beneficial to prevent cognitive decline and dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980b6bd02bae270864ced08fd93380f6
Autor:
Diego di Bernardo, Diego Carrella, Advait Subramanian, Francesco Iorio, Maria Persico, David Y. Thomas, Ramanath Narayana Hegde, Fabiana Ciciriello, Luis J. V. Galietta, Vincenzo Belcastro, Laura Bounti, Graeme W. Carlile, Alberto Luini, Annamaria Carissimo, Seetharaman Parashuraman, Fabrizio Capuani
Publikováno v:
eLife, Vol 4 (2015)
eLife (2015). doi:10.7554/eLife.10365
info:cnr-pdr/source/autori:Hegde RN, Parashuraman S, Iorio F, Ciciriello F, Capuani F, Carissimo A, Carrella D, Belcastro V, Subramanian A, Bounti L, Persico M, Carlile G, Galietta L, Thomas DY, Di Bernardo D, Luini A/titolo:Unravelling druggable signalling networks that control F508del-CFTR proteostasis./doi:10.7554%2FeLife.10365/rivista:eLife/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume
Europe PubMed Central
eLife
eLife (2015). doi:10.7554/eLife.10365
info:cnr-pdr/source/autori:Hegde RN, Parashuraman S, Iorio F, Ciciriello F, Capuani F, Carissimo A, Carrella D, Belcastro V, Subramanian A, Bounti L, Persico M, Carlile G, Galietta L, Thomas DY, Di Bernardo D, Luini A/titolo:Unravelling druggable signalling networks that control F508del-CFTR proteostasis./doi:10.7554%2FeLife.10365/rivista:eLife/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume
Europe PubMed Central
eLife
Cystic fibrosis (CF) is caused by mutations in CF transmembrane conductance regulator (CFTR). The most frequent mutation (F508del-CFTR) results in altered proteostasis, that is, in the misfolding and intracellular degradation of the protein. The F508
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c3bcf561307649f2ae28c05a9d10cd
https://elifesciences.org/articles/10365
https://elifesciences.org/articles/10365
Autor:
Seetharaman Parashuraman, Fabrizio Capuani, Vincenzo Belcastro, Diego di Bernardo, Alberto Luini, Annamaria Carissimo, Laura Bounti, Diego Carrella, David Y. Thomas, Fabiana Ciciriello, Graeme W. Carlile, Luis J. V. Galietta, Ramanath Narayana Hegde, Advait Subramanian, Francesco Iorio, Maria Persico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55df94bf9b239025fdd414f556fa8a7f
https://doi.org/10.7554/elife.10365.028
https://doi.org/10.7554/elife.10365.028
