Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Laura Bouché"'
Autor:
Yilin Wang, Aneesah Khan, Aristotelis Antonopoulos, Laura Bouché, Christopher D. Buckley, Andrew Filer, Karim Raza, Kun-Ping Li, Barbara Tolusso, Elisa Gremese, Mariola Kurowska-Stolarska, Stefano Alivernini, Anne Dell, Stuart M. Haslam, Miguel A. Pineda
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Dysregulation of synovial fibroblasts is thought to be an important step in the pathogenesis of rheumatoid arthritis. Here the authors implicate α2-6 sialylation in this process by studying the glycome of these cells in patients and in a mouse model
Externí odkaz:
https://doaj.org/article/72dfa842353344fcbc847fcee0909af2
Autor:
Ryan Hunt, Gaya Hettiarachchi, Upendra Katneni, Nancy Hernandez, David Holcomb, Jacob Kames, Redab Alnifaidy, Brian Lin, Nobuko Hamasaki-Katagiri, Aaron Wesley, Tal Kafri, Christina Morris, Laura Bouché, Maria Panico, Tal Schiller, Juan Ibla, Haim Bar, Amra Ismail, Howard Morris, Anton Komar, Chava Kimchi-Sarfaty
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5734 (2019)
Synonymous variants within coding regions may influence protein expression and function. We have previously reported increased protein expression levels ex vivo (~120% in comparison to wild-type) from a synonymous polymorphism variant, c.354G>A [p.P1
Externí odkaz:
https://doaj.org/article/98abfdc5d94c45b38f6c7ef3a3b77122
Autor:
Elizabeth Stansell, Maria Panico, Kevin Canis, Poh-Choo Pang, Laura Bouché, Daniel Binet, Michael-John O'Connor, Elena Chertova, Julian Bess, Jeffrey D Lifson, Stuart M Haslam, Howard R Morris, Ronald C Desrosiers, Anne Dell
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124784 (2015)
As HIV-1-encoded envelope protein traverses the secretory pathway, it may be modified with N- and O-linked carbohydrate. When the gp120s of HIV-1 NL4-3, HIV-1 YU2, HIV-1 Bal, HIV-1 JRFL, and HIV-1 JRCSF were expressed as secreted proteins, the threon
Externí odkaz:
https://doaj.org/article/27d7d92696914ff1a11ff3d9a4512bc0
Autor:
Karim Raza, Christopher D. Buckley, Laura Bouché, Aneesah M. Khan, Mariola Kurowska-Stolarska, Elisa Gremese, Andrew Filer, Miguel A. Pineda, Stuart M. Haslam, Stefano Alivernini, Kun-Ping Li, Aristotelis Antonopoulos, Anne Dell, Yilin Wang, Barbara Tolusso
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
In healthy joints, synovial fibroblasts (SFs) provide the microenvironment required to mediate homeostasis, but these cells adopt a pathological function in rheumatoid arthritis (RA). Carbohydrates (glycans) on cell surfaces are fundamental regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd3575f611c44bd5d5549915bdc1de5
http://europepmc.org/articles/PMC8058094
http://europepmc.org/articles/PMC8058094
Autor:
Aleksei B. Dingel, B.S., Marc Tompkins, M.D., Yi-Meng Yen, M.D., Alexander K. Karius, B.S., Mark Cinque, M.D., Brian B. Vuong, B.S., Vanessa Taylor, B.S., Nicole S. Pham, M.P.H., Theodore J. Ganley, M.D., Philip Wilson, M.D., Henry B. Ellis, M.D., Daniel Green, M.D., Peter D. Fabricant, M.D., Laura Boucher, Ph.D., A.T., A.T.C., Kevin G. Shea, M.D.
Publikováno v:
Arthroscopy, Sports Medicine, and Rehabilitation, Vol 6, Iss 3, Pp 100852- (2024)
Purpose: To define the surgical anatomy of the meniscotibial ligament complex of the pediatric medial and lateral menisci and their relation to the proximal tibial physis and posterior joint capsule. Methods: Fourteen pediatric cadaveric knee specime
Externí odkaz:
https://doaj.org/article/16598681c3e34459a683783c25c75e14
Autor:
Robyn Recker, Alison Myers, Nikhil Desai, Jaclyn B. Caccese, Laura Boucher, James Onate, Jingzhen Yang
Publikováno v:
Frontiers in Sports and Active Living, Vol 6 (2024)
PurposeMandating headgear for field players in girls’ lacrosse to reduce head injuries, including concussion, has been heavily debated. However, research regarding the need and effectiveness of mandated headgear use in girls’ lacrosse is still de
Externí odkaz:
https://doaj.org/article/1e0d7109247d4c5ea546344899e4907d
Autor:
Andrew Filer, Aneesah M. Khan, Miguel A. Pineda, Stuart M. Haslam, Mariola Kurowska-Stolarska, Yilin Wang, Laura Bouché, Kun Ping-Li, Karim Raza, Aristotelis Antonopoulos, Stefano Alivernini, Anne Dell, Barbara Tolusso, Elisa Gremese, Christopher D. Buckley
In healthy joints, synovial fibroblasts (SFs) provide the microenvironment required to mediate homeostasis but are recognized to adopt a pathological role in rheumatoid arthritis (RA), promoting the infiltration and activation of immune cells to perp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c084333d2000a9af531a902205e76f36
https://doi.org/10.1101/2020.03.08.970046
https://doi.org/10.1101/2020.03.08.970046
Autor:
Upendra K. Katneni, Ryan C. Hunt, Juan C. Ibla, Amra Ismail, Chava Kimchi-Sarfaty, Tal Schiller, Gaya K. Hettiarachchi, David D. Holcomb, Laura Bouché, Jacob Kames, Maria Panico, Nobuko Hamasaki-Katagiri, Haim Bar, Howard R. Morris, Christina Morris, Nancy E. Hernandez, Brian Lin, Aaron Wesley, Tal Kafri, Redab Alnifaidy, Anton A. Komar
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5734 (2019)
Synonymous variants within coding regions may influence protein expression and function. We have previously reported increased protein expression levels ex vivo (~120% in comparison to wild-type) from a synonymous polymorphism variant, c.354G>A [p.P1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6463a7fd3dff6fc538d42d1f416166c3
https://doi.org/10.3390/ijms20225734
https://doi.org/10.3390/ijms20225734
Autor:
Laura, Bouché, Maria, Panico, Paul, Hitchen, Daniel, Binet, Federico, Sastre, Alexandra, Faulds-Pain, Esmeralda, Valiente, Evgeny, Vinogradov, Annie, Aubry, Kelly, Fulton, Susan, Twine, Susan M, Logan, Brendan W, Wren, Anne, Dell, Howard R, Morris
Publikováno v:
The Journal of Biological Chemistry
Glycosylation of flagellins is a well recognized property of many bacterial species. In this study, we describe the structural characterization of novel flagellar glycans from a number of hypervirulent strains of C. difficile. We used mass spectromet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01ee2ca145c3af975479743cc29e032a
https://pubmed.ncbi.nlm.nih.gov/27758867
https://pubmed.ncbi.nlm.nih.gov/27758867
Autor:
Maria, Panico, Laura, Bouché, Daniel, Binet, Michael-John, O'Connor, Dinah, Rahman, Poh-Choo, Pang, Kevin, Canis, Simon J, North, Ronald C, Desrosiers, Elena, Chertova, Brandon F, Keele, Julian W, Bess, Jeffrey D, Lifson, Stuart M, Haslam, Anne, Dell, Howard R, Morris
Publikováno v:
Scientific Reports
The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120(SU) plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target. Gp120 has remarkably high levels of N-linked glycosylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbc9bdaa2145248fb33fe7c6b70ca29f
https://pubmed.ncbi.nlm.nih.gov/27604319
https://pubmed.ncbi.nlm.nih.gov/27604319