Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Laura Botana"'
Autor:
Ignacio Hernandez-Navarro, Laura Botana, Javier Diez-Mata, Laura Tesoro, Beatriz Jimenez-Guirado, Claudia Gonzalez-Cucharero, Nunzio Alcharani, Jose Luis Zamorano, Marta Saura, Carlos Zaragoza
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 9890 (2024)
Vascular aging is associated with the development of cardiovascular complications, in which endothelial cell senescence (ES) may play a critical role. Nitric oxide (NO) prevents human ES through inhibition of oxidative stress, and inflammatory signal
Externí odkaz:
https://doaj.org/article/d079a70260a94403936c7b40f27f269f
Autor:
Laura Botana, Ana Victoria Ibarra-Meneses, Carmen Sanchez, Belen Matia, Juan Victor San Martin, Javier Moreno, Eugenia Carrillo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009662 (2021)
Visceral leishmaniasis (VL) in patients receiving immunosuppressant drugs for autoimmune disease has been on the rise. It is important-but difficult-to know when cure has been achieved in these patients since the withdrawal of immunosuppressants duri
Externí odkaz:
https://doaj.org/article/79b394a01ce3498fa073f55eb5423ef2
Autor:
Laura Tesoro, Ignacio Hernández, Rafael Ramírez-Carracedo, Javier Díez-Mata, Nunzio Alcharani, Beatriz Jiménez-Guirado, Karina Ovejero-Paredes, Marco Filice, Jose Luis Zamorano, Marta Saura, Carlos Zaragoza, Laura Botana
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2044 (2022)
(1) Background: Early response after acute myocardial infarction (AMI) prevents extensive cardiac necrosis, in which inflammation resolution, including expression of anti-inflammatory interleukin-10 (IL-10), may play a key role. (2) Methods: We synth
Externí odkaz:
https://doaj.org/article/af73e945a7974b3c919fa1814f74731f
Autor:
Laura Botana, Ana Victoria Ibarra-Meneses, Carmen Sánchez, Alicia Castro, Juan Victor San Martin, Laura Molina, Jose Manuel Ruiz-Giardin, Eugenia Carrillo, Javier Moreno
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007461 (2019)
Concomitant infection with human immunodeficiency virus (HIV) and the Leishmania parasite is a growing public health problem, the result of the former spreading to areas where the latter is endemic. Leishmania infection is usually asymptomatic in imm
Externí odkaz:
https://doaj.org/article/214340e05ad54b5f8d73d0a1bb538d41
Autor:
Giovanni Bussotti, Evi Gouzelou, Mariana Côrtes Boité, Ihcen Kherachi, Zoubir Harrat, Naouel Eddaikra, Jeremy C. Mottram, Maria Antoniou, Vasiliki Christodoulou, Aymen Bali, Fatma Z. Guerfali, Dhafer Laouini, Maowia Mukhtar, Franck Dumetz, Jean-Claude Dujardin, Despina Smirlis, Pierre Lechat, Pascale Pescher, Adil El Hamouchi, Meryem Lemrani, Carmen Chicharro, Ivonne Pamela Llanes-Acevedo, Laura Botana, Israel Cruz, Javier Moreno, Fakhri Jeddi, Karim Aoun, Aïda Bouratbine, Elisa Cupolillo, Gerald F. Späth
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Protozoan parasites of the genus Leishmania adapt to environmental change through chromosome and gene copy number variations. Only little is known about external or intrinsic factors that govern Leishmania genomic adaptation. Here, by conduc
Externí odkaz:
https://doaj.org/article/56d904b3382f42ed88d1c4dbf455eff6
Autor:
Laura Botana, Belén Matía, Juan V. San Martin, Alberto Romero-Maté, Alicia Castro, Laura Molina, Laura Fernandez, Ana Ibarra-Meneses, Marta Aguado, Carmen Sánchez, Luis Horrillo, Carmen Chicharro, Javier Nieto, Sheila Ortega, José Manuel Ruiz-Giardin, Eugenia Carrillo, Javier Moreno
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Increased numbers of peripheral blood mononucleocytes (PBMC) and increased IFN-γ secretion following in vitro challenge of blood samples with soluble Leishmania antigen (SLA), have been proposed as biomarkers of specific cell-mediated immunity, indi
Externí odkaz:
https://doaj.org/article/00b70dde943a42c2a5164770cb9da17f
Autor:
Ignacio Hernandez, Laura Tesoro, Rafael Ramirez-Carracedo, Javier Diez-Mata, Sandra Sanchez, Marta Saura, Jose Luis Zamorano, Carlos Zaragoza, Laura Botana
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2902 (2021)
In response to cardiac ischemia/reperfusion, proteolysis mediated by extracellular matrix metalloproteinase inducer (EMMPRIN) and its secreted ligand cyclophilin-A (CyPA) significantly contributes to cardiac injury and necrosis. Here, we aimed to inv
Externí odkaz:
https://doaj.org/article/ce40e274efd4462bac27bab3cf96c9df
Autor:
Rafael Ramirez-Carracedo, Laura Tesoro, Ignacio Hernandez, Javier Diez-Mata, Laura Botana, Marta Saura, Marcelo Sanmartin, Jose Luis Zamorano, Carlos Zaragoza
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6566 (2020)
Ivabradine can reduce heart rate through inhibition of the current I(f) by still unexplored mechanisms. In a porcine model of ischemia reperfusion (IR), we found that treatment with 0.3 mg/kg Ivabradine increased plasma release of microvesicles (MVs)
Externí odkaz:
https://doaj.org/article/f91d74818f4c4ccdbc68fb10d9651645
Autor:
Laura Tesoro, Laura Botana, Ignacio Hernandez Navarro, Rafael Ramirez-Carracedo, Jose L Zamorano, Marta Saura, Carlos Zaragoza
Publikováno v:
Circulation Research. 131
Introduction: Interleukin-10 (IL-10) has long been recognized as a key anti-inflammatory cytokine, whose expression is associated to macrophage polarization towards resolution after acute myocardial infarction. Hypothesis: Targeting the IL10 receptor
Autor:
Laura Tesoro, Laura Botana, Rafael Ramírez-Carracedo, Ignacio Hernández, Javier Díez-Mata, Nunzio Alcharani, Marta Saura, Beatriz Jiménez-Guirado, Karina Ovejero-Paredes, Marco Filice, Jose Luis Zamorano, Carlos Zaragoza
Rationale: Early response after acute myocardial infarction (AMI) is crucial to prevent extensive cardiac necrosis. Interleukin-10 (IL-10) is a key antiinflammatory cytokine, whose expression is closely associated with macrophage polarization towards
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647012bdadea1b4d4715a5c50bf55bd0
https://doi.org/10.21203/rs.3.rs-1228158/v1
https://doi.org/10.21203/rs.3.rs-1228158/v1