Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Laura Bortolin"'
Autor:
Chelsea Lennartz, Joel Kurucar, Stephen Coppola, Janice Crager, Johanna Bobrow, Laura Bortolin, James Comolli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Information obtained from the analysis of dust, particularly biological particles such as pollen, plant parts, and fungal spores, has great utility in forensic geolocation. As an alternative to manual microscopic analysis of dust components,
Externí odkaz:
https://doaj.org/article/69aeba7e27b64fb7904788a09ce101dc
Autor:
Alyssa Lutservitz, James Nemesh, Gord Fishell, Alec Wysoker, Benjamin Schuman, Steven A. McCarroll, Kirsten Levandowski, Marta Florio, Victor Tkachev, David Kulp, Richard S. Smith, Arpiar Saunders, Nora Reed, Elizabeth Bien, Monika Burns, Laura Bortolin, Leslie S. Kean, Carolyn Wu, Melissa Goldman, Qiangge Zhang, Christopher A. Walsh, Bernardo Rudy, Heather Zaniewski, Ricardo C.H. del Rosario, Fenna M. Krienen, Robert Machold, Christopher D. Mullally, Guoping Feng, Jessica Lin, Jordane Dimidschstein, Marian Fernandez-Otero, Sabina Berretta
Publikováno v:
Nature
Primates and rodents, which descended from a common ancestor around 90 million years ago1, exhibit profound differences in behaviour and cognitive capacity; the cellular basis for these differences is unknown. Here we use single-nucleus RNA sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6400b2efc5b2854f6fa29814f775c31
https://doi.org/10.1038/s41586-020-2781-z
https://doi.org/10.1038/s41586-020-2781-z
Autor:
Steven A. McCarroll, Brian J. Joseph, Inma Cobos, Laura Bortolin, Irena Kadiu, Sulagna Ghosh, Alexander Couto, Aaron Burberry, Daniel Meyer, Kevin Eggan, Olli Pietilainen, Melissa Goldman, Francesco Limone, Beth Stevens, Martine Therrien, Daniel A. Mordes
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder characterised by a progressive loss of motor function. The eponymous spinal sclerosis observed at autopsy is the result of the degeneration of extratelencephalic neurons, Betz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8831769520c89a3efdd9b877e0f309d6
https://doi.org/10.1101/2021.07.12.452054
https://doi.org/10.1101/2021.07.12.452054
Autor:
Laura Bortolin, Daniel P. Salem, Jonian Grosha, Ibukunoluwapo O. Zabroski, Sanchari Banerjee, Daniel Gusenleitner, Kelly M. Biette, Christopher R. Sedlak, Anthony D. Couvillon, Peter A. Duff, Delaney M. Byrne, MacKenzie Sadie King, Amy Jamieson, Emily S. Winn-Deen, Jessica N. McAlpine, David Huntsman, Steven Skates, Eric K. Huang, Joseph Charles Sedlak
Publikováno v:
Journal of Clinical Oncology. 40:5542-5542
5542 Background: Detection of cancer with improved discrimination compared to current blood tests could be achieved using an approach that assesses extracellular vesicles (EVs). This approach should have high sensitivity (se) because of EVs abundance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6150979f0e6561efd01fdfee45ceb545
https://doi.org/10.1200/jco.2022.40.16_suppl.5542
https://doi.org/10.1200/jco.2022.40.16_suppl.5542
Autor:
Marcelo Daniel Boer, Laura Bortolin
Publikováno v:
Evidencia. Actualización en la Práctica Ambulatoria, Vol 10, Iss 2 (2007)
Externí odkaz:
https://doaj.org/article/140e78466b8c49a3a33f847a667eda4f
Autor:
Gord Fishell, Christopher A. Walsh, Heather Zaniewski, Benjamin Schuman, Marian Fernandez-Otero, Monika Burns, Nora Reed, Carolyn Wu, Guoping Feng, Leslie S. Kean, Victor Tkachev, Steven A. McCarroll, Kirsten Levandowski, Alec Wysoker, Alyssa Lutservitz, Jordane Dimidschstein, Melissa Goldman, Marta Florio, Jessica Lin, James Nemesh, David Kulp, Robert Machold, Arpiar Saunders, Richard S. Smith, Christopher D. Mullally, Bernardo Rudy, Elizabeth Bien, Qiangge Zhang, Laura Bortolin, Sabina Berretta, Ricardo C.H. del Rosario, Fenna M. Krienen
Primates and rodents, which descended from a common ancestor more than 90 million years ago, exhibit profound differences in behavior and cognitive capacity. Modifications, specializations, and innovations to brain cell types may have occurred along
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1720d420faca29ebefa66a2db17a993
This protocol enables rapid isolation of intact nuclei from brain tissue, including highly myelinated adult brain tissue. We have used it successfully to extract nuclei for single-nucleus RNA-seq from human, mouse, marmoset, and macaque brain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd76ba6aaaf3cc59ca2f23230bd455b0
https://doi.org/10.17504/protocols.io.2srged6
https://doi.org/10.17504/protocols.io.2srged6
Autor:
Arpiar Saunders, Monika Burns, Christopher A. Walsh, Marta Florio, David Kulp, Robert Machold, Nora Reed, Marian Fernandez-Otero, Carolyn Wu, Christopher D. Mullally, Alec Wysoker, Heather Zaniewski, Elizabeth Bien, Melissa Goldman, Ricardo C.H. del Rosario, Benjamin Schuman, Fenna M. Krienen, Bernardo Rudy, Leslie S. Kean, Gord Fishell, James Nemesh, Laura Bortolin, Jessica Lin, Richard S. Smith, Jordane Dimidschstein, Sabina Berretta, Victor Tkachev, Guoping Feng, Alyssa Lutservitz, Steven A. McCarroll, Kirsten Levandowski, Qiangge Zhang
Publikováno v:
Nature. 588:E17-E17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10916fe9dd584ed60514480a6345f2e3
https://doi.org/10.1038/s41586-020-2874-8
https://doi.org/10.1038/s41586-020-2874-8
Autor:
Steven A. McCarroll, Aleksandrina Goeva, Laura Bortolin, Melissa Goldman, Fenna M. Krienen, Shuyu Wang, David Kulp, Sara A. Brumbaugh, Alec Wysoker, Heather de Rivera, Nolan Kamitaki, Arpiar Saunders, Evan Z. Macosko, Matthew A. Baum, James Nemesh, Elizabeth Bien
The mammalian brain is composed of diverse, specialized cell populations. To systematically ascertain and learn from these cellular specializations, we used Drop-seq to profile RNA expression in 690,000 individual cells, sampled from nine regions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91e00ddf4eb6143a0f14bdcfe5b124d
https://europepmc.org/articles/PMC6447408/
https://europepmc.org/articles/PMC6447408/
Autor:
Steven A. McCarroll, Alec Wysoker, Laura Bortolin, Evan Z. Macosko, Arpiar Saunders, James Nemesh, Melissa Goldman
Publikováno v:
Schizophrenia Bulletin. 43:S61-S61
Background: Brain circuitry can undergo profound changes in connectivity and function without overt, microscopically visible changes in anatomy or structure. The goal of this work is to better understand, at a molecular level, periods in development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b265bdba53fc58dcf9970eb14914dc8
https://doi.org/10.1093/schbul/sbx021.160
https://doi.org/10.1093/schbul/sbx021.160