Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Laura Borsi"'
Autor:
Elisa Ventura, Francesca Sassi, Arianna Parodi, Enrica Balza, Laura Borsi, Patrizia Castellani, Barbara Carnemolla, Luciano Zardi
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9145 (2010)
BACKGROUND: Fibronectin (FN) is a multi-domain molecule involved in many cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion. The biological activities of FN are mediated by exposed loops located ma
Externí odkaz:
https://doaj.org/article/4c9ee2a2a5674c5ab0fa1da74783e926
Autor:
Alberto Amadori, Stefano Indraccolo, Ermanno Ancona, Alberto Ruol, Enrica Balza, Laura Borsi, Elisabetta Zulato, Giovanni Esposito, Luca Persano, Marika Crescenzi
Purpose: Targeting the tumor vasculature by vascular disrupting agents (VDAs) has shown therapeutic activity in mouse models. In most cases, however, VDA efficacy is substantially compromised by the inability of these drugs to completely kill tumor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa12124f0410308d8ab35f58221220e
https://doi.org/10.1158/1078-0432.c.6519840.v1
https://doi.org/10.1158/1078-0432.c.6519840.v1
Autor:
Cannata Massimiliano, Neumann Jakob, Cardoso Mirko, Rossetto Rudy, Foglia Laura, Borsi Iacopo
The MODFLOW Lake Package is integrated into the FREEWAT GIS environment in order to simulate surface water - groundwater interaction using state of the art techniques for numerical simulations, thus allowing the improved consideration of surface wate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6695befc6847012823a10d78bf858f83
The main expected impacts of FREEWAT are to help produce scientifically and technically sound decisions and policy making based on innovative data analysis tools and to support a participatory approach through all phases of a project, from scenario g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c037980f615227cadf39d6c00067180
FREEWAT main result is an open source and public domain GIS integrated modelling environment (the FREEWAT platform) for the simulation of water quantity and quality in surface water and groundwater with an integrated water management and planning mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::288b5616465098ecb26b4ec3172d39eb
Autor:
Paola Orecchia, Patrizia Castellani, Barbara Carnemolla, Enrica Balza, Lorenzo Mortara, Laura Borsi
Publikováno v:
Cancer Medicine
L19-tumor necrosis factor alpha (L19mTNF-α; L), a fusion protein consisting of mouse TNFα and the human antibody fragment L19 directed to the extra domain-B (ED-B) of fibronectin, is able to selectively target tumor vasculature and to exert a long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109f694b438e4fd7bb1be370256780f0
https://doi.org/10.1002/cam4.89
https://doi.org/10.1002/cam4.89
Autor:
Alberto Ruol, Stefano Indraccolo, Elisabetta Zulato, Ermanno Ancona, Laura Borsi, Luca Persano, Giovanni Esposito, Marika Crescenzi, Enrica Balza, Alberto Amadori
Publikováno v:
Clinical Cancer Research. 17:447-458
Purpose: Targeting the tumor vasculature by vascular disrupting agents (VDAs) has shown therapeutic activity in mouse models. In most cases, however, VDA efficacy is substantially compromised by the inability of these drugs to completely kill tumor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3647180112c2d4d31da609b104b665
https://doi.org/10.1158/1078-0432.ccr-10-1420
https://doi.org/10.1158/1078-0432.ccr-10-1420
Autor:
E. Stronen, J. Walia, Patrizia Castellani, X. Liu, A. Facciabene, K. J. Adams, X. Shang, L. Wu, Y. Zhang, T. Sugiyama, T. Felizardo, S. Wälchli, M. Toebes, S. Schmucker, J. Johansen, S. E. Church, T. Nishimura, T. Waks, N. Liddy, A. Marcus, Roberto S. Accolla, N. J. Pumphrey, J. A. Medin, M. Schmück, A. Mackiewicz, M. Kagabu, A. Richter, T. M. Mahon, Y. Wu, V. Salerno, H. Ikeda, K. M. Friedman, A. Fischer, L. Fallang, T. Takeshima, A. Labbe, E. Aleksaite, E. Morris, M. Yamane, A. Vuidepot, A. Römhild, Xue-Feng Bai, K. Takeda, A. Gedvilaite, N. M. Lissin, Barbara Carnemolla, S. M. Jensen, D. W. Kowalczyk, Laura Borsi, H. van den Poel, Lorenzo Mortara, C. J. Shu, D. Wakita, Y. Li, B. K. Jakobsen, N. Liu, K. Chamoto, F. Lund-Johansen, Y. Maekawa, John P. Hagan, K. Oosterhuis, K. Yasutomo, Y. Cai, N. J. Hassan, J. Olweus, I. Tawara, G. Brestrich, Hani Y. El-Omrani, C. J. Paige, U. Blohm, T. Ohkuri, Pramod S. Joshi, Y. Chu, I. C. Chua, C. B. Bifulco, Z. Rose, D. Xu, G. Coukos, C. Linnemann, H. Shirato, B. A. Fox, H. Shiku, E. P. Kwiatkowska, I. Weum Abrahamsen, S. Hans, A. Holler, D. D. Williams, R. Ashfield, K. Mori, H. Volk, J. Gavarret, Z. Eshhar, F. Luo, L. Wang, D. Soncini, C. Furlonger, P. Reinke, P. E. Molloy, H. Kitamura, M. E. Nelles, G. M. Bendle, Enrica Balza, C. Liu, S. Kumari, N. Imai, Y. Xiao, R. Hoppes, H. Ovaa, U. O. Kazimierczak, S. Luu, A. Kaiser, A. K. Sewell, G. Bossi, T. N. M. Schumacher, Jin-Qing Liu
Publikováno v:
International Immunology. 22:i173-i177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8a7f66528b40014ce51388e63723d6e
https://doi.org/10.1093/intimm/dxq141
https://doi.org/10.1093/intimm/dxq141
Autor:
Dario Neri, Hartwig Kosmehl, Robert Köllner, Raffaella Giavazzi, Laura Borsi, Astrid Voigt, Marcus Franz, Angela Berndt, Petra Richter, Alexander Berndt
Publikováno v:
Histochemistry and Cell Biology; Vol 133
Tumour angioneogenesis is associated with the reexpression of oncofetal fibronectin (oncFn) and tenascin-C (oncTn-C) splice variants, which may serve as targets for antibody-based pharmacodelivery. Knowledge of the vascular distribution and organizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b03439eed04fbabecbd509375edaf9
Autor:
Patrizia Castellani, Lorenzo Mortara, Barbara Carnemolla, Roberto S. Accolla, Laura Borsi, Debora Soncini, Enrica Balza
Publikováno v:
International Journal of Cancer. 127:101-110
L19-IL2 and L19TNFalpha are fusion proteins composed of L19(scFv), specific for the angiogenesis-associated ED-B containing fibronectin isoform and IL-2 or TNFalpha. Because of the tumor targeting properties of L19, IL-2 and TNFalpha concentrate at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39397a9cc7e5530229126b3f15e07bb1
https://doi.org/10.1002/ijc.25018
https://doi.org/10.1002/ijc.25018