Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Laura Bonati"'
Autor:
Stefano Motta, Laura Bonati
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9339 (2023)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the biological and toxicological effects of structurally diverse chemicals, including halogenated aromatic hydrocarbons. In this work, we investigate the eff
Externí odkaz:
https://doaj.org/article/d4e7670362e84829850185aed5e07345
Autor:
Vanessa Brinkmann, Margherita Romeo, Lucie Larigot, Anne Hemmers, Lisa Tschage, Jennifer Kleinjohann, Alfonso Schiavi, Swantje Steinwachs, Charlotte Esser, Ralph Menzel, Sara Giani Tagliabue, Laura Bonati, Fiona Cox, Niloofar Ale-Agha, Philipp Jakobs, Joachim Altschmied, Judith Haendeler, Xavier Coumoul, Natascia Ventura
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 613 (2022)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor whose activity can be modulated by polyphenols, such as curcumin. AhR and curcumin have evolutionarily conserved effects on aging. Here, we investigated whether and how th
Externí odkaz:
https://doaj.org/article/fae757d48604452eaa2ef9ce87487b2d
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4111 (2020)
1,2-naphthoquinone (1,2-NQ) and 1,4-naphthoquinone (1,4-NQ) are clinically promising biologically active chemicals that have been shown to stimulate the aryl hydrocarbon receptor (AhR) signaling pathway, but whether they are direct or indirect ligand
Externí odkaz:
https://doaj.org/article/1466aba4fb2a437c9e83bc95b78d5784
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2474 (2020)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the biological and toxicological effects of an AhR lacking the entire PASB structurally diverse chemicals, including halogenated aromatic hydrocarbons. Ligan
Externí odkaz:
https://doaj.org/article/5a02f679d2334e5187a704d115a8ad5d
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 2, p e1006021 (2018)
Hypoxia inducible factors (HIFs) are transcription factors belonging to the basic helix-loop-helix PER-ARNT-SIM (bHLH-PAS) protein family with a role in sensing oxygen levels in the cell. Under hypoxia, the HIF-α degradation pathway is blocked and d
Externí odkaz:
https://doaj.org/article/dd6ca600a16f47e5a611e961c347abc8
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 130, Iss Proc. Wivace 2013, Pp 83-86 (2013)
An approach that combines Self-Organizing maps, hierarchical clustering and network components is presented, aimed at comparing protein conformational ensembles obtained from multiple Molecular Dynamic simulations. As a first result the original ense
Externí odkaz:
https://doaj.org/article/142b7de30cf84d1185a06564b1a2b567
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 6, p e1004981 (2016)
The Aryl hydrocarbon Receptor (AhR) is a transcription factor that mediates the biochemical response to xenobiotics and the toxic effects of a number of environmental contaminants, including dioxins. Recently, endogenous regulatory roles for the AhR
Externí odkaz:
https://doaj.org/article/503c86348a8940ff9e0941c4c847f104
Autor:
Samantha C. Faber, Anatoly A. Soshilov, Sara Giani Tagliabue, Laura Bonati, Michael S. Denison
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2692 (2018)
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that modulates gene expression following its binding and activation by structurally diverse chemicals. Species differences in AhR functionality have been observed, with th
Externí odkaz:
https://doaj.org/article/036cd3b1e1b546338192bbbb5c895fe9
Autor:
Qin Hu, Guochun He, Jing Zhao, Anatoly Soshilov, Michael S Denison, Aiqian Zhang, Huijun Yin, Domenico Fraccalvieri, Laura Bonati, Qunhui Xie, Bin Zhao
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66258 (2013)
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates many of the biological and toxicological actions of structurally diverse chemicals. In this study, we examined the ability of a series of ginsenosides extrac
Externí odkaz:
https://doaj.org/article/c129c5c557bd40f5ab8073812b5b5252
Autor:
Stefano Motta, Paulo Siani, Edoardo Donadoni, Giulia Frigerio, Laura Bonati, Cristiana Di Valentin
Inorganic nanoparticles show promising properties that allow them to be efficiently used as drug carriers. The main limitation in this type of application is currently the drug loading capacity, which can be overcome with a proper functionalization o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5332781aae0cf74c97f2a14456f07483
https://hdl.handle.net/10281/420665
https://hdl.handle.net/10281/420665