Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Laura Bonapace"'
Autor:
Federica Zilli, Pedro Marques Ramos, Priska Auf der Maur, Charly Jehanno, Atul Sethi, Marie‐May Coissieux, Tobias Eichlisberger, Loïc Sauteur, Adelin Rouchon, Laura Bonapace, Joana Pinto Couto, Roland Rad, Michael Rugaard Jensen, Andrea Banfi, Michael B Stadler, Mohamed Bentires‐Alj
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
Abstract Metastasis is the main cause of deaths related to solid cancers. Active transcriptional programmes are known to regulate the metastatic cascade but the molecular determinants of metastatic colonization remain elusive. Using an inducible pigg
Externí odkaz:
https://doaj.org/article/42ad8c50455f42c9bfe8d2e92e8ddc15
Autor:
Laura Bonapace, Matthias Rössle, Kirsten D. Mertz, Silvia Dehler, Melanie Sachs, Martina Storz, Gerhard F. Huber, Tobias Junt, Gieri Cathomas, Holger Moch
Publikováno v:
International Journal of Surgical Pathology. 24:394-400
The cytokine interleukin-33 (IL-33) is abundantly expressed in epithelial barrier tissues such as salivary glands. Here, we characterized nuclear IL-33 protein expression by immunohistochemistry in benign and malignant salivary gland tumors and assoc
Autor:
Jeffrey Wyckoff, Mohamed Bentires-Alj, Bérengère Fayard, Marie-May Coissieux, Gwen MacDonald, Shunya Kondo, Hilmar Ebersbach, Arno Doelemeyer, Laura Bonapace, Marinus R. Heideman, Nancy E. Hynes, Tatiana Smirnova
Publikováno v:
Impact Journals
Oncotarget
Oncotarget
The extracellular serine protease inhibitor serpinE2 is overexpressed in breast cancer and has been shown to foster metastatic spread. Here, we investigated the hypothesis that serpinE2 creates tumor-promoting conditions in the tumor microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b7c6b494b711d9b4dcb10c51d8d625
http://hdl.handle.net/1721.1/107692
http://hdl.handle.net/1721.1/107692
Autor:
Tobias Junt, Mohamed Bentires-Alj, Jeffrey Wyckoff, Thomas G. Oertner, Laura Bonapace, Jacco van Rheenen
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia, 17(2), 125-129. Springer New York
A fundamental hallmark of cancer is progression to metastasis and the growth of breast cancer metastases in lung, bone, liver and/or brain causes fatal complications. Unfortunately, the cellular and biochemical mechanisms of the metastatic process re
Autor:
Maike Schmitz, Laura Bonapace, Jean-Pierre Bourquin, Urs Ziegler, Beat Bornhauser, Martin Schrappe, Beat W. Schäfer, Martin Stanulla, Felix Niggli, Gunnar Cario
Publikováno v:
Journal of Clinical Investigation. 120:1310-1323
In vivo resistance to first-line chemotherapy, including to glucocorticoids, is a strong predictor of poor outcome in children with acute lymphoblastic leukemia (ALL). Modulation of cell death regulators represents an attractive strategy for subverti
Autor:
Jeffrey Wyckoff, Tobias Junt, Marie-May Coissieux, Zsuzsanna Varga, Kirsten D. Mertz, Mohamed Bentires-Alj, Laura Bonapace
Publikováno v:
Nature
Secretion of C-C chemokine ligand 2 (CCL2) by mammary tumours recruits CCR2-expressing inflammatory monocytes to primary tumours and metastatic sites, and CCL2 neutralization in mice inhibits metastasis by retaining monocytes in the bone marrow. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68126932a04b0977f1f2d2ecdd16019a
https://www.zora.uzh.ch/id/eprint/99899/
https://www.zora.uzh.ch/id/eprint/99899/
Autor:
Martin Stanulla, Beat Bornhauser, Felix Niggli, Martin Schrappe, Barbara Meissner, Gunnar Cario, André Schrauder, Petra Breithaupt, Laura Bonapace, Jean-Pierre Bourquin, Maike Schmitz, Nastassja Scheidegger, Paulina Mirkowska, Joelle Tchinda
Publikováno v:
Blood
Clonal evolution of the leukemogenic compartment may contribute to alter the therapeutic response in acute lymphoblastic leukemia (ALL). Using xenotransplantation of primary leukemia cells, we evaluated the phenotypic and genetic composition of de no
Autor:
Felix K. Niggli, Rodrigo Martinez, Martin Schrappe, Dan Lindholm, Laura Bonapace, Gunnar Cario, Jean-Pierre Bourquin, Beat Bornhauser, Beat W. Schäfer
Publikováno v:
Blood. 110(6)
Incorporation of apoptosis-inducing agents into current therapeutic regimens is an attractive strategy to improve treatment for drug-resistant leukemia. We tested the potential of arsenic trioxide (ATO) to restore the response to dexamethasone in glu
Autor:
Beat Bornhauser, Martin Stanulla, Gunnar Cario, Paulina Mirkowska, Laura Bonapace, Maike Schmitz, André Schrauder, B Meissner, Martin Schrappe, Joelle Tchinda, Petra Breithaupt, Bourquin Jean-Pierre, Nastassja Scheidegger
Publikováno v:
Cancer Research. 71:5330-5330
Xenotransplantation of primary leukemia cells constitutes an attractive strategy to model disease for translational research, but the consequences of selective pressure on leukemia cells need to be clarified. Here we evaluate the phenotypic and genet
Autor:
Beat Bornhauser, Laura Bonapace, Felix Niggli, Martin Schrappe, Gunnar Cario, Jean-Pierre Bourquin, Beat W. Schaefer
Publikováno v:
Blood. 110:806-806
Incorporation of cell death-inducing agents into current therapeutic regimens is an attractive strategy to improve treatment for drug resistant leukemia. We tested the potential of the pan-Bcl-2 family antagonist BH3 mimetic obatoclax (GX15-070) to r