Výsledky vyhledávání

A route to potent, selective and biased salvinorin chemical space

Autor: Sarah Hill, Nathan Dao, Vuong Dang, Edward Stahl, Laura Bohn, Ryan Shenvi

The salvinorins serve as templates for next generation analgesics, antipruritics and dissociative hallucinogens via selective and potent agonism of the kappa-opioid receptor (KOR). In contrast to most opioids, the salvinorins lack basic amines and bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8df311cadb9adea70435f34cba9fcbf9
https://doi.org/10.26434/chemrxiv-2023-h7h38

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Migration und Gegenwartsliteratur: Der Beitrag von Autorinnen und Autoren osteuropäischer Herkunft zur literarischen Kultur im deutschsprachigen Raum. Ed. Matthias Aumüller and Weertje Willms. Paderborn, Gemany: Brill / Wilhelm Fink Verlag, 2020. xx, 248 pp. Notes. Bibliography. Illustrations. €149.00, hard bound

Autor: Laura Bohn Case

Publikováno v: Slavic Review. 81:502-504

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45d03346014a5e1eb54a10301758bc3f
https://doi.org/10.1017/slr.2022.179

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Reasons for Dropping Out of a Stress Reduction Program Based on Acceptance and Commitment Therapy for College Students

Autor: Renata Klein Zancan, Laura Bohn Constantinopolos, Bárbara Etchegaray Pankowski, Margareth Da Silva Oliveira

Publikováno v: Contextos Clínicos; v. 15 n. 1 (2022): Jan-Abr
Contextos Clínicos
Universidade do Vale do Rio dos Sinos (UNISINOS)
instacron:Unisinos

Estudos tem mostrado um aumento nos níveis de estresse e outras psicopatologias em universitários. Porém, a busca por ajuda e a adesão a programas ou serviços de saúde mental nas universidades ainda é menor que a demanda. O objetivo deste estu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94f7e97acd031899d5c0d73002a7399
https://revistas.unisinos.br/index.php/contextosclinicos/article/view/23646

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Functional analysis of key residues involved in CB1 and CB2 activation

Autor: Christina A. Brust, Jo‐Hao Ho, Edward Stahl, Christos Iliopoulos‐Tsoutsouvas, Spyros Nikas, Alexandros Makriyannis, Laura Bohn

Publikováno v: The FASEB Journal. 36

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2bdab2753d3cb680a41cef0b22da2b6
https://doi.org/10.1096/fasebj.2022.36.s1.0r791

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Asymmetric syntheses of (+)- and (–)-collybolide enable reevaluation of kappa-opioid receptor agonism

Autor: Sophia Shevick, Stephan Freeman, Guanghu Tong, Robin Russo, Laura Bohn, Ryan Shenvi

The fungal metabolite collybolide attracted attention as a non-nitrogenous, potent and biased agonist of the kappa-opioid receptor (KOR). Here we report a 10-step asymmetric synthesis of this complex sesquiterpene that enables facile access to either

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f8654f00b46d11b7a787a97e2487b3
https://doi.org/10.26434/chemrxiv-2021-rtxqf

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‘ICH BIN GENAUSO DEUTSCH WIE KAFKA’: GERMAN LINGUISTIC IDENTITY IN THE NOVELS OF TERÉZIA MORA

Autor: Laura Bohn Case

Publikováno v: German Life and Letters. 68:211-227

Terezia Mora, the translingual author of Alle Tage, Der einzige Mann auf dem Kontinent and Das Ungeheuer, demands an unqualified place within German literature, claiming ‘Ich bin genauso deutsch wie Kafka’. With Kafka, Mora chooses an author who

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f1da7dc64d946ab67afeb6107faa275
https://doi.org/10.1111/glal.12077

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10-step Synthesis of 20-nor-Salvinorin A by Dynamic Strategic Bond Analysis

Autor: Jeremy Roach, Yusuke Sasano, Cullen Schmid, Saheem Zaidi, Vsevolod Katritch, Raymond Stevens, Laura Bohn, Ryan Shenvi

Salvinorin A (SalA) is a plant metabolite that agonizes the human kappa-opioid receptor (κ-OR) with high affinity and high selectivity over mu- and delta-opioid receptors. Its therapeutic potential has stimulated extensive semi-synthetic studies and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17bf3dde3baf5e75d248b548d73c1ce0
https://doi.org/10.26434/chemrxiv.5318188

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Aaptamine and related products. Their isolation, chemical syntheses, and biological activity

Autor: Maria Laura Bohn, Enrique L. Larghi, Teodoro S. Kaufman

Publikováno v: Tetrahedron. 65:4257-4282

Fil: Larghi, Enrique Leandro. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Rosario. Instituto de Quimica Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquimicas y Farmaceuticas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d898d0041638423b9a748c8ac7c2526
https://doi.org/10.1016/j.tet.2009.03.027

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