Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Laura Bierhansl"'
Autor:
Kai Siebenbrodt, Laurent M. Willems, Felix von Podewils, Peter Michael Mross, Michael Strüber, Lisa Langenbruch, Laura Bierhansl, Iris Gorny, Juliane Schulz, Bernadette Gaida, Nadine Conradi, Annika Süß, Felix Rosenow, Adam Strzelczyk
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-10 (2023)
Abstract Background Assessment of quality of life (QoL) has become an important indicator for chronic neurological diseases. While these conditions often limit personal independence and autonomy, they are also associated with treatment-related proble
Externí odkaz:
https://doaj.org/article/acda02d20413496b902a0e724f531633
Autor:
Laura Bierhansl, Tobias Ruck, Steffen Pfeuffer, Catharina C. Gross, Heinz Wiendl, Sven G. Meuth
Publikováno v:
Neurological Research and Practice, Vol 1, Iss 1, Pp 1-9 (2019)
Abstract Background Multiple sclerosis is one of the most prevalent neurological diseases in young adults affecting over 2 million people worldwide. Alemtuzumab is a highly effective therapy in relapsing remitting MS. Alemtuzumab is a monoclonal CD52
Externí odkaz:
https://doaj.org/article/e78016dfa2d94a6e975363a327e31c7b
Autor:
Lukas Gola, Laura Bierhansl, Nicolas Hummel, Lisanne Korn, Matthias Pawlowski, Manuela Cerina, Petra Hundehege, Thomas Budde, Simone König, Sven G. Meuth, Heinz Wiendl, Stjepana Kovac
Publikováno v:
Free Radical Biology and Medicine. 194:337-346
Hyperexcitability-induced neuronal damage plays a role both in epilepsy as well as in inflammatory brain diseases such as multiple sclerosis (MS) and as such represents an important disease pathway which potentially can be targeted to mitigate neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcec4e2f092e5c81d185ca2b95f74f2c
https://doi.org/10.1016/j.freeradbiomed.2022.12.010
https://doi.org/10.1016/j.freeradbiomed.2022.12.010
Publikováno v:
Nature Reviews Drug Discovery. 21:578-600
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that causes demyelination, axonal degeneration and astrogliosis, resulting in progressive neurological disability. Fuelled by an evolving understanding of MS immunopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7ebfbce8b0493fc80857be9048553f
https://doi.org/10.1038/s41573-022-00477-5
https://doi.org/10.1038/s41573-022-00477-5
Autor:
Lukas Gola, Laura Bierhansl, Júlia Csatári, Christina B. Schroeter, Lisanne Korn, Venu Narayanan, Manuela Cerina, Sara Abdolahi, Anna Speicher, Alexander M. Hermann, Simone König, Albena T. Dinkova-Kostova, Tawfeeq Shekh-Ahmad, Sven G. Meuth, Heinz Wiendl, Ali Gorji, Matthias Pawlowski, Stjepana Kovac
Publikováno v:
Cellular and Molecular Life Sciences. 80
Hyperexcitability is associated with neuronal dysfunction, cellular death, and consequently neurodegeneration. Redox disbalance can contribute to hyperexcitation and increased reactive oxygen species (ROS) levels are observed in various neurological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::264836e9f65b62ae2b073d24ad136817
https://doi.org/10.1007/s00018-023-04758-z
https://doi.org/10.1007/s00018-023-04758-z
Autor:
Catrin Mann, Edna Zinger, Bettina Schmitz, Theodor May, Felix Rosenow, Margarete Pfäfflin, Juliane Schulz, Katja Menzler, Lisa Langenbruch, Laura Bierhansl, Susanne Knake, Mario Hamacher, Annika Süß, Felix von Podewils, Susanne Schubert-Bast, Adam Strzelczyk
OBJECTIVE: Epilepsy is a chronic condition that can affect patients of all ages. Women with epilepsy (WWE) require access to specific counseling and information regarding issues related to contraception, pregnancy, and hormonal effects on seizure con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af098521e28144eeb0613e9a49505e4
https://doi.org/10.1016/j.seizure.2022.06.004
https://doi.org/10.1016/j.seizure.2022.06.004
Autor:
Catrin Mann, Annika Süß, Felix von Podewils, Felix Zahnert, Lisa Langenbruch, Laura Bierhansl, Katja Menzler, Juliane Schulz, Bernadette Gaida, Felix Rosenow, Adam Strzelczyk
Publikováno v:
Epilepsy & Behavior. 129:108650
To analyze the concerns and worries about planning to have children and being a parent as a person with epilepsy and investigate gender differences in these perceptions.The Epi2020 study was a large multicenter study focusing on different healthcare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e971a7a2bd4bcb7507d3339dc2f252a
https://doi.org/10.1016/j.yebeh.2022.108650
https://doi.org/10.1016/j.yebeh.2022.108650
Autor:
Sven G. Meuth, Laura Bierhansl, Catharina C. Gross, Steffen Pfeuffer, Tobias Ruck, Heinz Wiendl
Publikováno v:
Neurological Research and Practice
Neurological Research and Practice, Vol 1, Iss 1, Pp 1-9 (2019)
Neurological Research and Practice, Vol 1, Iss 1, Pp 1-9 (2019)
Background Multiple sclerosis is one of the most prevalent neurological diseases in young adults affecting over 2 million people worldwide. Alemtuzumab is a highly effective therapy in relapsing remitting MS. Alemtuzumab is a monoclonal CD52 antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6507166a5e7b265e833cdf06f121c9
http://europepmc.org/articles/PMC7650051
http://europepmc.org/articles/PMC7650051
Autor:
Rongyuan Chen, Katrien De Bock, Federico Taverna, Elizabeth A. V. Jones, Massimiliano Mazzone, Lena-Christin Conradi, Jermaine Goveia, Rindert Missiaen, Bart Ghesquière, Peter Carmeliet, Anna Rita Cantelmo, Bernard Gallez, Bert Cruys, Mieke Dewerchin, Bernard Thienpont, Richard M Cubbon, Francisco Morales-Rodriguez, Sarah-Maria Fendt, Sandra Schoors, Ulrike Bruning, Annalisa Zecchin, Diether Lambrechts, Xavier Sagaert, Sebastian Jessberger, Xuri Li, Joanna Kalucka, Ulrike Harjes, Guy Eelen, Ilaria Elia, Kim Vriens, Gregor-Alexander Pilz, Nadine V. Conchinha, Aleksandra Brajic, Charlotte Dubois, Pauline de Zeeuw, Brian W. Wong, Samantha Scheinok, Laura Bierhansl, Lucas Treps
Publikováno v:
Cell metabolism, Vol. 28, no. 6, p. 881-894.e13 (2018)
Cell Metabolism
Cell Metabolism, 28(6), 881-894.e13. Cell Press
Cell Metabolism
Cell Metabolism, 28(6), 881-894.e13. Cell Press
Little is known about the metabolism of quiescent endothelial cells (QECs). Nonetheless, when dysfunctional, QECs contribute to multiple diseases. Previously, we demonstrated that proliferating endothelial cells (PECs) use fatty acid β-oxidation (FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d56f53f8e852ef8e7f9fbf714d7b9a3
https://eprints.whiterose.ac.uk/135199/1/CELL-METABOLISM-FAO_quiescence_accepted.pdf
https://eprints.whiterose.ac.uk/135199/1/CELL-METABOLISM-FAO_quiescence_accepted.pdf
Autor:
Ulrike Bruning, Asjad Visnagri, Katleen Brepoels, Saar Vandekeere, Hongling Huang, Laura Bierhansl, Stephen Rayport, Nadira Yuldasheva, Stefan Vinckier, Luc Schoonjans, Sabine Wyns, Bert Cruys, Jermaine Goveia, Bart Ghesquière, Joanna Kalucka, Peter Carmeliet, Guy Eelen, Mieke Dewerchin, Annalisa Zecchin, Richard M Cubbon
Endothelial cell (EC) metabolism is emerging as a regulator of angiogenesis, but the precise role of glutamine metabolism in ECs is unknown. Here, we show that depriving ECs of glutamine or inhibiting glutaminase 1 (GLS1) caused vessel sprouting defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fa18da3e38360a36ebabdb44cb2ccd
https://eprints.whiterose.ac.uk/118500/1/GLS_EMBO_(28.5.17_2a)_GE3.docx
https://eprints.whiterose.ac.uk/118500/1/GLS_EMBO_(28.5.17_2a)_GE3.docx