Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

Autor: Nour Zeaiter, Laura Belot, Valérie Cunin, Roland Abi Nahed, Malgorzata Tokarska-Schlattner, Audrey Le Gouellec, Carlo Petosa, Saadi Khochbin, Uwe Schlattner

Publikováno v: Molecular Metabolism, Vol 81, Iss , Pp 101903- (2024)

Acetyl and other acyl groups from different short-chain fatty acids (SCFA) competitively modify histones at various lysine sites. To fully understand the functional significance of such histone acylation, a key epigenetic mechanism, it is crucial to

Externí odkaz: https://doaj.org/article/2c8561dec0af4c428dbc29f8a526993d

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Autor: Jovan Nikolic, Laura Belot, Hélène Raux, Pierre Legrand, Yves Gaudin, Aurélie A. Albertini

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Glycoprotein G of vesicular stomatitis virus (VSV) enables viral entry by binding to the major VSV receptor LDL-R. Here the authors present crystal structures of G in complex with two distinct CR domains of LDL-R, identifying structural determinants

Externí odkaz: https://doaj.org/article/c655891b73d54aeb8adf1a017f3f60af

Structural and cellular biology of rhabdovirus entry

Autor: Laura, Belot, Aurélie, Albertini, Yves, Gaudin

Publikováno v: Advances in Virus Research
Advances in Virus Research, 2019, 104, pp.147--183. ⟨10.1016/bs.aivir.2019.05.003⟩

International audience; Rhabdoviruses are enveloped viruses with a negative-sense single strand RNA genome and are widespread among a great variety of organisms. In their membrane, they have a single glycoprotein (G) that mediates both virus attachme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a70ae65ec9ba8c183963d6a29ac8a3b6
https://hal.archives-ouvertes.fr/hal-02294858

Crystal structure of Mokola virus glycoprotein in its post-fusion conformation

Autor: Yves Gaudin, Malika Ouldali, Stéphane Roche, Aurélie A. Albertini, Laura Belot, Pierre Legrand

Publikováno v: PLoS pathogens
PLoS pathogens, 2020, 16 (3), pp.e1008383. ⟨10.1371/journal.ppat.1008383⟩
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2020, 16 (3), pp.e1008383. ⟨10.1371/journal.ppat.1008383⟩
PLoS Pathogens, 2020, 16 (3), pp.e1008383. ⟨10.1371/journal.ppat.1008383⟩
PLoS Pathogens, Vol 16, Iss 3, p e1008383 (2020)

Mokola virus (MOKV) belongs to the lyssavirus genus. As other genus members—including rabies virus (RABV)—it causes deadly encephalitis in mammals. MOKV entry into host cells is mediated by its transmembrane glycoprotein G. First, G binds cellula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca8998d63665b31bf6ee1bcc939a50a
https://doi.org/10.1371/journal.ppat.1008383

Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols

Autor: Anna Grandas, David Cornu, Xavier Elduque, Aubérie Parent, Jean-Pierre Le Caer, Benoît D'Autréaux, Michel B. Toledano, Laura Belot

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2014, 6, pp.5686
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

International audience; Friedreich's ataxia is a severe neurodegenerative disease caused by the decreased expression of frataxin, a mitochondrial protein that stimulates iron-sulfur (Fe-S) cluster biogenesis. In mammals, the primary steps of Fe-S clu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695b23563a52287f0d3463f50e8de828
https://hal.archives-ouvertes.fr/hal-01111365