BUB-1 and CENP-C recruit PLK-1 to control chromosome alignment and segregation during meiosis I in C. elegans oocytes

Autor: Samuel JP Taylor, Laura Bel Borja, Flavie Soubigou, Jack Houston, Dhanya K Cheerambathur, Federico Pelisch

Publikováno v: eLife, Vol 12 (2023)

Phosphorylation is a key post-translational modification that is utilised in many biological processes for the rapid and reversible regulation of protein localisation and activity. Polo-like kinase 1 (PLK-1) is essential for both mitotic and meiotic

Externí odkaz: https://doaj.org/article/ba866f58063d402a8e2da7c7ec514fc4

Author response: BUB-1 and CENP-C recruit PLK-1 to control chromosome alignment and segregation during meiosis I in C. elegans oocytes

Autor: Laura Bel Borja, Samuel JP Taylor, Flavie Soubigou, Jack Houston, Dhanya K Cheerambathur, Federico Pelisch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::875a204a13dec3b57065e7d32ab5133e
https://doi.org/10.7554/elife.84057.sa2

BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes

Autor: Samuel J P Taylor, Jacqueline Budrewicz, Federico Pelisch, Joshua N. Bembenek, Dhanya K. Cheerambathur, Flavie Soubigou, Christopher G Sorensen Turpin, Pablo Lara-Gonzalez, Conchita Fraguas Bringas, Laura Bel Borja

Publikováno v: Bel Borja, L, Soubigou, F, Taylor, S J P, Fraguas Bringas, C, Budrewicz, J, Lara-Gonzalez, P, Sorensen Turpin, C G, Bembenek, J N, Cheerambathur, D K & Pelisch, F 2020, ' BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes ', eLIFE, vol. 9, e65307 . https://doi.org/10.7554/eLife.65307
eLife, Vol 9 (2020)

Protein Phosphatase 2A (PP2A) is an heterotrimer composed of scaffolding (A), catalytic (C), and regulatory (B) subunits with various key roles during cell division. While A and C subunits form the core enzyme, the diversity generated by interchangea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776db3de6313042a145ec96bba63df30
https://hdl.handle.net/20.500.11820/35f0ef0d-185a-4f6e-b51a-a4bc07725f47

Sumoylation regulates central spindle protein dynamics during chromosome segregation in oocytes

Autor: Federico Pelisch, Laura Bel Borja, Ronald T. Hay, Ellis Jaffray

Meiotic spindles in most species lack centrosomes and the mechanisms that underlie faithful chromosome segregation in acentrosomal meiotic spindles are not well understood. In C. elegans oocytes, spindle microtubules exert a poleward force on chromos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06aa7f3842c15e5dc9dd3178eaace69

Sumoylation regulates protein dynamics during meiotic chromosome segregation in C. elegans oocytes

Autor: Ronald T. Hay, Ellis Jaffray, Federico Pelisch, Laura Bel Borja

Publikováno v: Journal of Cell Science.

Oocyte meiotic spindles in most species lack centrosomes and the mechanisms that underlie faithful chromosome segregation in acentrosomal meiotic spindles are not well understood. In C. elegans oocytes, spindle microtubules exert a poleward force on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1af9ee7cd87792400fabbe241b998d2
https://doi.org/10.1242/jcs.232330