Výsledky vyhledávání - "Laura Batlle-Morera"

Akademický článek

Nuclear localization of MTHFD2 is required for correct mitosis progression

Autor: Natalia Pardo-Lorente, Anestis Gkanogiannis, Luca Cozzuto, Antoni Gañez Zapater, Lorena Espinar, Ritobrata Ghose, Jacqueline Severino, Laura García-López, Rabia Gül Aydin, Laura Martin, Maria Victoria Neguembor, Evangelia Darai, Maria Pia Cosma, Laura Batlle-Morera, Julia Ponomarenko, Sara Sdelci

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)

Abstract Subcellular compartmentalization of metabolic enzymes establishes a unique metabolic environment that elicits specific cellular functions. Indeed, the nuclear translocation of certain metabolic enzymes is required for epigenetic regulation a

Externí odkaz: https://doaj.org/article/de1a214426154418bc0136cb8e1db229

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Akademický článek

Human Wharton’s jelly-derived mesenchymal stromal cells promote bone formation in immunodeficient mice when administered into a bone microenvironment

Autor: Raquel Cabrera-Pérez, Alexis Ràfols-Mitjans, Ángela Roig-Molina, Silvia Beltramone, Joaquim Vives, Laura Batlle-Morera

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)

Abstract Background Wharton’s Jelly (WJ) Mesenchymal Stromal Cells (MSC) have emerged as an attractive allogeneic therapy for a number of indications, except for bone-related conditions requiring new tissue formation. This may be explained by the a

Externí odkaz: https://doaj.org/article/f7f4a9c490234a9994225d30f52e38f2

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Akademický článek

The challenge of developing human 3D organoids into medicines

Autor: Joaquim Vives, Laura Batlle-Morera

Publikováno v: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-4 (2020)

Abstract The capacity of organoids to generate complex 3D structures resembling organs is revolutionizing the fields of developmental and stem cell biology. We are currently establishing the foundations for translational applications of organoids suc

Externí odkaz: https://doaj.org/article/a4db59f42e2142d4b4583f9d276dfe23

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The challenge of developing human 3D organoids into medicines

Autor: Laura Batlle-Morera, Joaquim Vives

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-4 (2020)
Stem Cell Research & Therapy

The capacity of organoids to generate complex 3D structures resembling organs is revolutionizing the fields of developmental and stem cell biology. We are currently establishing the foundations for translational applications of organoids such as drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6bef61512930fbb0473eabebb1a8bd
https://doi.org/10.1186/s13287-020-1586-1

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Endogenous CRISPR/Cas9 arrays for scalable whole-organism lineage tracing

Autor: Laura Batlle-Morera, James Sharpe, James Cotterell, Marta Vila-Cejudo

Publikováno v: Development

The past decade has seen a renewed appreciation of the central importance of cellular lineages to many questions in biology (especially organogenesis, stem cells and tumor biology). This has been driven in part by a renaissance in genetic clonal-labe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55c589525d6fcde7f283104187420b4

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A reproducible method for the isolation and expansion of ovine mesenchymal stromal cells from bone marrow for use in regenerative medicine preclinical studies

Autor: Daniel Vivas, Laura Batlle-Morera, Joaquim Vives, Roberto Vélez, Jordi Barquinero, Marta Caminal, Joan Garcia, Marius Aguirre, R.M. Rabanal

Publikováno v: Journal of Tissue Engineering and Regenerative Medicine. 11:3408-3416

The use of multipotent mesenchymal stromal cells (MSCs) as candidate medicines for treating a variety of pathologies is based on their qualities as either progenitors for the regeneration of damaged tissue or producers of a number of molecules with p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be2dec9918dfdf1e7dd075ccf3a88c1e
https://doi.org/10.1002/term.2254

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Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency

Autor: Suzanne Camus, Vlad Pekarik, Laura Batlle Morera, Iago Maceda, Sergio Menendez, Juan Carlos Izpisua Belmonte, Michael J. Edel, Adriana Sanchez, Ida Paramonov, Manuel Collado, Antonella Consiglio, Aida Herreria, Manuel Serrano, Han Li

Publikováno v: Aging Cell. 11:41-50

Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells represent a promising therapeutic tool for many diseases, including aged tissues and organs at high risk of failure. However, the intrinsic self-renewal and pluripotency of ES and iPS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d41fb036c0eefaef746a1c2ee15e176c
https://doi.org/10.1111/j.1474-9726.2011.00754.x

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Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector

Autor: Juan Carlos Izpisua Belmonte, Ignasi Rodriguez Piza, Gustavo Tiscornia, Montserrat Barragan Monasterio, Laura Batlle Morera, Núria Montserrat i Pulido, Federico Gonzalez, Rita Vassena

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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Induced pluripotent stem (iPS) cells have generated keen interest due to their potential use in regenerative medicine. They have been obtained from various cell types of both mice and humans by exogenous delivery of different combinations of Oct4 , S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6256b750324ab7aa41538fb153af5d7
https://doi.org/10.1073/pnas.0901471106

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A reproducible method for the isolation and expansion of ovine mesenchymal stromal cells from bone marrow for use in regenerative medicine preclinical studies

Autor: Marta, Caminal, Roberto, Vélez, Rosa Maria, Rabanal, Daniel, Vivas, Laura, Batlle-Morera, Màrius, Aguirre, Jordi, Barquinero, Joan, García, Joaquim, Vives

Publikováno v: Journal of tissue engineering and regenerative medicine. 11(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75caeaed343861f8a710559381c1fbeb
https://pubmed.ncbi.nlm.nih.gov/27860364

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Parameters influencing derivation of embryonic stem cells from murine embryos

Autor: Laura Batlle-Morera, Jennifer Nichols, Austin Smith

Publikováno v: Genesis (New York, N.Y. : 2000). 46(12)

The derivation of ES cells is poorly understood and varies in efficiency between different strains of mice. We have investigated potential differences between embryos of permissive and recalcitrant strains during diapause and ES cell derivation. We f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afe16b105eb416b4a0cea5d2625fcb8
https://pubmed.ncbi.nlm.nih.gov/18837461

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