Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Laura Baldino"'
Autor:
Maurizio Scaltriti, Charles M. Rudin, Neal Rosen, Elisa de Stanchina, Gary A. Ulaner, Junji Tsurutani, Ronglai Shen, John T. Poirier, Mark G. Kris, Maria E. Arcila, Pedram Razavi, Jorge S. Reis-Filho, Vicky Makker, Alan L. Ho, Darren J. Buonocore, Jason S. Lewis, David M. Hyman, Fabiola Cecchi, Anuja Bhalkikar, Wei-Li Liao, Sheeno Thyparambil, Helena A. Yu, David R. Jones, James M. Isbell, Michael Offin, Tony Ng, Paul R. Barber, Michael F. Berger, David B. Solit, Nancy U. Lin, Rachel A. Freedman, Irmina Diala, Alshad S. Lalani, Clare J. Wilhem, Gregory Weitsman, Besnik Qeriqi, Megan Little, Inna Khodos, Marissa Mattar, Chongrui Xu, Mackenzie L. Myers, Hai-Yan Tu, Sophie Shifman, Yanyan Cai, Laura Baldino, Emiliano Cocco, Sandra Misale, Flavia Michelini, Bob T. Li
Supplementary Fig 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca68ba963c9d89ca2601a9b13e440c0
https://doi.org/10.1158/2159-8290.22535620
https://doi.org/10.1158/2159-8290.22535620
Autor:
Maurizio Scaltriti, Alexander Drilon, Andrea Ventura, Chandra S. Verma, Elisa de Stanchina, Moshe Elkabets, David M. Hyman, Jaclyn F. Hechtman, Alberto Bardelli, Barry S. Taylor, Sandra Misale, Uwe Rix, Yi Liao, Sankar Jagadeeshan, Ofra Novoplansky, Michael F. Berger, Alexander N. Gorelick, Neil Vasan, Ram Kannan, Benedetta Mussolin, Sabrina Arena, Yanyan Cai, Fan Wu, Srushti Kittane, Amaia Arruabarrena-Aristorena, Eneda Toska, Laura Baldino, Amanda Kulick, Sophie Shifman, Helen H. Won, Alison M. Schram, Srinivasaraghavan Kannan, Ji Eun Lee, Emiliano Cocco
On-target resistance to next-generation TRK inhibitors in TRK fusion–positive cancers is largely uncharacterized. In patients with these tumors, we found that TRK xDFG mutations confer resistance to type I next-generation TRK inhibitors designed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807ca77bc7845326b9d1552aaed59835
https://doi.org/10.1158/2159-8290.c.6548215.v1
https://doi.org/10.1158/2159-8290.c.6548215.v1
Autor:
Maurizio Scaltriti, Charles M. Rudin, Neal Rosen, Elisa de Stanchina, Gary A. Ulaner, Junji Tsurutani, Ronglai Shen, John T. Poirier, Mark G. Kris, Maria E. Arcila, Pedram Razavi, Jorge S. Reis-Filho, Vicky Makker, Alan L. Ho, Darren J. Buonocore, Jason S. Lewis, David M. Hyman, Fabiola Cecchi, Anuja Bhalkikar, Wei-Li Liao, Sheeno Thyparambil, Helena A. Yu, David R. Jones, James M. Isbell, Michael Offin, Tony Ng, Paul R. Barber, Michael F. Berger, David B. Solit, Nancy U. Lin, Rachel A. Freedman, Irmina Diala, Alshad S. Lalani, Clare J. Wilhem, Gregory Weitsman, Besnik Qeriqi, Megan Little, Inna Khodos, Marissa Mattar, Chongrui Xu, Mackenzie L. Myers, Hai-Yan Tu, Sophie Shifman, Yanyan Cai, Laura Baldino, Emiliano Cocco, Sandra Misale, Flavia Michelini, Bob T. Li
Supplementary Fig 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc8a692cd14f0c9c16a0213065f8c31
https://doi.org/10.1158/2159-8290.22535626
https://doi.org/10.1158/2159-8290.22535626
Autor:
Maurizio Scaltriti, Alexander Drilon, Andrea Ventura, Chandra S. Verma, Elisa de Stanchina, Moshe Elkabets, David M. Hyman, Jaclyn F. Hechtman, Alberto Bardelli, Barry S. Taylor, Sandra Misale, Uwe Rix, Yi Liao, Sankar Jagadeeshan, Ofra Novoplansky, Michael F. Berger, Alexander N. Gorelick, Neil Vasan, Ram Kannan, Benedetta Mussolin, Sabrina Arena, Yanyan Cai, Fan Wu, Srushti Kittane, Amaia Arruabarrena-Aristorena, Eneda Toska, Laura Baldino, Amanda Kulick, Sophie Shifman, Helen H. Won, Alison M. Schram, Srinivasaraghavan Kannan, Ji Eun Lee, Emiliano Cocco
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509bc17855bc29dcb35a2805f934c54c
https://doi.org/10.1158/2159-8290.22536730.v1
https://doi.org/10.1158/2159-8290.22536730.v1
Autor:
Maurizio Scaltriti, Charles M. Rudin, Neal Rosen, Elisa de Stanchina, Gary A. Ulaner, Junji Tsurutani, Ronglai Shen, John T. Poirier, Mark G. Kris, Maria E. Arcila, Pedram Razavi, Jorge S. Reis-Filho, Vicky Makker, Alan L. Ho, Darren J. Buonocore, Jason S. Lewis, David M. Hyman, Fabiola Cecchi, Anuja Bhalkikar, Wei-Li Liao, Sheeno Thyparambil, Helena A. Yu, David R. Jones, James M. Isbell, Michael Offin, Tony Ng, Paul R. Barber, Michael F. Berger, David B. Solit, Nancy U. Lin, Rachel A. Freedman, Irmina Diala, Alshad S. Lalani, Clare J. Wilhem, Gregory Weitsman, Besnik Qeriqi, Megan Little, Inna Khodos, Marissa Mattar, Chongrui Xu, Mackenzie L. Myers, Hai-Yan Tu, Sophie Shifman, Yanyan Cai, Laura Baldino, Emiliano Cocco, Sandra Misale, Flavia Michelini, Bob T. Li
Amplification of and oncogenic mutations in ERBB2, the gene encoding the HER2 receptor tyrosine kinase, promote receptor hyperactivation and tumor growth. Here we demonstrate that HER2 ubiquitination and internalization, rather than its overexpressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a598d1b4eb96d17df2dea8724ae3ecf8
https://doi.org/10.1158/2159-8290.c.6547894.v1
https://doi.org/10.1158/2159-8290.c.6547894.v1
Autor:
Maurizio Scaltriti, Charles M. Rudin, Neal Rosen, Elisa de Stanchina, Gary A. Ulaner, Junji Tsurutani, Ronglai Shen, John T. Poirier, Mark G. Kris, Maria E. Arcila, Pedram Razavi, Jorge S. Reis-Filho, Vicky Makker, Alan L. Ho, Darren J. Buonocore, Jason S. Lewis, David M. Hyman, Fabiola Cecchi, Anuja Bhalkikar, Wei-Li Liao, Sheeno Thyparambil, Helena A. Yu, David R. Jones, James M. Isbell, Michael Offin, Tony Ng, Paul R. Barber, Michael F. Berger, David B. Solit, Nancy U. Lin, Rachel A. Freedman, Irmina Diala, Alshad S. Lalani, Clare J. Wilhem, Gregory Weitsman, Besnik Qeriqi, Megan Little, Inna Khodos, Marissa Mattar, Chongrui Xu, Mackenzie L. Myers, Hai-Yan Tu, Sophie Shifman, Yanyan Cai, Laura Baldino, Emiliano Cocco, Sandra Misale, Flavia Michelini, Bob T. Li
Supplementary Fig 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aff08b15e4fc271fccf53b683c9fecf
https://doi.org/10.1158/2159-8290.22535614.v1
https://doi.org/10.1158/2159-8290.22535614.v1
Autor:
Maurizio Scaltriti, Charles M. Rudin, Neal Rosen, Elisa de Stanchina, Gary A. Ulaner, Junji Tsurutani, Ronglai Shen, John T. Poirier, Mark G. Kris, Maria E. Arcila, Pedram Razavi, Jorge S. Reis-Filho, Vicky Makker, Alan L. Ho, Darren J. Buonocore, Jason S. Lewis, David M. Hyman, Fabiola Cecchi, Anuja Bhalkikar, Wei-Li Liao, Sheeno Thyparambil, Helena A. Yu, David R. Jones, James M. Isbell, Michael Offin, Tony Ng, Paul R. Barber, Michael F. Berger, David B. Solit, Nancy U. Lin, Rachel A. Freedman, Irmina Diala, Alshad S. Lalani, Clare J. Wilhem, Gregory Weitsman, Besnik Qeriqi, Megan Little, Inna Khodos, Marissa Mattar, Chongrui Xu, Mackenzie L. Myers, Hai-Yan Tu, Sophie Shifman, Yanyan Cai, Laura Baldino, Emiliano Cocco, Sandra Misale, Flavia Michelini, Bob T. Li
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a570715ac7d71f758797eb70fda7bf
https://doi.org/10.1158/2159-8290.22535608.v1
https://doi.org/10.1158/2159-8290.22535608.v1
Autor:
Maurizio Scaltriti, Charles M. Rudin, Neal Rosen, Elisa de Stanchina, Gary A. Ulaner, Junji Tsurutani, Ronglai Shen, John T. Poirier, Mark G. Kris, Maria E. Arcila, Pedram Razavi, Jorge S. Reis-Filho, Vicky Makker, Alan L. Ho, Darren J. Buonocore, Jason S. Lewis, David M. Hyman, Fabiola Cecchi, Anuja Bhalkikar, Wei-Li Liao, Sheeno Thyparambil, Helena A. Yu, David R. Jones, James M. Isbell, Michael Offin, Tony Ng, Paul R. Barber, Michael F. Berger, David B. Solit, Nancy U. Lin, Rachel A. Freedman, Irmina Diala, Alshad S. Lalani, Clare J. Wilhem, Gregory Weitsman, Besnik Qeriqi, Megan Little, Inna Khodos, Marissa Mattar, Chongrui Xu, Mackenzie L. Myers, Hai-Yan Tu, Sophie Shifman, Yanyan Cai, Laura Baldino, Emiliano Cocco, Sandra Misale, Flavia Michelini, Bob T. Li
Supplementary Fig 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be34c1b193827111ba4ed9bb0d011a7
https://doi.org/10.1158/2159-8290.22535611
https://doi.org/10.1158/2159-8290.22535611
Autor:
Maurizio Scaltriti, Charles M. Rudin, Neal Rosen, Elisa de Stanchina, Gary A. Ulaner, Junji Tsurutani, Ronglai Shen, John T. Poirier, Mark G. Kris, Maria E. Arcila, Pedram Razavi, Jorge S. Reis-Filho, Vicky Makker, Alan L. Ho, Darren J. Buonocore, Jason S. Lewis, David M. Hyman, Fabiola Cecchi, Anuja Bhalkikar, Wei-Li Liao, Sheeno Thyparambil, Helena A. Yu, David R. Jones, James M. Isbell, Michael Offin, Tony Ng, Paul R. Barber, Michael F. Berger, David B. Solit, Nancy U. Lin, Rachel A. Freedman, Irmina Diala, Alshad S. Lalani, Clare J. Wilhem, Gregory Weitsman, Besnik Qeriqi, Megan Little, Inna Khodos, Marissa Mattar, Chongrui Xu, Mackenzie L. Myers, Hai-Yan Tu, Sophie Shifman, Yanyan Cai, Laura Baldino, Emiliano Cocco, Sandra Misale, Flavia Michelini, Bob T. Li
Supplementary Fig 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386f7bffb8bf2c445b540fb3e669b3b1
https://doi.org/10.1158/2159-8290.22535617
https://doi.org/10.1158/2159-8290.22535617
Autor:
Maurizio Scaltriti, Alexander Drilon, Andrea Ventura, Chandra S. Verma, Elisa de Stanchina, Moshe Elkabets, David M. Hyman, Jaclyn F. Hechtman, Alberto Bardelli, Barry S. Taylor, Sandra Misale, Uwe Rix, Yi Liao, Sankar Jagadeeshan, Ofra Novoplansky, Michael F. Berger, Alexander N. Gorelick, Neil Vasan, Ram Kannan, Benedetta Mussolin, Sabrina Arena, Yanyan Cai, Fan Wu, Srushti Kittane, Amaia Arruabarrena-Aristorena, Eneda Toska, Laura Baldino, Amanda Kulick, Sophie Shifman, Helen H. Won, Alison M. Schram, Srinivasaraghavan Kannan, Ji Eun Lee, Emiliano Cocco
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92832fa930dda8cd6203069c5c7206c4
https://doi.org/10.1158/2159-8290.22536727.v1
https://doi.org/10.1158/2159-8290.22536727.v1