Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Laura B. Ruiz-Avila"'
Autor:
Federico M. Ruiz, Andrea Escobar-Peña, María L. López-Rodríguez, José Manuel Andreu, Mar Martín-Fontecha, Sonia Huecas, Marta Artola, Henar Vázquez-Villa, Laura B. Ruiz-Avila, Lidia Araújo-Bazán, R Fernando Martínez, Carlos Fernández-Tornero
Publikováno v:
Journal of Medicinal Chemistry
E-Prints Complutense. Archivo Institucional de la UCM
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
E-Prints Complutense. Archivo Institucional de la UCM
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
51 p.-6 fig.-1 tab.-4 schem.-1 graph. abst.
Bacterial resistance to antibiotics makes previously manageable infections again disabling and lethal, highlighting the need for new antibacterial strategies. In this regard, inhibition of the bacteria
Bacterial resistance to antibiotics makes previously manageable infections again disabling and lethal, highlighting the need for new antibacterial strategies. In this regard, inhibition of the bacteria
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Cell division protein FtsZ is the organizer of the cytokinetic ring in almost all bacteria and a target for the discovery of new antibacterial agents that are needed to counter widespread antibiotic resistance. Bacterial cytological profiling, using
Externí odkaz:
https://doaj.org/article/18a9a56db6f6485888947145383f872a
Publikováno v:
Molecular Cell
Multi-subunit SMC ATPases control chromosome superstructure and DNA topology, presumably by DNA translocation and loop extrusion. Chromosomal DNA is entrapped within the tripartite SMC/kleisin ring. Juxtaposed SMC heads (‘J heads’) or engaged SMC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821dde36826e90df715ffd5637cd675f
https://europepmc.org/articles/PMC6934413/
https://europepmc.org/articles/PMC6934413/
Autor:
Lidia Araújo-Bazán, Henar Vázquez-Villa, María A. Oliva, Sonia Huecas, María L. López-Rodríguez, José Manuel Andreu, Mar Martín-Fontecha, Laura B. Ruiz-Avila, Pablo Chacón, Marta Artola, R Fernando Martínez, Erney Ramírez-Aportela, A. Javier Martín-Galiano
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Chemical Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chemical Science, 8(2), 1525-1534
E-Prints Complutense. Archivo Institucional de la UCM
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Chemical Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chemical Science, 8(2), 1525-1534
E-Prints Complutense. Archivo Institucional de la UCM
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
9 p.-4 fig.-1 tab. Artola, M. et al.
FtsZ is a widely conserved tubulin-like GTPase that directs bacterial cell division and a new target for antibiotic discovery.This protein assembly machine cooperatively polymerizes forming single-stranded fi
FtsZ is a widely conserved tubulin-like GTPase that directs bacterial cell division and a new target for antibiotic discovery.This protein assembly machine cooperatively polymerizes forming single-stranded fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4266a79c81606ae656471ed1b5e0bd05
https://hdl.handle.net/20.500.12530/41754
https://hdl.handle.net/20.500.12530/41754
Publikováno v:
Frontiers in Microbiology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Microbiology, Vol 7 (2016)
Recercat. Dipósit de la Recerca de Catalunya
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Microbiology, Vol 7 (2016)
Recercat. Dipósit de la Recerca de Catalunya
17 p.-9 fig.
Cell division protein FtsZ is the organizer of the cytokinetic ring in almost all bacteria and a target for the discovery of new antibacterial agents that are needed to counter widespread antibiotic resistance. Bacterial cytological
Cell division protein FtsZ is the organizer of the cytokinetic ring in almost all bacteria and a target for the discovery of new antibacterial agents that are needed to counter widespread antibiotic resistance. Bacterial cytological
Autor:
Ana Poveda, Antonio Morreale, Sonia Huecas, Sonsoles Martín-Santamaría, F. Javier Cañada, José Manuel Andreu, Almudena Perona, Filipa Marcelo, Jesús Jiménez-Barbero, Laura B. Ruiz-Avila
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
FtsZ is the key protein of bacterial cell-division and target for new antibiotics. Selective inhibition of FtsZ polymerization without impairing the assembly of the eukaryotic homologue tubulin was demonstrated with C8-substituted guanine nucleotides
Autor:
Tilman Läppchen, Claudia Schaffner-Barbero, Antonio Morreale, J. Fernando Díaz, José Manuel Andreu, Sonia Huecas, Rubén Gil-Redondo, Tanneke den Blaauwen, Laura B. Ruiz-Avila
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biochemistry, 49(49), 10458-10472. American Chemical Society
Europe PubMed Central
instname
Biochemistry, 49(49), 10458-10472. American Chemical Society
Europe PubMed Central
Supporting information of this article: Table of FtsZ inhibitors (S1), tables of MM-GBSA energies (S2-S7), tables of virtual screening compounds (S8 and S9), Figures S1-S3, and PDB files with average structures from molecular dynamics, can be found f
Autor:
Oscar Llorca, Rafael Núñez-Ramírez, Sonia Huecas, Claudia Schaffner-Barbero, Dulce Alonso, María L. López-Rodríguez, Antonio J. Martin-Galiano, Laura B. Ruiz-Avila, José Manuel Andreu
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
20 p.-8 fig.-5 fig. supl.-1 tab. supl.
Cell division protein FtsZ can form single-stranded filaments with a cooperative behavior by self-switching assembly. Subsequent condensation and bending of FtsZ filaments are important for the formation an
Cell division protein FtsZ can form single-stranded filaments with a cooperative behavior by self-switching assembly. Subsequent condensation and bending of FtsZ filaments are important for the formation an
Autor:
Jesús Jiménez-Barbero, Sonia Huecas, Laura B. Ruiz-Avila, F. Javier Cañada, Almudena Perona, Filipa Marcelo, José Manuel Andreu, Antonio Morreale
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
© 2015 American Chemical Society. FtsZ is the organizer of cell division in most bacteria and a target in the quest for new antibiotics. FtsZ is a tubulin-like GTPase, in which the active site is completed at the interface with the next subunit in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb197d11d046be0f92b49f237e79bca4
http://hdl.handle.net/10261/133284
http://hdl.handle.net/10261/133284
Autor:
Mar Martín-Fontecha, María L. López-Rodríguez, Laura B. Ruiz-Avila, Marta Artola, Stephan A. Sieber, José Manuel Andreu, Albert Vergoñós, Pablo Chacón, Lidia Araújo-Bazán, Sonia Huecas, Erney Ramírez-Aportela, Matthew B. Nodwell, Henar Vázquez-Villa, Carlos Turrado, Isabel Barasoain, Annabelle Hoegl
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
© 2014 American Chemical Society. Essential cell division protein FtsZ is considered an attractive target in the search for antibacterials with novel mechanisms of action to overcome the resistance problem. FtsZ undergoes GTP-dependent assembly at m