Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laura B. Chipman"'
Autor:
Laura B Chipman, San Luc, Ian A Nicastro, Jesse J Hulahan, Delaney C Dann, Devavrat M Bodas, Amy E Pasquinelli
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011055 (2023)
MicroRNAs (miRNAs) regulate gene expression by base-pairing to target sequences in messenger RNAs (mRNAs) and recruiting factors that induce translational repression and mRNA decay. In animals, nucleotides 2-8 at the 5' end of the miRNA, called the s
Externí odkaz:
https://doaj.org/article/79fbd3969f70495db760f99d1136f56c
Autor:
Antti P Aalto, Ian A Nicastro, James P Broughton, Laura B Chipman, William P Schreiner, Jerry S Chen, Amy E Pasquinelli
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007379 (2018)
Argonaute (AGO) proteins partner with microRNAs (miRNAs) to target specific genes for post-transcriptional regulation. During larval development in Caenorhabditis elegans, Argonaute-Like Gene 1 (ALG-1) is the primary mediator of the miRNA pathway, wh
Externí odkaz:
https://doaj.org/article/ad23563c739c482fa2fcb1cd2fc9bc5c
Autor:
Amy E. Pasquinelli, Laura B. Chipman
Publikováno v:
Trends in genetics : TIG, vol 35, iss 3
MicroRNAs (miRNAs) are small RNAs that guide Argonaute (AGO) proteins to specific target messenger RNAs (mRNAs) to repress their translation and stability. Canonically, miRNA targeting is reliant on base pairing of the seed region, nucleotides (nts)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f77cf928e5e00740dab9f6bdf40a2c3
https://pubmed.ncbi.nlm.nih.gov/30638669
https://pubmed.ncbi.nlm.nih.gov/30638669
Autor:
Jerry S. Chen, William P. Schreiner, Laura B. Chipman, Ian Nicastro, James P. Broughton, Amy E. Pasquinelli, Antti P. Aalto
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 6, p e1007379 (2018)
Aalto, A P, Nicastro, I A, Broughton, J P, Chipman, L B, Schreiner, W P, Chen, J S & Pasquinelli, A E 2018, ' Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging ', PLoS Genetics, vol. 14, no. 6, e1007379 . https://doi.org/10.1371/journal.pgen.1007379
PLoS Genetics, Vol 14, Iss 6, p e1007379 (2018)
Aalto, A P, Nicastro, I A, Broughton, J P, Chipman, L B, Schreiner, W P, Chen, J S & Pasquinelli, A E 2018, ' Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging ', PLoS Genetics, vol. 14, no. 6, e1007379 . https://doi.org/10.1371/journal.pgen.1007379
Argonaute (AGO) proteins partner with microRNAs (miRNAs) to target specific genes for post-transcriptional regulation. During larval development in Caenorhabditis elegans, Argonaute-Like Gene 1 (ALG-1) is the primary mediator of the miRNA pathway, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c339d2036546fbb41164f18aa4f504
http://europepmc.org/articles/PMC6013023
http://europepmc.org/articles/PMC6013023
Autor:
Ying Hsin Chen, Laura B. Chipman, Sarah Azoubel Lima, Gene W. Yeo, Jeff Coller, Amy E. Pasquinelli, Brian A. Yee, Angela L. Nicholson
Publikováno v:
Nature structuralmolecular biology. 24(12)
Poly(A) tails are important elements in mRNA translation and stability, although recent genome-wide studies have concluded that poly(A) tail length is generally not associated with translational efficiency in nonembryonic cells. To investigate whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b658183eaf8f1a3f663c261d539bfed
https://pubmed.ncbi.nlm.nih.gov/29165425
https://pubmed.ncbi.nlm.nih.gov/29165425