Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Laura Alderfer"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Controlling the formation of new lymphatic vessels has been postulated as an innovative therapeutic strategy for various disease phenotypes, including neurodegenerative diseases, metabolic syndrome, cardiovascular disease, and lymphedema. Ye
Externí odkaz:
https://doaj.org/article/47d73249c9d24bf5a85a48f9d16f989b
Autor:
Loan Bui, Shanique Edwards, Eva Hall, Laura Alderfer, Kellen Round, Madeline Owen, Pietro Sainaghi, Siyuan Zhang, Prakash D. Nallathamby, Laura S. Haneline, Donny Hanjaya-Putra
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Drug-loaded liposomal nanoparticles conjugated to endothelial colony-forming cells can improve the vasculogenic potential of vascular progenitor cells exposed to gestational diabetes mellitus.
Externí odkaz:
https://doaj.org/article/e3e336f7c04149ae8bf89298209fb222
Autor:
Emilia A. Korhonen, Aino Murtomäki, Sawan Kumar Jha, Andrey Anisimov, Anne Pink, Yan Zhang, Simon Stritt, Inam Liaqat, Lukas Stanczuk, Laura Alderfer, Zhiliang Sun, Emmi Kapiainen, Abhishek Singh, Ibrahim Sultan, Anni Lantta, Veli-Matti Leppänen, Lauri Eklund, Yulong He, Hellmut G. Augustin, Kari Vaahtomeri, Pipsa Saharinen, Taija Mäkinen, Kari Alitalo
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 15 (2022)
Vascular endothelial growth factor C (VEGF-C) induces lymphangiogenesis via VEGF receptor 3 (VEGFR3), which is encoded by the most frequently mutated gene in human primary lymphedema. Angiopoietins (Angs) and their Tie receptors regulate lymphatic ve
Externí odkaz:
https://doaj.org/article/03f11650c1ac44279c6d8e5c233861e1
Publikováno v:
Journal of Biological Engineering, Vol 12, Iss 1, Pp 1-26 (2018)
Abstract The lymphatic system is a major circulatory system within the body, responsible for the transport of interstitial fluid, waste products, immune cells, and proteins. Compared to other physiological systems, the molecular mechanisms and underl
Externí odkaz:
https://doaj.org/article/9dd5e0a7371b4e22aeb4c86677442bf6
Autor:
Shanique K. E. Edwards, Laura Alderfer, Siyuan Zhang, Pietro Sainaghi, Loan Bui, Laura S. Haneline, Madeline Owen, Donny Hanjaya-Putra, Prakash Nallathamby, Kellen Round
Fetal exposure to gestational diabetes mellitus (GDM) predisposes children to future health complications including hypertension and cardiovascular disease. A key mechanism by which these complications occur is through stress-induced dysfunction of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07624476afba817dec3f8f8d2746f0d3
https://doi.org/10.21203/rs.3.rs-1047802/v1
https://doi.org/10.21203/rs.3.rs-1047802/v1
Autor:
Loan Bui, Shanique Edwards, Eva Hall, Laura Alderfer, Kellen Round, Madeline Owen, Pietro Sainaghi, Siyuan Zhang, Prakash D. Nallathamby, Laura S. Haneline, Donny Hanjaya-Putra
Publikováno v:
Communications biology. 5(1)
Fetal exposure to gestational diabetes mellitus (GDM) predisposes children to future health complications including type-2 diabetes mellitus, hypertension, and cardiovascular disease. A key mechanism by which these complications occur is through stre
Publikováno v:
Acta Biomater
The lymphatic system plays an integral part in regulating immune cell trafficking and the transport of macromolecules. However, its influence on disease progression and drug uptake is understood less than that of the vascular system. To bridge this k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37293f7be9fd8cd055ddbabaf3a9489
https://europepmc.org/articles/PMC9113193/
https://europepmc.org/articles/PMC9113193/
Autor:
Mark Walsh, Kimberly J. Curtis, Glen L. Niebur, Joseph Dynako, Alyssa G. Oberman, Hannah Martin, Laurie E. Littlepage, David I Zimmer, Laura Alderfer, Scott Thomas, Laoise M. McNamara, Ricardo Romero-Moreno, Stephen F Mitros, Christine Mai
Publikováno v:
Molecular Biology of the Cell
Metastasis is responsible for over 90% of cancer-related deaths, and bone is the most common site for breast cancer metastasis. Metastatic breast cancer cells home to trabecular bone, which contains hematopoietic and stromal lineage cells in the marr
Publikováno v:
FASEB J
Dysfunction of the lymphatic system is associated with a wide range of disease phenotypes. The restoration of dysfunctional lymphatic vessels has been hypothesized as an innovative method to rescue healthy phenotypes in diseased states including neur
Publikováno v:
Circulation. 142
Introduction: Fetal exposure to gestational diabetes mellitus (GDM) predisposes children to future health complications including hypertension and cardiovascular disease. A key mechanism by which these complications occur is through stress-induced dy