Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Laura A. Smith Callahan"'
Autor:
Nadine Matthias, Samuel D. Hunt, Jianbo Wu, Jonathan Lo, Laura A. Smith Callahan, Yong Li, Johnny Huard, Radbod Darabi
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 65-73 (2018)
Volumetric muscle defect, caused by trauma or combat injuries, is a major health concern leading to severe morbidity. It is characterized by partial or full thickness loss of muscle and its bio-scaffold, resulting in extensive fibrosis and scar forma
Externí odkaz:
https://doaj.org/article/e5a32a7bf48d48658af5a16239f06b82
Autor:
Laura A. Smith Callahan
Publikováno v:
Gels, Vol 2, Iss 2, p 18 (2016)
Combinatorial method/high throughput strategies, which have long been used in the pharmaceutical industry, have recently been applied to hydrogel optimization for tissue engineering applications. Although many combinatorial methods have been develope
Externí odkaz:
https://doaj.org/article/b85cd2cbd61944a18fecadb179bd818a
Publikováno v:
Journal of Functional Biomaterials, Vol 11, Iss 1, p 15 (2020)
Low neural tissue extracellular matrix (ECM) content has led to the understudy of its effects on neural cells and tissue. Hyaluronic acid (HA) and laminin are major neural ECM components, but direct comparisons of their cellular effects could not be
Externí odkaz:
https://doaj.org/article/2f32cbf376d04f84a50a3955748a6c8f
Publikováno v:
Biomacromolecules. 20:3009-3020
Cellular remodeling of the matrix has recently emerged as a key factor in promoting neural differentiation. Most strategies to manipulate matrix remodeling focus on proteolytically cleavable cross-linkers, leading to changes in tethered biochemical s
Autor:
Hyun Ju, Lim, Zara, Khan, Thomas S, Wilems, Xi, Lu, T Hiran, Perera, Yuki E, Kurosu, Krishna T, Ravivarapu, Matthew C, Mosley, Laura A, Smith Callahan
Publikováno v:
ACS biomaterials scienceengineering. 3(5)
Although preclinical models of spinal cord injury have shown that matrix inclusion in stem cell therapy leads to greater neurological improvements than that including cells alone, there has been insufficient matrix optimization for human cells.
Autor:
Ali Azhdarinia, Hyun Ju Lim, Qilin Cao, Thomas S. Wilems, Sukhen C. Ghosh, T. Hiran Perera, Laura A. Smith Callahan, Yi Yan Zheng
Publikováno v:
Journal of materials chemistry. B. 4(42)
Hyaluronic acid (HA) with one reactive moiety grafted to the backbone is a commonly used matrix in tissue engineering. The addition of a second orthogonal moiety to the backbone allows for greater control in bioactive signal tethering and gelation. I
Publikováno v:
Journal of Experimental Pharmacology
Polyethylene glycol (PEG) is a synthetic biocompatible polymer with many useful properties for developing therapeutics to treat spinal cord injury. Direct application of PEG as a fusogen to the injury site can repair cell membranes, mitigate oxidativ
Autor:
Laura A. Smith Callahan, Nadine Matthias, Yong Li, Jianbo Wu, Samuel D. Hunt, Radbod Darabi, Johnny Huard, Jonathan Lo
Publikováno v:
Stem cell research
Stem Cell Research, Vol 27, Iss, Pp 65-73 (2018)
Stem Cell Research, Vol 27, Iss, Pp 65-73 (2018)
Volumetric muscle defect, caused by trauma or combat injuries, is a major health concern leading to severe morbidity. It is characterized by partial or full thickness loss of muscle and its bio-scaffold, resulting in extensive fibrosis and scar forma
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:3059-3068
Many studies have utilized Irgacure 2959 photopolymerized poly(ethylene glycol) (PEG) hydrogels for tissue engineering application development. Due to the limited penetration of ultraviolet light through tissue, Irgacure 2959 polymerized hydrogels ar
Autor:
Hyun Ju Lim, Yuki E. Kurosu, Zara Khan, Laura A. Smith Callahan, Thomas S. Wilems, Matthew C. Mosley, T. Hiran Perera, Krishna T. Ravivarapu, Xi Lu
Publikováno v:
ACS Biomaterials Science & Engineering. 3:776-781
Although preclinical models of spinal cord injury have shown that matrix inclusion in stem cell therapy leads to greater neurological improvements than that including cells alone, there has been insufficient matrix optimization for human cells. N-Cad