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High-performance liquid chromatographic determination of carbamazepine and metabolites in human hair
Autor:
Ria V. Rademaker, Gerard J. van der Linden, Peter M. Edelbroek, Laura A. Saris, G. J. F. Brekelmans
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 691:409-415
To study the use of hair analysis in monitoring drug compliance and historical changes in pharmacokinetics we developed a method for the quantitative determination of the anti-epileptic drug carbamazepine (CBZ) and trans-10,11-dihydro-10,11-dihydroxy