Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Laura A. Philips"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Total holographic characterization (THC) is presented here as an efficient, automated, label-free method of accurately identifying cell viability. THC is a single-particle characterization technology that determines the size and index of ref
Externí odkaz:
https://doaj.org/article/ec508be2c81145dc8c7efd922d712889
Autor:
David G. Grier, Annemarie Winters, Fook Chiong Cheong, Mary Ann Odete, Laura A. Philips, Jesse J Elliott
Publikováno v:
Soft Matter
The in-line hologram of a micrometer-scale colloidal sphere can be analyzed with the Lorenz-Mie theory of light scattering to obtain precise measurements of the sphere's diameter and refractive index. The same technique also can be used to characteri
Publikováno v:
Scientific reports. 12(1)
Total holographic characterization (THC) is presented here as an efficient, automated, label-free method of accurately identifying cell viability. THC is a single-particle characterization technology that determines the size and index of refraction o
Autor:
Franziska Schleinzer, Dennis T. Yang, Dean C. Ripple, Nazar Filonov, Pascal Chalus, Tapan K. Das, Kurt D. Benkstein, Ashwinkumar A. Bhirde, Stefan Romeijn, Fook Chiong Cheong, Sambit R. Kar, Laura A. Philips, Christine Probst, Adam D. Grabarek, Nicole S. Gill, Maciej Jarzebski, Yoen Joo Kim, David L. Duewer, Miguel Saggu, Andrew D. Hollingsworth, Gurusamy Balakrishnan, Judith Hadley, Vikram Kestens, Yannic Ramaye, Anja Matter, Wesley W. Howard, Theodore W. Randolph, Ngoc Do, Jan Kuba Tatarkiewicz, David G. Grier, Heather Anne Wright, Patrick Garidel, Atanas Koulov, Wim Jiskoot, Jared R. Snell, Harshit Khasa
Publikováno v:
J Pharm Sci
Journal of Pharmaceutical Sciences
Journal of Pharmaceutical Sciences
The measurement of polydisperse protein aggregates and particles in biotherapeutics remains a challenge, especially for particles with diameters of ≈ 1 µm and below (sub-micrometer). This paper describes an interlaboratory comparison with the goal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebec099deb60130fdbf19d1d6774ab17
https://europepmc.org/articles/PMC9912188/
https://europepmc.org/articles/PMC9912188/
Autor:
David B. Ruffner, Laura A. Philips, Priya Kasimbeg, Jaroslaw M. Blusewicz, Fook Chiong Cheong
Publikováno v:
Journal of Pharmaceutical Sciences. 108:155-161
Characterizing protein aggregates in the presence of silicone oil is a long standing challenge for the pharmaceutical industry. Silicone oil is often used as a lubricant in devices that deliver and store therapeutic protein products and has been link
Autor:
Rushna Quddus, Kaitlynn Snyder, Lauren Altman, Laura A Philips, David G. Grier, Andrew D. Hollingsworth, Kent Kirshenbaum
This protocol describes the steps required to perform a holographic immunoassay for SARS-CoV-2 whole virus particles. The assay uses an xSight holographic particle characterization instrument (Spheryx, Inc.) to monitor the diameter of specifically fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5ae869c30191d5ad245e6d4a87276f1
https://doi.org/10.17504/protocols.io.bkpgkvjw
https://doi.org/10.17504/protocols.io.bkpgkvjw
Publikováno v:
Optics express. 26(10)
Micrometer sized particles can be accurately characterized using holographic video microscopy and Lorenz-Mie fitting. In this work, we explore some of the limitations in holographic microscopy and introduce methods for increasing the accuracy of this
Autor:
Laura A. Philips, Jeffrey R. McCutcheon, David G. Grier, Jaroslaw M. Blusewicz, David B. Ruffner, Priya Kasimbeg, Fook Chiong Cheong, Basma I. Waisi
Publikováno v:
Water research, 122, 431-439. Elsevier
Determining the size distribution and composition of particles suspended in water can be challenging in heterogeneous multicomponent samples. Light scattering techniques can measure the distribution of particle sizes, but provide no basis for disting
Publikováno v:
ECS Meeting Abstracts. :1034-1034
Holographic Microscopy is used to characterize sub-visible particles in CMP nanoparticles slurries. Results of these studies detect and identify a wide range of different large particle contaminants in nanoparticle slurries. Holographic characterizat
Autor:
David G. Grier, Fook Chiong Cheong, Ei Hnin Hlaing, Priya Kasimbeg, Jaroslaw M. Blusewicz, David B. Ruffner, Laura A. Philips
Publikováno v:
Applied Physics Letters. 111:153702
Holographic particle characterization uses in-line holographic microscopy and the Lorenz-Mie theory of light scattering to measure the diameter and the refractive index of individual colloidal particles in their native dispersions. This wealth of inf