Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Laura A. Nilson"'
Publikováno v:
Cell Reports, Vol 4, Iss 4, Pp 791-802 (2013)
Spatially restricted epidermal growth factor receptor (EGFR) activity plays a central role in patterning the follicular epithelium of the Drosophila ovary. In midoogenesis, localized EGFR activation is achieved by the graded dorsal anterior localizat
Externí odkaz:
https://doaj.org/article/021344daa04947df8d431835ae9ee680
Autor:
Tanja Starc, Michael P. O'Donnell, Pierre Drapeau, Joseph A. Dent, Laura D. Knogler, Daniel Feingold, Laura A. Nilson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products. The hormones act through G-protein-coupled receptors to activate second messenger systems that i
Autor:
Josée Houde, Mariana Fregoso Lomas, Scott De Vito, Laura A. Nilson, Jean-François Boisclair Lachance
Publikováno v:
Current Biology. 26:2572-2582
A relatively small number of signaling pathways drive a wide range of developmental decisions, but how this versatility in signaling outcome is generated is not clear. In the Drosophila follicular epithelium, localized epidermal growth factor recepto
Publikováno v:
Journal of Experimental Biology.
Pentameric ligand-gated ion channels (pLGICs) constitute a large protein superfamily in metazoa whose role as neurotransmitter receptors mediating rapid, ionotropic synaptic transmission has been extensively studied. Although the vast majority of pLG
Autor:
Laura A. Nilson, Caroline Laplante
Publikováno v:
The Journal of Cell Biology
Upon loss of a binding partner in apposed tissue, the homophilic cell adhesion protein Echinoid adopts a planar polarized localization, which promotes the planar polarized localization of the planar cell polarity protein Bazooka/Par-3 and targets act
Autor:
Caroline Laplante, Laura A. Nilson
Publikováno v:
Development. 133:3255-3264
Epithelial morphogenesis requires cell movements and cell shape changes coordinated by modulation of the actin cytoskeleton. We identify a role for Echinoid (Ed), an immunoglobulin domain-containing cell-adhesion molecule, in the generation of a cont
Autor:
Jean-François Boisclair Lachance, Laura A. Nilson, Matthew R. Atkey, Tahilia J. Rebello, Monica Walczak
Publikováno v:
Development. 133:2115-2123
The dorsoventral axis of the Drosophila egg is established by dorsally localized activation of the epidermal growth factor receptor (Egfr)in the ovarian follicular epithelium. Subsequent positive- and negative-feedback regulation generates two dorsol
Autor:
Wei-Ling Chang, Gail Barcelo, Shu-Ru Chen, Trudi Schüpbach, Li-Mei Pai, Laura A. Nilson, Pei-Yu Wang
Publikováno v:
Mechanisms of Development. 123:450-462
The Cbl family of proteins downregulate epidermal growth factor receptor (Egfr) signaling via receptor internalization and destruction. These proteins contain two functional domains, a RING finger domain with E3 ligase activity, and a proline rich do
Autor:
Trudi Schüpbach, Laura A Nilson
Publikováno v:
Cell. 93(2):253-262
Establishment of dorsoventral polarity within the Drosophila embryo requires extraembryonic positional information generated during oogenesis. The genes windbeutel, pipe, and nudel are required within the somatic follicle cells of the ovary for produ
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 239(9)
Morphogenesis of the Drosophila embryonic trachea involves a stereotyped pattern of epithelial tube branching and fusion. Here, we report unexpected phenotypes resulting from maternal and zygotic (M/Z) loss of the homophilic cell adhesion molecule Ec