Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laura A. Murray-Nerger"'
Autor:
Laura A. Murray-Nerger, Clarisel Lozano, Eric M. Burton, Yifei Liao, Nathan A. Ungerleider, Rui Guo, Benjamin E. Gewurz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Epstein-Barr virus (EBV) uses a biphasic lifecycle of latency and lytic reactivation to infect >95% of adults worldwide. Despite its central role in EBV persistence and oncogenesis, much remains unknown about how EBV latency is maintained. W
Externí odkaz:
https://doaj.org/article/5940750e74a64a30a216c017159bf86f
Autor:
Bidisha Mitra, Nina Rose Beri, Rui Guo, Eric M. Burton, Laura A. Murray-Nerger, Benjamin E. Gewurz
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThe Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1) mimics CD40 signaling and is expressed by multiple malignancies. Two LMP1 C-terminal cytoplasmic tail regions, termed transformation essential sites (TES) 1 and 2, are cri
Externí odkaz:
https://doaj.org/article/44232506b0514188a0d10b641da56aad
Autor:
Isabelle R. Taylor, Laura A. Murray-Nerger, Todd M. Greco, Dawei Liu, Ileana M. Cristea, Bonnie L. Bassler
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Pseudomonas aeruginosa is a human pathogen that relies on quorum sensing to establish infections. The PqsE quorum-sensing protein is required for P. aeruginosa virulence factor production and infection. PqsE has a reported enzymatic function
Externí odkaz:
https://doaj.org/article/afa784c005dc400da647a99424b9915b
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Here, Hashimoto et al. apply mass spectrometry-based thermal proximity coaggregation to characterize the temporal dynamics of virus-host protein-protein interactions during human cytomegalovirus (HCMV) infection, uncovering proviral functions includi
Externí odkaz:
https://doaj.org/article/0ca7fdb5104842789dbc540fcee827b1
Autor:
Chloe O. McCollum, Allison L. Didychuk, Dawei Liu, Laura A. Murray-Nerger, Ileana M. Cristea, Britt A. Glaunsinger
β- and γ-herpesviruses transcribe their late genes in a manner distinct from host transcription. This process is directed by a complex of viral transcriptional activator proteins that hijack cellular RNA polymerase II and an unknown set of addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68735314e0cbede4ccf0170445fbc39
https://doi.org/10.1101/2023.01.29.526158
https://doi.org/10.1101/2023.01.29.526158
Publikováno v:
Trends Biochem Sci
Nuclear lamins are ancient type V intermediate filaments with diverse functions that include maintaining nuclear shape, mechanosignaling, tethering and stabilizing chromatin, regulating gene expression, and contributing to cell cycle progression. Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d23125ee92b860b37fba4ef76743f63
https://doi.org/10.1016/j.tibs.2021.05.007
https://doi.org/10.1016/j.tibs.2021.05.007
Pseudomonas aeruginosa is a human pathogen that relies on quorum sensing to establish infections. The PqsE quorum-sensing protein is required for P. aeruginosa virulence factor production and infection. PqsE has a reported enzymatic function in the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::312a391b81000b69c98e3dd92ff08202
https://doi.org/10.1101/2022.05.31.494267
https://doi.org/10.1101/2022.05.31.494267
Autor:
Chloe O. McCollum, Allison L. Didychuk, Dawei Liu, Laura A. Murray-Nerger, Ileana M. Cristea, Britt A. Glaunsinger
Publikováno v:
PLoS pathogens, vol 19, iss 4
β- and γ-herpesviruses transcribe their late genes in a manner distinct from host transcription. This process is directed by a complex of viral transcriptional activator proteins that hijack cellular RNA polymerase II and an unknown set of addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d756848e97cbbc236e5dd7f6f3fc0a7
https://doi.org/10.1371/journal.ppat.1011163
https://doi.org/10.1371/journal.ppat.1011163
Autor:
Joshua L Justice, Laura A. Murray-Nerger, Pranav Rekapalli, Ileana M. Cristea, Josiah E. Hutton
Publikováno v:
Nucleic Acids Research
The integrity and regulation of the nuclear lamina is essential for nuclear organization and chromatin stability, with its dysregulation being linked to laminopathy diseases and cancer. Although numerous posttranslational modifications have been iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b63f1d82a6b6773e5d147542d34d8
https://doi.org/10.1093/nar/gkab019
https://doi.org/10.1093/nar/gkab019
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications
The co-evolution and co-existence of viral pathogens with their hosts for millions of years is reflected in dynamic virus-host protein-protein interactions (PPIs) that are intrinsic to the spread of infections. Here, we investigate the system-wide dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164174885ec83aa3aa814c02a883debb
https://doi.org/10.1038/s41467-020-14586-5
https://doi.org/10.1038/s41467-020-14586-5