Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura A. Maertens"'
Autor:
Valeria Guidolin, Erik S. Carlson, Andrea Carrà, Peter W. Villalta, Laura A. Maertens, Stephen S. Hecht, Silvia Balbo
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 366 (2021)
Alcohol consumption is a risk factor for the development of several cancers, including those of the head and neck and the esophagus. The underlying mechanisms of alcohol-induced carcinogenesis remain unclear; however, at these sites, alcohol-derived
Externí odkaz:
https://doaj.org/article/6c70f60122434510be7df14aeaea875a
Publikováno v:
Chemical Research in Toxicology. 36:769-781
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::346827eb3280e3fc8e81fe3e377b74a4
https://doi.org/10.1021/acs.chemrestox.3c00025
https://doi.org/10.1021/acs.chemrestox.3c00025
Autor:
Valeria Guidolin, Jing Yang, Viviana Paiano, Silvia Balbo, Stephen S. Hecht, Laura A. Maertens
Publikováno v:
Chem Res Toxicol
Cigarette smoking is an important source of human exposure to toxicants and carcinogens and contributes significantly to cancer morbidity and mortality worldwide. Acrolein, a widespread environmental pollutant, is present in relatively high amounts i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e2c575401ba76626bb32e292b17ea7
https://europepmc.org/articles/PMC8185904/
https://europepmc.org/articles/PMC8185904/
Autor:
Peter W. Villalta, Silvia Balbo, Valeria Guidolin, Erik S. Carlson, Andrea Carrà, Stephen S. Hecht, Laura A. Maertens
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 366, p 366 (2021)
Volume 11
Issue 3
Biomolecules, Vol 11, Iss 366, p 366 (2021)
Volume 11
Issue 3
Alcohol consumption is a risk factor for the development of several cancers, including those of the head and neck and the esophagus. The underlying mechanisms of alcohol-induced carcinogenesis remain unclear
however, at these sites, alcohol-deri
however, at these sites, alcohol-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f9c3ad37bbd458831fcaf9ba1e233a
https://doi.org/10.3390/biom11030366
https://doi.org/10.3390/biom11030366
Autor:
Romel P Dator, Linda B. von Weymarn, Cory J. Hooyman, Laura A. Maertens, Peter W. Villalta, Pramod Upadhyaya, Silvia Balbo, Sharon E. Murphy
Publikováno v:
Analytical chemistry. 90(20)
The tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), is a potent lung carcinogen and exerts its carcinogen effects upon metabolic activation. The identification and quantitation of NNK metabolites could identify pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ca75a58b4bc54228448464c28fa069
https://pubmed.ncbi.nlm.nih.gov/30086646
https://pubmed.ncbi.nlm.nih.gov/30086646
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 38(5)
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a lung-specific tobacco carcinogen. Metabolism is critical to its elimination given its lipophilic nature. Although NNK can be metabolized through detoxification pathways that safely eliminate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1648ed9f11810c252c8c5e7bbb4bb3af
https://pubmed.ncbi.nlm.nih.gov/20159989
https://pubmed.ncbi.nlm.nih.gov/20159989
Publikováno v:
Cancer Research. 70:1696-1696
(S)-NNAL and (R)-NNAL are metabolites of NNK, a tobacco-specific pulmonary carcinogen. The purpose of the current study was to compare the pulmonary metabolism of the NNAL enantiomers to determine if differences in metabolism are responsible for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a06658adb91a7ac2b6a8a8bbfe938845
https://doi.org/10.1158/1538-7445.am10-1696
https://doi.org/10.1158/1538-7445.am10-1696